ID   G4U749_NEUT9            Unreviewed;       763 AA.
AC   G4U749;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 47.
DE   RecName: Full=Rad21/Rec8-like protein N-terminal domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=NEUTE2DRAFT_52087 {ECO:0000313|EMBL:EGZ77451.1};
OS   Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ77451.1, ECO:0000313|Proteomes:UP000008513};
RN   [1] {ECO:0000313|EMBL:EGZ77451.1, ECO:0000313|Proteomes:UP000008513}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX   PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA   Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA   Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT   "Massive changes in genome architecture accompany the transition to self-
RT   fertility in the filamentous fungus Neurospora tetrasperma.";
RL   Genetics 189:55-69(2011).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the rad21 family.
CC       {ECO:0000256|ARBA:ARBA00009870}.
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DR   EMBL; GL890999; EGZ77451.1; -; Genomic_DNA.
DR   AlphaFoldDB; G4U749; -.
DR   STRING; 510952.G4U749; -.
DR   eggNOG; KOG1213; Eukaryota.
DR   HOGENOM; CLU_025342_0_0_1; -.
DR   Proteomes; UP000008513; Unassembled WGS sequence.
DR   GO; GO:0008278; C:cohesin complex; IEA:InterPro.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007062; P:sister chromatid cohesion; IEA:InterPro.
DR   CDD; cd21789; Rad21_Rec8_M_SpRec8p-like; 1.
DR   Gene3D; 1.10.10.580; Structural maintenance of chromosome 1. Chain E; 1.
DR   InterPro; IPR039781; Rad21/Rec8-like.
DR   InterPro; IPR006909; Rad21/Rec8_C_eu.
DR   InterPro; IPR006910; Rad21_Rec8_N.
DR   InterPro; IPR023093; ScpA-like_C.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR12585:SF70; RAD21_REC8 N TERMINAL DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_6G02900); 1.
DR   PANTHER; PTHR12585; SCC1 / RAD21 FAMILY MEMBER; 1.
DR   Pfam; PF04824; Rad21_Rec8; 1.
DR   Pfam; PF04825; Rad21_Rec8_N; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008513}.
FT   DOMAIN          1..115
FT                   /note="Rad21/Rec8-like protein N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04825"
FT   DOMAIN          697..732
FT                   /note="Rad21/Rec8-like protein C-terminal eukaryotic"
FT                   /evidence="ECO:0000259|Pfam:PF04824"
FT   REGION          248..295
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          458..567
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          582..637
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          666..685
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        458..476
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        528..556
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   763 AA;  83132 MW;  993CC137E8315AA5 CRC64;
     MFYSHEILTN QQYGVATVWL VSTFGLRSSN RKISRKAIQE VNVRKACETI LQPGAPIALR
     LQGSLLYGVS RVFSQQCSYV LTDAEKIHMH MRCFYNVLGG TENALDPQAG KAKRNQLILP
     DDPNFEVNMG LPAFHLDEDG NLASLFQSQA SCKTSSQFSP LDRFNLTPDG SGSFLLGLDL
     PQSSPVDPLY SQHSSYFLGP LSQHKPDDDM MEFGEPEANA EIFGDWGIEI DADGNVMATV
     DEPELPVLPR PEEERTRATA FGQGHNESEL SFDDQGDLLM SGGTAPPPDA DEVPGLVPDQ
     VEQAQEDQFM EEVEEAQVIA EEPVVEAVAT PVQRRQRRRT VLVPDHDTKI SRHELKSWST
     DYLANAERAN NAAVRAAAMN PTTAKKHAYE LIFGRGVGRV GALESGLNSG NHRSHPLAAL
     FSGANFASEA LGIDIDEEVE AEGRRSRRRT ALEALELEEE DAERRVRRRL SDENGEEHQA
     QAQQNAEPQT EAGRGGLPTG GAEEDAEIGR RDGSALPDIP SDAPWNRPSS LVPGSSVKGD
     NHHLGSSRQV SASPLHSRGS HLAHLPPIDR FSDAGSYAPF LHSGGAPGFS SDPIMPPGED
     EPQLPHLPGG PRGGRDLLRR TPSGEAETTA TQAAAETSQV MRDALDRDGH NFLAYVNMVA
     KARGETRSLG GGEAPPSSSH AHGDGNDRLL RQWVAFDELL DEPRDRTRQV ATQAFYNVLV
     LATKDAIKVE QDMEGFQSFG EIRVGVEVSE AEMLALMEED GDE
//