ID G4U3C2_SERID Unreviewed; 793 AA.
AC G4U3C2;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 53.
DE SubName: Full=Related to AAA protease IAP-1 (Mitochondrial intermembrane space) {ECO:0000313|EMBL:CCA78061.1};
GN ORFNames=PIIN_01736 {ECO:0000313|EMBL:CCA78061.1};
OS Serendipita indica (strain DSM 11827) (Root endophyte fungus)
OS (Piriformospora indica).
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Sebacinales; Serendipitaceae; Serendipita.
OX NCBI_TaxID=1109443 {ECO:0000313|EMBL:CCA78061.1, ECO:0000313|Proteomes:UP000007148};
RN [1] {ECO:0000313|EMBL:CCA78061.1, ECO:0000313|Proteomes:UP000007148}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 11827 {ECO:0000313|EMBL:CCA78061.1,
RC ECO:0000313|Proteomes:UP000007148};
RX PubMed=22022265; DOI=10.1371/journal.ppat.1002290;
RA Zuccaro A., Lahrmann U., Guldener U., Langen G., Pfiffi S., Biedenkopf D.,
RA Wong P., Samans B., Grimm C., Basiewicz M., Murat C., Martin F.,
RA Kogel K.H.;
RT "Endophytic Life Strategies Decoded by Genome and Transcriptome Analyses of
RT the Mutualistic Root Symbiont Piriformospora indica.";
RL PLoS Pathog. 7:e1002290-e1002290(2011).
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: In the C-terminal section; belongs to the peptidase M41
CC family. {ECO:0000256|ARBA:ARBA00010044}.
CC -!- SIMILARITY: In the N-terminal section; belongs to the AAA ATPase
CC family. {ECO:0000256|ARBA:ARBA00010550}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:CCA78061.1}.
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DR EMBL; CAFZ01001883; CCA78061.1; -; Genomic_DNA.
DR AlphaFoldDB; G4U3C2; -.
DR STRING; 1109443.G4U3C2; -.
DR eggNOG; KOG0734; Eukaryota.
DR HOGENOM; CLU_000688_9_2_1; -.
DR InParanoid; G4U3C2; -.
DR OMA; MSHFEWA; -.
DR OrthoDB; 9585at2759; -.
DR Proteomes; UP000007148; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.
DR GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd19501; RecA-like_FtsH; 1.
DR Gene3D; 1.10.8.60; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.20.58.760; Peptidase M41; 1.
DR HAMAP; MF_01458; FtsH; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR041569; AAA_lid_3.
DR InterPro; IPR003959; ATPase_AAA_core.
DR InterPro; IPR003960; ATPase_AAA_CS.
DR InterPro; IPR005936; FtsH.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000642; Peptidase_M41.
DR InterPro; IPR037219; Peptidase_M41-like.
DR PANTHER; PTHR23076:SF37; ATP-DEPENDENT ZINC METALLOPROTEASE YME1L1; 1.
DR PANTHER; PTHR23076; METALLOPROTEASE M41 FTSH; 1.
DR Pfam; PF00004; AAA; 1.
DR Pfam; PF17862; AAA_lid_3; 1.
DR Pfam; PF01434; Peptidase_M41; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF140990; FtsH protease domain-like; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00674; AAA; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metalloprotease {ECO:0000256|ARBA:ARBA00023049};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000313|EMBL:CCA78061.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000007148}.
FT DOMAIN 384..520
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
SQ SEQUENCE 793 AA; 86424 MW; 422748B0634E630F CRC64;
MQALGQLSGL SQTLQLLQPA WLTIQPVRIP QPLKLSINPV DPLVPTRNYA AEVLQAAPPS
LNNSRILKLS YIPPQTAQTV LLRGARRPAT TAHPSSHGRR HLWTSIQKKI RSLRPERVTS
PLVYSQIVRL ETEANAFPNN VAKQVTLWRA IMELDTPSAY DKIISRWERL LEFAPNSQII
KSDAAFRLYL MALLKKGDAK SIWLAAARRD QVLQTVGAAP TEPAAVEEEP ASASKVTQSP
SHDIAEAVLS DPAITNTPTW AIGDSGLGKS SGGTGVLAGI QAGSKQQPLH VMVAQPKGSV
AWQIGKTLLI VGLYGFLTLT ILGLVLENSG VLKTNTQVTE FEQSGGEPVK FSDVHGVEEA
KEELQDIVEF LKNPSSFSTL GGKLPKGVLL EGPPGTGKTL LARAVAGEAG VPFFFASGSD
FDEIFVGVGA KRIRELFAAA RKKQPAIIFI DELDAVGGKR SPKDQQFMKQ TLNQLLVELD
GFKQSEGIIV IGATNFPQSL DKALVRPGRF DRKVVVPLPD VKGRVQILKH HMKNVVNDPS
VDVELLARVT VGFSGADLQN MVNQAAVQAS KEHADAVKIR HYEWARDKIG MGPERRSAVM
EEKVKLAVAY HEGGHALSAL FTKGAMPLYK VTCMPRGQAL GVTHQAPVND RTSVTFTEYL
ADMDVCTGGR AAEEFIYGKE NITSGASSDL VRATDIARSM VRHWGFSDKV GRVVYREEDA
AMISPQKKDE IESEVKRLVE ESCTRSMNLI KSKETELHRL AKALVEHETL DAEEVKKVIA
GEKIRVAEKL ADA
//
