ID   G4UCT9_NEUT9            Unreviewed;       944 AA.
AC   G4UCT9;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   SubName: Full=ARM repeat-containing protein {ECO:0000313|EMBL:EGZ74754.1};
GN   ORFNames=NEUTE2DRAFT_82376 {ECO:0000313|EMBL:EGZ74754.1};
OS   Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ74754.1, ECO:0000313|Proteomes:UP000008513};
RN   [1] {ECO:0000313|EMBL:EGZ74754.1, ECO:0000313|Proteomes:UP000008513}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX   PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA   Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA   Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT   "Massive changes in genome architecture accompany the transition to self-
RT   fertility in the filamentous fungus Neurospora tetrasperma.";
RL   Genetics 189:55-69(2011).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the importin beta family. Importin beta-2
CC       subfamily. {ECO:0000256|ARBA:ARBA00038423}.
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DR   EMBL; GL891107; EGZ74754.1; -; Genomic_DNA.
DR   AlphaFoldDB; G4UCT9; -.
DR   STRING; 510952.G4UCT9; -.
DR   eggNOG; KOG2023; Eukaryota.
DR   HOGENOM; CLU_008136_1_0_1; -.
DR   OMA; AQEGAMS; -.
DR   Proteomes; UP000008513; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006606; P:protein import into nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR000357; HEAT.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR040122; Importin_beta.
DR   PANTHER; PTHR10527:SF3; FI21453P1-RELATED; 1.
DR   PANTHER; PTHR10527; IMPORTIN BETA; 1.
DR   Pfam; PF02985; HEAT; 1.
DR   Pfam; PF13513; HEAT_EZ; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008513};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   DOMAIN          32..100
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
FT   REGION          381..407
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        381..402
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   944 AA;  104977 MW;  7E269D871BB254EA CRC64;
     MAWQPSGENL KTLAQCLKDS LSAFNKAAQK QAEIMLNQAK ASPDINNYLA LIFSSSEPPQ
     EFPATAADWH VVRCAAALML KNNIKNNYNK IPEQSLALVK LAVPLGLQDK NSQIRSHAGT
     LATELINKGG IYGWPEFLPE LLKTLTNESG QVTPEAQEGA MAAMAKICED NAKMLEREHN
     GQRPINFLLP KLIQATRSAV PKVRAHALTA INVFTPRKSQ AMLNSIDDLL QHLFALAEDP
     SIDVRKQVCR AFVNLVETRP DKLLPHIEGL AKYIIAQQKG DDEDLATEAA EFWLTVGEHD
     NLWRALEPYI TDIIPVLLEC MVYSPEDIAI LGGASDDEDE EDREEDIKPQ FAKKKLTRAA
     NGNTAADMAK NGNAFEKVAS MEEDDDDLED GEIDDSESEG DENPDEKWTL RKCSAAALDV
     FARDFGGPVF TSILPYLQSN LKHADWSYRE AAVLALGAVA EGCMDVVVPH LPELVPYLVS
     LLDDEEPVVR QITCWTLGRY SAWAVSLVDQ AQKERYFLPM MDGILKKMLD KNKNVQEAGA
     SAMANLEEKA GKALEPYCGP IIQQYIRCFG KYKDKNMWVL YDCVQTLAEH IGPVLARPEL
     SNQLMPVLLD RWQKVGDESR ELFPLLECLS YVAMALGDAF TPYAEPIFGR CIRIIHQNLE
     QAMKAKTNTD LDQPDEDFLV TSLDLLSAII QALDNDKASK LVANVQPTFF ELMALCMGDQ
     SDAIQQSAYA LLGDCAKYVF EQLKPFLPNI MPVVIKRLDM DTILDEEVDN SFSVVNNACW
     SVGEIALQYK AGMAPFVPQL IQRCVDILSN PRVPGGVSEN AAIALGRLGL DNAELVAPHL
     GNFAEEFLDT MDDVDPSEEK ATALRGFTEM VTRNPQAMES VLLHYFSTIA NYQELSLQKP
     VLLELHEAFQ NVINVYKQII PGFGNFLMQM EAKDLELLQR LFAL
//