ID   G4T6U9_SERID            Unreviewed;       371 AA.
AC   G4T6U9;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 45.
DE   SubName: Full=Probable IDH1-isocitrate dehydrogenase [NAD] subunit 1, mitochondrial {ECO:0000313|EMBL:CCA67040.1};
GN   ORFNames=PIIN_00877 {ECO:0000313|EMBL:CCA67040.1};
OS   Serendipita indica (strain DSM 11827) (Root endophyte fungus)
OS   (Piriformospora indica).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Sebacinales; Serendipitaceae; Serendipita.
OX   NCBI_TaxID=1109443 {ECO:0000313|EMBL:CCA67040.1, ECO:0000313|Proteomes:UP000007148};
RN   [1] {ECO:0000313|EMBL:CCA67040.1, ECO:0000313|Proteomes:UP000007148}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11827 {ECO:0000313|EMBL:CCA67040.1,
RC   ECO:0000313|Proteomes:UP000007148};
RX   PubMed=22022265; DOI=10.1371/journal.ppat.1002290;
RA   Zuccaro A., Lahrmann U., Guldener U., Langen G., Pfiffi S., Biedenkopf D.,
RA   Wong P., Samans B., Grimm C., Basiewicz M., Murat C., Martin F.,
RA   Kogel K.H.;
RT   "Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of
RT   the Mutualistic Root Symbiont Piriformospora indica.";
RL   PLoS Pathog. 7:e1002290-e1002290(2011).
CC   -!- SIMILARITY: Belongs to the isocitrate and isopropylmalate
CC       dehydrogenases family. {ECO:0000256|ARBA:ARBA00007769}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCA67040.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CAFZ01000008; CCA67040.1; -; Genomic_DNA.
DR   AlphaFoldDB; G4T6U9; -.
DR   STRING; 1109443.G4T6U9; -.
DR   eggNOG; KOG0784; Eukaryota.
DR   HOGENOM; CLU_031953_0_1_1; -.
DR   InParanoid; G4T6U9; -.
DR   OMA; TCAHKAN; -.
DR   OrthoDB; 143577at2759; -.
DR   Proteomes; UP000007148; Unassembled WGS sequence.
DR   GO; GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
DR   Gene3D; 3.40.718.10; Isopropylmalate Dehydrogenase; 1.
DR   InterPro; IPR004434; Isocitrate_DH_NAD.
DR   InterPro; IPR024084; IsoPropMal-DH-like_dom.
DR   NCBIfam; TIGR00175; mito_nad_idh; 1.
DR   PANTHER; PTHR11835; DECARBOXYLATING DEHYDROGENASES-ISOCITRATE, ISOPROPYLMALATE, TARTRATE; 1.
DR   PANTHER; PTHR11835:SF42; ISOCITRATE DEHYDROGENASE [NAD] SUBUNIT GAMMA, MITOCHONDRIAL; 1.
DR   Pfam; PF00180; Iso_dh; 1.
DR   SMART; SM01329; Iso_dh; 1.
DR   SUPFAM; SSF53659; Isocitrate/Isopropylmalate dehydrogenase-like; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007148};
KW   Transit peptide {ECO:0000256|ARBA:ARBA00022946}.
FT   DOMAIN          43..367
FT                   /note="Isopropylmalate dehydrogenase-like"
FT                   /evidence="ECO:0000259|SMART:SM01329"
SQ   SEQUENCE   371 AA;  40311 MW;  FAD5913C2AAF31AA CRC64;
     MLRNTLAAAA RRPLVLQRSA TTLAAGFPKV SKRLPTKYGG VYTVTLIPGD GIGKEVTDSV
     KEIFEHVNAP IEWEQYDVSG MSNEGEALFN QAMESLKRNR VGLKGILFTP IEGHLSWNVA
     MRQQLDIYAS VVLCKSLPGV PTRHQNVDFA IIRENTEGEY SGLEHQSFPG VVESLKVSTR
     HKSERIIRFA FDFALKNNRK KITCVHKANI MKLGDGLFLN TFRRVAEEYK SSGIVANDMI
     VDNTSMQLVA KPGQFDVMVM PNLYGAIVSN IGAALVGGPG VVPGCNVGRE YALFEPGCRH
     VAEDIKGTNK ANPAAMILSA TMMLRHLGLD STANSIASAT FDVLNAKKVR TADMGGSATT
     SDFTAAVIQH L
//