ID G4T5B9_SERID Unreviewed; 1047 AA.
AC G4T5B9;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 45.
DE RecName: Full=ER membrane protein complex subunit 1 {ECO:0000256|ARBA:ARBA00020824};
GN ORFNames=PIIN_00183 {ECO:0000313|EMBL:CCA66499.1};
OS Serendipita indica (strain DSM 11827) (Root endophyte fungus)
OS (Piriformospora indica).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Sebacinales; Serendipitaceae; Serendipita.
OX NCBI_TaxID=1109443 {ECO:0000313|EMBL:CCA66499.1, ECO:0000313|Proteomes:UP000007148};
RN [1] {ECO:0000313|EMBL:CCA66499.1, ECO:0000313|Proteomes:UP000007148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11827 {ECO:0000313|EMBL:CCA66499.1,
RC ECO:0000313|Proteomes:UP000007148};
RX PubMed=22022265; DOI=10.1371/journal.ppat.1002290;
RA Zuccaro A., Lahrmann U., Guldener U., Langen G., Pfiffi S., Biedenkopf D.,
RA Wong P., Samans B., Grimm C., Basiewicz M., Murat C., Martin F.,
RA Kogel K.H.;
RT "Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of
RT the Mutualistic Root Symbiont Piriformospora indica.";
RL PLoS Pathog. 7:e1002290-e1002290(2011).
CC -!- SUBUNIT: Component of the ER membrane protein complex (EMC).
CC {ECO:0000256|ARBA:ARBA00011276}.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004115}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the EMC1 family.
CC {ECO:0000256|ARBA:ARBA00007904}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCA66499.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CAFZ01000002; CCA66499.1; -; Genomic_DNA.
DR AlphaFoldDB; G4T5B9; -.
DR STRING; 1109443.G4T5B9; -.
DR eggNOG; KOG2103; Eukaryota.
DR HOGENOM; CLU_005034_1_0_1; -.
DR InParanoid; G4T5B9; -.
DR OMA; SWAEVYH; -.
DR OrthoDB; 37872at2759; -.
DR Proteomes; UP000007148; Unassembled WGS sequence.
DR GO; GO:0072546; C:EMC complex; IEA:InterPro.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR026895; EMC1.
DR InterPro; IPR011678; EMC1_C.
DR InterPro; IPR002372; PQQ_repeat.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR21573:SF0; ER MEMBRANE PROTEIN COMPLEX SUBUNIT 1; 1.
DR PANTHER; PTHR21573; UNCHARACTERIZED; 1.
DR Pfam; PF07774; EMC1_C; 1.
DR Pfam; PF13360; PQQ_2; 1.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000007148};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..1047
FT /note="ER membrane protein complex subunit 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003468477"
FT DOMAIN 831..1045
FT /note="ER membrane protein complex subunit 1 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF07774"
SQ SEQUENCE 1047 AA; 113857 MW; A3661CDF18A8744C CRC64;
MKSVLLAGLL TALASSVNGI YESQVGQIDW HSQYIGVPWI HSPALAPRIH RVGSVRHGTP
AQAIYLAATK KNVLAALNPA EGNVVWRRQF DEDDALVGFK ANMDGLVSLS GNGGATARIY
EAINGNLIWE NHLHDPATGH LAGAAPGEPT GTAIEFDSID VFILSNGHTV RRLSGATGDT
LWGWTSPDMA SSTFLTSLVR TENALYVLGI SKGIRAFSIH ITSLDAATGT LLHSAEITAN
IDSADAFQVL KLGPAIGVCK TAGVVWLESG SLKQVLLTPG LEAKYLNKPS GNKYGPYVAL
KGLQVTERGY VSAILEEKDG QKDAVHIYKM DLGGLGLTKV GDFEPSPSTT PYTTYAGGID
REGRAYVSKL AHSSTLRSAS YEVFAPDAVN GRGMTTGFTF EYDSSAHGEI TFAALDVANP
SEYIYVSRII LSTSTGAIQQ WQQETNHWSR EESLTEIEAV AALDLPEATV DSRLMYTAME
ETPIQRITRQ VRDMKDLPFY LFRFIQRFMT GKYSTVPTSG SNTAGSLWRD LYGFKKVLVI
ATARGKVFGI ETNKGTIVWS EKLGANSPDL SMKIKPVRMT VLKTVSEGFH PEVGIVVEVD
RANNQGGRTL TTGLVRVDAT TGSSHSIVLF HGPTLEVKEI DLPNPSAGLG KKMIAVVDYD
YKVHLYPYHR EALEAFNNIT DRSTFMLVTG PPTSQFVQGY GISHRILPVE ELDNGTSTTL
EPVWDTYPTW RSNVGPGEKI VSTVYRTPGS AASHGRVLAD RTTLYKYLNP HLAAVVTETR
ARHGANPAGT PRARCTIYLI DASKGTVLYS TNVPSSKRTS LACDVKMTLV ENWLVYHYYE
DSSEYGEAGT KGWRMVSVEL YEGGPNVRLK SGELGPESPK RGSIETLEQV YVFPSDIRTI
ATTSTKFGIS SKDIIVINGK GQVQTFSRRF LDPRRPKSKP TAAEAEEGLI QFDVLLPDDS
RRVVSHNRGV YADKLLTTST SLESTSLVLA YGTDLFLTRV SPSGTFDVLS AGFNKIQLVL
TVSGLGAAIL ITRPLVRSKV LNARWYA
//
