ID   G4UIY5_NEUT9            Unreviewed;       775 AA.
AC   G4UIY5;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 49.
DE   SubName: Full=Developmental regulator flbA {ECO:0000313|EMBL:EGZ73209.1};
DE   Flags: Fragment;
GN   ORFNames=NEUTE2DRAFT_60898 {ECO:0000313|EMBL:EGZ73209.1};
OS   Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ73209.1, ECO:0000313|Proteomes:UP000008513};
RN   [1] {ECO:0000313|EMBL:EGZ73209.1, ECO:0000313|Proteomes:UP000008513}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX   PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA   Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA   Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT   "Massive changes in genome architecture accompany the transition to self-
RT   fertility in the filamentous fungus Neurospora tetrasperma.";
RL   Genetics 189:55-69(2011).
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DR   EMBL; GL891217; EGZ73209.1; -; Genomic_DNA.
DR   AlphaFoldDB; G4UIY5; -.
DR   STRING; 510952.G4UIY5; -.
DR   eggNOG; KOG3589; Eukaryota.
DR   HOGENOM; CLU_013365_0_1_1; -.
DR   OMA; DPGMRYL; -.
DR   Proteomes; UP000008513; Unassembled WGS sequence.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   GO; GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.
DR   CDD; cd04450; DEP_RGS7-like; 1.
DR   CDD; cd08708; RGS_FLBA; 1.
DR   Gene3D; 1.10.167.10; Regulator of G-protein Signalling 4, domain 2; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR   InterPro; IPR000591; DEP_dom.
DR   InterPro; IPR016137; RGS.
DR   InterPro; IPR036305; RGS_sf.
DR   InterPro; IPR044926; RGS_subdomain_2.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR10845; REGULATOR OF G PROTEIN SIGNALING; 1.
DR   PANTHER; PTHR10845:SF192; RGS DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   Pfam; PF00610; DEP; 1.
DR   Pfam; PF00615; RGS; 1.
DR   SMART; SM00049; DEP; 2.
DR   SMART; SM00315; RGS; 1.
DR   SUPFAM; SSF48097; Regulator of G-protein signaling, RGS; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 2.
DR   PROSITE; PS50186; DEP; 1.
DR   PROSITE; PS50132; RGS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008513};
KW   Signal transduction inhibitor {ECO:0000256|ARBA:ARBA00022700}.
FT   DOMAIN          477..563
FT                   /note="DEP"
FT                   /evidence="ECO:0000259|PROSITE:PS50186"
FT   DOMAIN          600..747
FT                   /note="RGS"
FT                   /evidence="ECO:0000259|PROSITE:PS50132"
FT   REGION          33..157
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          182..268
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        33..123
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        138..157
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        217..232
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:EGZ73209.1"
SQ   SEQUENCE   775 AA;  84759 MW;  3B36F25D4519D08C CRC64;
     HRELLASPRP AGILAWVLAC EQVVCKEWVC SSSSRSTNSD SSSPVVALQA GNRSTGSTVN
     SSKSRSASSS ISTISSSANT GSAPATGTSG TASNTPSSHS SSSSSSSTTV SALAGNTIAK
     AKSNSVRDPV AKPPHPAVSG SQTRQQAHSH LSSLSVSSQR TGGIFALAAA ALDKTLAGLG
     EPRIRSRRSN GRLSAGPESP VGGPLLPGPD KSSRSRSASR SSPEDERHLA SSLVPRDPNP
     PSQPYSETDP NRPLPVRVSR VDNKMHQTSS RLLRMTDDDR PFTKDFKDLF STLIVSLLPL
     SAHRVRLTKV EHTFLSEDAI NNLGSLKFSQ SNRMPDPKDP SRIVTTTTTT TFSMAKDMAR
     SICQRFLEAR FIESADGRYQ QVYSMKGSVW QLTPKGISIL DRFCSRNGIQ QKQVAELIGN
     SLPQIVILER NPQTDKVLTD RALIEVIFRR FIGPNGFNIK QSVSSADSDS LSDYRDGLTG
     VKMAAERKVN GRTYRDTFTG KAATDWLMDC STAVDRRETI EIASLFVEYE LMEAVQQDKA
     HMQQNPGHHL FQPTKHAIYQ VTPKGKDLVN GALVRGRPSE SDGHSASRSV GIARDSNTQR
     LDKILNENSL RLLFRENLRE THCEENLAFY LDTDEFVRQC RAAIDLAQRS PNSAASLDGI
     KEIMAQAYGI YNAFLAPGSP CELNIDHQLR NNLATRMTKA VGQDVTMIDT LREVMALFED
     AQNAVFKLMA SDSVPKFLRN PKYEQTLRNY DFDSITPVHG QGRMVERSQS RSNRT
//