ID G4U8R1_NEUT9 Unreviewed; 603 AA.
AC G4U8R1;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=Carboxylic ester hydrolase {ECO:0000256|RuleBase:RU361235};
DE EC=3.1.1.- {ECO:0000256|RuleBase:RU361235};
GN ORFNames=NEUTE2DRAFT_98970 {ECO:0000313|EMBL:EGZ76790.1};
OS Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ76790.1, ECO:0000313|Proteomes:UP000008513};
RN [1] {ECO:0000313|EMBL:EGZ76790.1, ECO:0000313|Proteomes:UP000008513}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT "Massive changes in genome architecture accompany the transition to self-
RT fertility in the filamentous fungus Neurospora tetrasperma.";
RL Genetics 189:55-69(2011).
CC -!- SIMILARITY: Belongs to the type-B carboxylesterase/lipase family.
CC {ECO:0000256|ARBA:ARBA00005964, ECO:0000256|RuleBase:RU361235}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; GL890999; EGZ76790.1; -; Genomic_DNA.
DR AlphaFoldDB; G4U8R1; -.
DR STRING; 510952.G4U8R1; -.
DR ESTHER; neucr-90C4.300; Fungal_carboxylesterase_lipase.
DR eggNOG; KOG4389; Eukaryota.
DR HOGENOM; CLU_006586_10_7_1; -.
DR Proteomes; UP000008513; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR002018; CarbesteraseB.
DR InterPro; IPR019826; Carboxylesterase_B_AS.
DR InterPro; IPR019819; Carboxylesterase_B_CS.
DR PANTHER; PTHR11559; CARBOXYLESTERASE; 1.
DR PANTHER; PTHR11559:SF360; CARBOXYLIC ESTER HYDROLASE; 1.
DR Pfam; PF00135; COesterase; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
DR PROSITE; PS00122; CARBOXYLESTERASE_B_1; 1.
DR PROSITE; PS00941; CARBOXYLESTERASE_B_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361235};
KW Reference proteome {ECO:0000313|Proteomes:UP000008513}.
FT DOMAIN 37..505
FT /note="Carboxylesterase type B"
FT /evidence="ECO:0000259|Pfam:PF00135"
FT REGION 569..603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 603 AA; 65813 MW; 349069D34E45730E CRC64;
MKDKKEKHVV ALWKKIPISD GWSTAVNVTY SEYVGEELGN GVSQWLGLRY AAPPVGALRF
APPQDPLSNS EPQAANKHGN WCVRRPGNSL TSEDCLFLDV YAPTKATTKS KLPVFVFIQG
GGFNDNANPN LNGTGLVKAS SNSIIVVTLN YRVGPYGFLT NGQQVVANNG LRDQRKALEW
VQKYISQFGG NPDHVVLGGA SAGAASVAYH MMADKDGNRK LFHAAAAESV SFGTVLTVQQ
AQYQYDNLMI RLGCARSDAA ASVACLRSKT QKEIADKDGD IPYPGSSNGP IYMWSPVIDG
DFVTDYPYSA FRNGNFIKNI PVIFGDDTNG GSGFVPDRIS SLGDSNQFIK DQFPAITLSQ
LDTLNMLYPN PNASICPRMG CWRGQAGSVY GEMRYMCPGL YLNDAFDNYN SQYSKGTSSW
AYRWNVEDRD QMASGLGVPH VVELNALFGP TNMWYTGQVP QSYFPGGTNA AAVQVMQSYW
VSFIRTFDPN TLRCCGSVEW KAWQSGDKAS AQHQRLLFGT GGKTAMEVIP FDEGLGLRCN
VAGSAWALNS RRIDGLAVPR FTQHSYGDCP SAVQTERRPR PCRVPRAAGN VSISKNRKAS
TLT
//
