ID   G4UKZ4_NEUT9            Unreviewed;       876 AA.
AC   G4UKZ4;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 50.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EGZ73587.1};
GN   ORFNames=NEUTE2DRAFT_149613 {ECO:0000313|EMBL:EGZ73587.1};
OS   Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ73587.1, ECO:0000313|Proteomes:UP000008513};
RN   [1] {ECO:0000313|EMBL:EGZ73587.1, ECO:0000313|Proteomes:UP000008513}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX   PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA   Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA   Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT   "Massive changes in genome architecture accompany the transition to self-
RT   fertility in the filamentous fungus Neurospora tetrasperma.";
RL   Genetics 189:55-69(2011).
CC   -!- PATHWAY: Amino-acid biosynthesis; ergothioneine biosynthesis.
CC       {ECO:0000256|ARBA:ARBA00037882}.
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DR   EMBL; GL891217; EGZ73587.1; -; Genomic_DNA.
DR   AlphaFoldDB; G4UKZ4; -.
DR   SMR; G4UKZ4; -.
DR   STRING; 510952.G4UKZ4; -.
DR   eggNOG; ENOG502QS9T; Eukaryota.
DR   HOGENOM; CLU_006921_0_1_1; -.
DR   OMA; FKHWHPT; -.
DR   Proteomes; UP000008513; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   Gene3D; 3.90.1580.10; paralog of FGE (formylglycine-generating enzyme); 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR016187; CTDL_fold.
DR   InterPro; IPR024775; DinB-like.
DR   InterPro; IPR019257; MeTrfase_dom.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR017805; SAM_MeTrfase_EasF-type_put.
DR   InterPro; IPR005532; SUMF_dom.
DR   InterPro; IPR042095; SUMF_sf.
DR   NCBIfam; TIGR03439; methyl_EasF; 1.
DR   PANTHER; PTHR43397; ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1; 1.
DR   PANTHER; PTHR43397:SF1; ERGOTHIONEINE BIOSYNTHESIS PROTEIN 1; 1.
DR   Pfam; PF12867; DinB_2; 1.
DR   Pfam; PF03781; FGE-sulfatase; 2.
DR   Pfam; PF10017; Methyltransf_33; 1.
DR   SUPFAM; SSF56436; C-type lectin-like; 1.
PE   4: Predicted;
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008513};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          61..351
FT                   /note="Histidine-specific methyltransferase SAM-dependent"
FT                   /evidence="ECO:0000259|Pfam:PF10017"
FT   DOMAIN          382..513
FT                   /note="DinB-like"
FT                   /evidence="ECO:0000259|Pfam:PF12867"
FT   DOMAIN          569..700
FT                   /note="Sulfatase-modifying factor enzyme"
FT                   /evidence="ECO:0000259|Pfam:PF03781"
FT   DOMAIN          763..874
FT                   /note="Sulfatase-modifying factor enzyme"
FT                   /evidence="ECO:0000259|Pfam:PF03781"
FT   REGION          631..650
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          729..761
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   876 AA;  98858 MW;  9ABD8EA7B48726E0 CRC64;
     MPSAESMTPS SALGQLKATG QHVLSKLQQQ TSNADIIDIR RVAVEINLKT EITSMFRPKD
     GPRQLPTLLL YNERGLQLFE RITYLEEYYL TNDEIKILTK HATEMASFIP SGAMIIELGS
     GNLRKVNLLL EALDNAGKAI DYYALDLSRE ELERTLAQVP SYKHVKCHGL LGTYDDGRDW
     LKAPENINKQ KCILHLGSSI GNFNRSDAAT FLKGFTDVLG PNDKMLIGVD ACNDPARVYH
     AYNDKVGITH EFILNGLRNA NEILGETAFI EGDWRVIGEY VYDEEGGRHQ AFYGPTRDTM
     VMGELIRSHD RIQIEQSLKY SKEESERLWS TAGLEQVSEW TYGNEYGLHL LAKSRMSFSL
     IPSVYARSAL PTLDDWEALW ATWDVVTRHM LPQEELLEKP IKLRNACIFY LGHIPTFLDI
     QLTKTTKQAP SEPAHFCKIF ERGIDPDVDN PELCHAHSEI PDEWPPVEEI LTYQETVRSR
     LRGLYAHGIA NIPRNVGRAI WVGFEHELMH IETLLYMMLQ SDKTLPPTHI PRPDFEKLAK
     KAESGRVPNQ WFKIPAQEIT IGLDDPEDGT DINKHYGWDN EKPVRRVQVA AFQAQGRPIT
     NEEYAQYLLE KNIDKLPASW ARLDNEKIAN GTTNSVSGHH SNRTSKQQLP SSFLEKTAVR
     TVYGLVPLKH ALDWPVFASY DELAGCAAYM GGRIPTFEET RSIYAYADAL KKKKEAERQL
     GRTVPAVNAH LTNNGVEITP PSSPSSETPS ESSSPSGNNT TLITTEGLFS DLDGANVGFH
     NWHPMPVTSK GNTLLGQGEL GGVWEWTSSV LRKWEGFKPM ELYPGYTADF FDEKHNIVLG
     GSWATHPRIA GRKSFVNWYQ RNYPYAWVGA RVVRDL
//