ID G4TPU7_SERID Unreviewed; 769 AA.
AC G4TPU7;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Probable RAS GTPase-activating protein sar1 {ECO:0000313|EMBL:CCA73340.1};
GN ORFNames=PIIN_07295 {ECO:0000313|EMBL:CCA73340.1};
OS Serendipita indica (strain DSM 11827) (Root endophyte fungus)
OS (Piriformospora indica).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Sebacinales; Serendipitaceae; Serendipita.
OX NCBI_TaxID=1109443 {ECO:0000313|EMBL:CCA73340.1, ECO:0000313|Proteomes:UP000007148};
RN [1] {ECO:0000313|EMBL:CCA73340.1, ECO:0000313|Proteomes:UP000007148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11827 {ECO:0000313|EMBL:CCA73340.1,
RC ECO:0000313|Proteomes:UP000007148};
RX PubMed=22022265; DOI=10.1371/journal.ppat.1002290;
RA Zuccaro A., Lahrmann U., Guldener U., Langen G., Pfiffi S., Biedenkopf D.,
RA Wong P., Samans B., Grimm C., Basiewicz M., Murat C., Martin F.,
RA Kogel K.H.;
RT "Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of
RT the Mutualistic Root Symbiont Piriformospora indica.";
RL PLoS Pathog. 7:e1002290-e1002290(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCA73340.1}.
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DR EMBL; CAFZ01000218; CCA73340.1; -; Genomic_DNA.
DR AlphaFoldDB; G4TPU7; -.
DR STRING; 1109443.G4TPU7; -.
DR eggNOG; KOG2128; Eukaryota.
DR HOGENOM; CLU_009455_0_0_1; -.
DR InParanoid; G4TPU7; -.
DR OMA; EAYMITL; -.
DR OrthoDB; 24454at2759; -.
DR Proteomes; UP000007148; Unassembled WGS sequence.
DR GO; GO:0005096; F:GTPase activator activity; IEA:UniProt.
DR CDD; cd05132; RasGAP_GAPA; 1.
DR InterPro; IPR000593; RasGAP_C.
DR InterPro; IPR023152; RasGAP_CS.
DR InterPro; IPR001936; RasGAP_dom.
DR InterPro; IPR008936; Rho_GTPase_activation_prot.
DR PANTHER; PTHR14149:SF17; GTPASE-ACTIVATING PROTEIN; 1.
DR PANTHER; PTHR14149; RAS GTPASE-ACTIVATING PROTEIN WITH IQ MOTIF; 1.
DR Pfam; PF00616; RasGAP; 1.
DR Pfam; PF03836; RasGAP_C; 1.
DR SMART; SM00323; RasGAP; 1.
DR SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR SUPFAM; SSF143885; RGC domain-like; 1.
DR PROSITE; PS00509; RAS_GTPASE_ACTIV_1; 1.
DR PROSITE; PS50018; RAS_GTPASE_ACTIV_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000007148}.
FT DOMAIN 163..379
FT /note="Ras-GAP"
FT /evidence="ECO:0000259|PROSITE:PS50018"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 37..64
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 769 AA; 87771 MW; 79FE2750BE99A293 CRC64;
MSSFIDSGSP TDSRRLTNRN TNRYSVNQLY SMAAENDTDI EDDLSRAQKR LRDLKARISA
QSKKNFVLER DVRYLDSRIA LLIQNRMALD EQNEVQQHLE EIEPNEGVFP PERKLTQYSN
LFFLLQSEPR HIASLCRLVS LAEIDTLLQT VMFTLYGNQY ESREEHLLLT MFQSVLSAQF
ETATEFGSLL RANTPVSRMM TTYTRRGPGQ SYLKSVLSDR INSLIEHRDL NLEINPLKVY
EQMVTQIEEE TGSLPPNLPR GVAPETAAAN LDVQAIIAPR LTMLMEIANS FLLTIIESME
TVPYGIRWIC KQIRSLTRRK YPDATDYAIC SLIGGFFFLR FINPAIVTPQ AYMLVDGVPA
KHPRRTLTLI AKMLQNLANK PSYAKEAYMA SLNPFVENNK ARINLFLNNL CEVGDFYDTL
EMDQYMALSK KDLMIHITLN ELYNTHSLLN QHIGVLAPND KSHLRILLEE LGPAPGQVPR
KENRTVDLSL FSRWETPIQD ITTALMAENN ITQNEILYME TKSIFVQLIR SIPHAADKRP
INLSAIAEKA ATSKDATLVR RGIKVKEMLR ELEELKVVDR KDDYKLMQEE VAAELVHLGN
MREKVLQESR SLEAVYKTIC DHNNYLRSQL EQYKAYLQNV RFAADKGAAG GVGVLAYGGK
ERKPAKTAPQ GPFRFTHAQL EKEGIIVESN VPDNRRPNIY FNISSPTPGT FIIALHYKGR
EKAILEMDLK IDDLLEKQKD NKHLLDLEYV QLNVPKVLGL LNKIFSKKK
//
