ID G4UKQ2_NEUT9 Unreviewed; 870 AA.
AC G4UKQ2;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 22-FEB-2023, entry version 39.
DE SubName: Full=CDC45-like protein {ECO:0000313|EMBL:EGZ73548.1};
GN ORFNames=NEUTE2DRAFT_165678 {ECO:0000313|EMBL:EGZ73548.1};
OS Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ73548.1, ECO:0000313|Proteomes:UP000008513};
RN [1] {ECO:0000313|EMBL:EGZ73548.1, ECO:0000313|Proteomes:UP000008513}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT "Massive changes in genome architecture accompany the transition to self-
RT fertility in the filamentous fungus Neurospora tetrasperma.";
RL Genetics 189:55-69(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CDC45 family.
CC {ECO:0000256|ARBA:ARBA00010727}.
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DR EMBL; GL891217; EGZ73548.1; -; Genomic_DNA.
DR AlphaFoldDB; G4UKQ2; -.
DR STRING; 510952.G4UKQ2; -.
DR eggNOG; KOG2475; Eukaryota.
DR HOGENOM; CLU_005871_3_0_1; -.
DR Proteomes; UP000008513; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0006270; P:DNA replication initiation; IEA:InterPro.
DR InterPro; IPR003874; CDC45.
DR PANTHER; PTHR10507; CDC45-RELATED PROTEIN; 1.
DR PANTHER; PTHR10507:SF0; CELL DIVISION CONTROL PROTEIN 45 HOMOLOG; 1.
DR Pfam; PF02724; CDC45; 2.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008513}.
FT REGION 196..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 714..819
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 202..221
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 223..238
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 721..774
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 775..814
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 870 AA; 96568 MW; 131A81B6C523C165 CRC64;
MYLPRQLISK LYLHLQNTRH PLSPPVLILV ALETDALCAC RILTQLLKHD YIPHKIQPVA
GYSDLERAGT ELVSPMMETR GGAGGVVVCL GVGGMVDLGT VLGLEPEGEE NTFGGVEVWV
IDSHRPWNLG NVFGGFPLEP ETQEARTFSA RTPIGVNGGR IERAYKPGKG GIIVMDDGDI
EDELSKERDA YLALVDMPEI EDDGRDLGDS DEDESETEED TGDTSVVAGR KRKSWSDFDE
DDDEDDRPRQ RRRSNSVNSP RRPQHRGLIS LRDDALFSSD ALEAPPAAQP PRGPSANTLR
RRLLRLRREN EGVLREYYRL GTSYSEPISS MMYSLASELG REDNDLLWLA IVGVTSMELY
GRSSAGIAVA ARRSDARISG WLGMRGARIR QLLRDEVRRL NPPEIGNGRV LPETTGIIPT
TARSPEDTSI RLSPEPKFLL IRHWSLYDSM LHSPYLFSRL KTWSEAGMKR LHKLLAKMGV
SLVQCKQSYA HMDMMLKREL RTKLLKYASL YNLDELVPTI DTDGKDRGGA KDGWGFVRSW
GWRATLSAQD VGVVVGALLE VGKNTTSADD LPAGPSQDLL DVDNNQSQSE EWIPRFWEAY
DALEDIEALK AGLPTAQYLH KAIFTTGTTI LKKKQISHLR AFRMCVVKDS PDATLFNHPG
ALTKLALWIG EALAEQEKEA TGGKLAHGGR GTPLVVASLD DKRGVYVVVG TGGGGGPDTK
FLDRESAKKR AEEKEAKANA KEMQRRIKDK IKAEKKEAKR KEKEEKKKAK SDAGGDEDEE
EDNEEDSDDD SDLSDSDSDD DDESDEDEDE LDQELERGYG LNKFGTAFQD VVAETNARVR
IDSFEHCVVE VKKEDLSGFL ESLSMKVVIG
//
