ID G4UCC6_NEUT9 Unreviewed; 391 AA.
AC G4UCC6;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Di-copper centre-containing protein {ECO:0000313|EMBL:EGZ77183.1};
GN ORFNames=NEUTE2DRAFT_142723 {ECO:0000313|EMBL:EGZ77183.1};
OS Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ77183.1, ECO:0000313|Proteomes:UP000008513};
RN [1] {ECO:0000313|EMBL:EGZ77183.1, ECO:0000313|Proteomes:UP000008513}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT "Massive changes in genome architecture accompany the transition to self-
RT fertility in the filamentous fungus Neurospora tetrasperma.";
RL Genetics 189:55-69(2011).
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DR EMBL; GL890999; EGZ77183.1; -; Genomic_DNA.
DR AlphaFoldDB; G4UCC6; -.
DR STRING; 510952.G4UCC6; -.
DR eggNOG; ENOG502RM4B; Eukaryota.
DR HOGENOM; CLU_035914_0_1_1; -.
DR Proteomes; UP000008513; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF125; TYROSINASE COPPER-BINDING DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR PROSITE; PS00497; TYROSINASE_1; 1.
DR PROSITE; PS00498; TYROSINASE_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Monooxygenase {ECO:0000256|ARBA:ARBA00023033};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023033};
KW Reference proteome {ECO:0000313|Proteomes:UP000008513};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..391
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003469312"
FT DOMAIN 111..128
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00497"
FT DOMAIN 313..324
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00498"
SQ SEQUENCE 391 AA; 43445 MW; B73CC4AB49729564 CRC64;
MPSMARSLLF LVLAASSLVG ATGKDAVYKL QQTGKANLEL RLARSSTCTK ENLQIRREWG
DVSKAERREY IAAMLCLMSK PSQLDQTEYP GAKTRYDDFV AVHMNQTLTI HGTGSFLAWH
RYFTWSFERV LREECGYTGS QPYWNWGKWA SDPANSPLFD GSDTSLSGNG LKIDHEDTDY
YPAGPGGGCI YSGPFVNMTA RLGPLSPILK PAPAANPLPN GMGDNPRCVR RDITNYLSSR
YTRTEDMVTL IADSPDILTF QDRLQAVTAR PWEVEGTHNP AEHNGMPLMG IHASGHHTIG
GDPGGDFYTS PNDPAFFNHH AGIDRTWAIW QWLDLENRTE QIAGGTAMFD PVNSPRQTLD
DIVDLGVVGD QVWRIRDLVS TVDGPFCYTY E
//
