ID   G4TTT8_SERID            Unreviewed;       414 AA.
AC   G4TTT8;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 44.
DE   RecName: Full=cysteine synthase {ECO:0000256|ARBA:ARBA00012681};
DE            EC=2.5.1.47 {ECO:0000256|ARBA:ARBA00012681};
GN   ORFNames=PIIN_08690 {ECO:0000313|EMBL:CCA74731.1};
OS   Serendipita indica (strain DSM 11827) (Root endophyte fungus)
OS   (Piriformospora indica).
OC   Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC   Sebacinales; Serendipitaceae; Serendipita.
OX   NCBI_TaxID=1109443 {ECO:0000313|EMBL:CCA74731.1, ECO:0000313|Proteomes:UP000007148};
RN   [1] {ECO:0000313|EMBL:CCA74731.1, ECO:0000313|Proteomes:UP000007148}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11827 {ECO:0000313|EMBL:CCA74731.1,
RC   ECO:0000313|Proteomes:UP000007148};
RX   PubMed=22022265; DOI=10.1371/journal.ppat.1002290;
RA   Zuccaro A., Lahrmann U., Guldener U., Langen G., Pfiffi S., Biedenkopf D.,
RA   Wong P., Samans B., Grimm C., Basiewicz M., Murat C., Martin F.,
RA   Kogel K.H.;
RT   "Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of
RT   the Mutualistic Root Symbiont Piriformospora indica.";
RL   PLoS Pathog. 7:e1002290-e1002290(2011).
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000256|ARBA:ARBA00001933};
CC   -!- SIMILARITY: Belongs to the cysteine synthase/cystathionine beta-
CC       synthase family. {ECO:0000256|ARBA:ARBA00007103}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:CCA74731.1}.
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DR   EMBL; CAFZ01000348; CCA74731.1; -; Genomic_DNA.
DR   AlphaFoldDB; G4TTT8; -.
DR   STRING; 1109443.G4TTT8; -.
DR   eggNOG; KOG1481; Eukaryota.
DR   HOGENOM; CLU_021018_1_0_1; -.
DR   InParanoid; G4TTT8; -.
DR   OMA; WMADYGF; -.
DR   OrthoDB; 852805at2759; -.
DR   Proteomes; UP000007148; Unassembled WGS sequence.
DR   GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR   CDD; cd01561; CBS_like; 1.
DR   Gene3D; 3.40.50.1100; -; 2.
DR   InterPro; IPR001216; P-phosphate_BS.
DR   InterPro; IPR001926; TrpB-like_PALP.
DR   InterPro; IPR036052; TrpB-like_PALP_sf.
DR   PANTHER; PTHR10314; CYSTATHIONINE BETA-SYNTHASE; 1.
DR   PANTHER; PTHR10314:SF35; MITOCHONDRIAL CYSTEINE SYNTHASE-RELATED; 1.
DR   Pfam; PF00291; PALP; 1.
DR   SUPFAM; SSF53686; Tryptophan synthase beta subunit-like PLP-dependent enzymes; 1.
DR   PROSITE; PS00901; CYS_SYNTHASE; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000007148}.
FT   DOMAIN          49..373
FT                   /note="Tryptophan synthase beta chain-like PALP"
FT                   /evidence="ECO:0000259|Pfam:PF00291"
SQ   SEQUENCE   414 AA;  44488 MW;  B0B371520A25E5A4 CRC64;
     MAAKRQNIDL LIGIAIGLAF SASTISLVNR FTSWLGRRKE EDIVDGVPGL IGNTPLLRIK
     SLSDALGVDI LGKAEFLNPG GSVKDRVAMK IIDDAEASGY LKPGIGSRIF EGTVGSTGIS
     IATLAAARGY NTTIIMPDDV AAEKALALRA LGADVEKVRP ASIVDKKQFV NLAKSKAAAY
     GTNARSLPGL DGVVSSDQDL DAKDQPRGFF ADQFENRSNF EAHYQGTGPE IWRQSGCKVD
     AFVSGAGTGG TIAGAGQYLR EKNPKIIVVL SDPEGSGLYN KVKHGVMFDA KESEGRKRRH
     QVDTVVEGIG INRLTKNFEY ALPIIDDAIR VSDVEAVSMS RFIVKNDACN LVAAVKVAKR
     LPRSGRVVTI LCDSGSRHYS KFWNDEYLEA AGIRVDISLT EDLLKQNTIQ STSK
//