ID G4TNU7_SERID Unreviewed; 1766 AA.
AC G4TNU7;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00012494};
DE EC=2.7.7.48 {ECO:0000256|ARBA:ARBA00012494};
GN ORFNames=PIIN_06945 {ECO:0000313|EMBL:CCA72990.1};
OS Serendipita indica (strain DSM 11827) (Root endophyte fungus)
OS (Piriformospora indica).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Sebacinales; Serendipitaceae; Serendipita.
OX NCBI_TaxID=1109443 {ECO:0000313|EMBL:CCA72990.1, ECO:0000313|Proteomes:UP000007148};
RN [1] {ECO:0000313|EMBL:CCA72990.1, ECO:0000313|Proteomes:UP000007148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11827 {ECO:0000313|EMBL:CCA72990.1,
RC ECO:0000313|Proteomes:UP000007148};
RX PubMed=22022265; DOI=10.1371/journal.ppat.1002290;
RA Zuccaro A., Lahrmann U., Guldener U., Langen G., Pfiffi S., Biedenkopf D.,
RA Wong P., Samans B., Grimm C., Basiewicz M., Murat C., Martin F.,
RA Kogel K.H.;
RT "Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of
RT the Mutualistic Root Symbiont Piriformospora indica.";
RL PLoS Pathog. 7:e1002290-e1002290(2011).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate +
CC RNA(n+1); Xref=Rhea:RHEA:21248, Rhea:RHEA-COMP:14527, Rhea:RHEA-
CC COMP:17342, ChEBI:CHEBI:33019, ChEBI:CHEBI:61557, ChEBI:CHEBI:140395;
CC EC=2.7.7.48; Evidence={ECO:0000256|ARBA:ARBA00024517};
CC -!- SIMILARITY: Belongs to the RdRP family.
CC {ECO:0000256|ARBA:ARBA00005762}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCA72990.1}.
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DR EMBL; CAFZ01000195; CCA72990.1; -; Genomic_DNA.
DR STRING; 1109443.G4TNU7; -.
DR eggNOG; KOG0988; Eukaryota.
DR HOGENOM; CLU_238943_0_0_1; -.
DR InParanoid; G4TNU7; -.
DR OrthoDB; 2735303at2759; -.
DR Proteomes; UP000007148; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003968; F:RNA-dependent RNA polymerase activity; IEA:UniProtKB-KW.
DR GO; GO:0031047; P:regulatory ncRNA-mediated gene silencing; IEA:UniProt.
DR InterPro; IPR007855; RNA-dep_RNA_pol_euk-typ.
DR PANTHER; PTHR23079; RNA-DEPENDENT RNA POLYMERASE; 1.
DR PANTHER; PTHR23079:SF14; RNA-DEPENDENT RNA POLYMERASE; 1.
DR Pfam; PF05183; RdRP; 1.
PE 3: Inferred from homology;
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000313|EMBL:CCA72990.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007148};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884};
KW RNA-directed RNA polymerase {ECO:0000256|ARBA:ARBA00022484,
KW ECO:0000313|EMBL:CCA72990.1}; Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT REGION 100..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 214..438
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 450..539
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 560..619
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 700..720
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..114
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 214..244
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 245..260
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 279..299
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 347..362
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 410..438
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 457..473
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 484..501
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..530
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 576..619
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1766 AA; 195499 MW; D7A153693D64C097 CRC64;
MSSSSGSFRW RFRKGSMVFT GTREEFENAL RLQFSSTSRD RPSHPQANQN LVQSIKARTW
DTLSQNEKSL GIRDAVDAEL VATSTRPSSL TPCIPSRLSQ EVDRRMDRRE SSSEDVQLAT
SPSREDARNR YYVDVGVQCS EVADLENADA VVHRSPEISD STELHGISEA SDQAQSIRQA
LDVGVAWISG QVNQMDINTE VEIKYPALPT RVSLPQSCSC SQGSTPPIPG AFPESTQPHL
NVSHESLRRS LRDRGDSSAH RPQRLATSEV LHSVQAAPVD HPTNASSSAS SSTNPSAGRV
TVGKIGAPVE NSHHSPLSRP RVLVGSGASN SGSRSHTPIV DFRAARQSQR RASTRVSPTV
SNPPTRPHSP LSISPGKAHP DNDLAIPYGD PLDGGSTVES YQRTRPMNSD KGKGVAHPRG
GTDARESDYE SHVSESEFED DFNMVPRLLS PRSRYPPVQH RTVSPSSLPG NLKSPIPAVS
RLSPSMYSHR STTSTAKKGG SAEQTPRPRL KPFSTTVIAP SSQNESVSEH DTSFQSEDEE
LFDSVSDIDL SQLDISPALP QSSDEAEHRH PVPSGTKAAQ RSSVTIIQPT APTPLSRNPG
ASSSLTMVAR QQRQPAPSVP LVSLKNLPRD VRLRNPHVLA HAPRHQDVWN DLPVGTAFQV
ALMAQNLGVD LEAITKKSVI PLTEKGNEMI KAVESVLREA MTSQGGGQPS YSRRNDDETD
VEDYVTDVET DSEMFVRPGN QTPQATNTSL DQVAAELDWE AEQIILGTGD MLGWREERGT
RYGGKVQFAA TLKFNDEDPS GKSQSQKSSS PLLDLESQGR IVLEPLCLRG SSIFTRTLGS
HRFLRMRISS AIQRHVGVWS NSSAEERSEN KRRLREYVQR PLFILGRVYV PMLEKDGVIL
YFLEGKESVG EFFEQQFKLP RGRSYGVVEC QTLQGLINWW VPLKYNEKQD MSKLATRLEL
GFSDTLPGVL LEPAHIHVVN DIENDDGTVF TDGAGLMTPS LARTLARKYP TKDQRDRDAL
DTPVAYQIRV QTAKGVVLID PDMLVDRNFD GPHRLLLSKS MCKAARGNKP LRPGPVNGMH
ILDAADCIVC IVKPAPVSAS TGVRLSSQFI TVLSSCGVPD DVFLQIQHDA LEKELEAWTD
IETEEVNKGH RINENTRLRM ASLISHTQSL VLTIKKRELG GEAKGLGYGR RTKRETEAGY
ESEEETKPSL VHANSFDSFS SMATGSGNLE LRSVPAYTHN EISGFPASKG QALHDALLAG
IEVHKSNYWL KLWSEMASEA MMRVVAKFHL PVERSACGFL QPDFTGSLKE GEVFFSPKSA
MVDSETGLAV QFIEGDVIVG RHPALLPTDM RKVKAVFVPK LQDFKGILFC SIHGELPLAS
ILAGGDYDGD EGTIIWEQRI VHPFKNAPLH LREPPPGFDD KFGKVTEKVS DVNKEASSYD
ASEYAAILAP RLIASVGEGD TFKIYNSFWN MAVHRYGLWY PENDKELSPA VEMAHKFNVL
MDSKKSGLRI RDEELTHDHR EWSKFSEPYW RQRQMELDKK ETFIKEHNPK SLESKGGDIP
ILDRLAYAGE KQVDEEIKRL KDRVDASREE NDLFFLGNGT DEDLAAPWNA AVNFAKGNRV
YEAQLDAIKV FVKDCFDAMK RISVETARRR CTARQRTNEI RAICTRFAEF QPPLDEGQPS
MFGVLDADAV RGRVMASCMY VHDMLHGGSR RGGSTNGLGW QIAFRELCAI KSKTVSKGDT
VSLPRTVHEK RETHKYWGRT RTILSM
//
