ID   G4ULN2_NEUT9            Unreviewed;       849 AA.
AC   G4ULN2;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 41.
DE   SubName: Full=Acyltransferase-domain-containing protein {ECO:0000313|EMBL:EGZ73719.1};
GN   ORFNames=NEUTE2DRAFT_108607 {ECO:0000313|EMBL:EGZ73719.1};
OS   Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ73719.1, ECO:0000313|Proteomes:UP000008513};
RN   [1] {ECO:0000313|EMBL:EGZ73719.1, ECO:0000313|Proteomes:UP000008513}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX   PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA   Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA   Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT   "Massive changes in genome architecture accompany the transition to self-
RT   fertility in the filamentous fungus Neurospora tetrasperma.";
RL   Genetics 189:55-69(2011).
CC   -!- SIMILARITY: Belongs to the GPAT/DAPAT family.
CC       {ECO:0000256|ARBA:ARBA00007937}.
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DR   EMBL; GL891217; EGZ73719.1; -; Genomic_DNA.
DR   AlphaFoldDB; G4ULN2; -.
DR   STRING; 510952.G4ULN2; -.
DR   eggNOG; KOG3729; Eukaryota.
DR   HOGENOM; CLU_015023_0_0_1; -.
DR   OMA; ENMICKM; -.
DR   Proteomes; UP000008513; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008374; F:O-acyltransferase activity; IEA:InterPro.
DR   GO; GO:0044255; P:cellular lipid metabolic process; IEA:InterPro.
DR   CDD; cd07993; LPLAT_DHAPAT-like; 1.
DR   InterPro; IPR022284; GPAT/DHAPAT.
DR   InterPro; IPR045520; GPAT/DHAPAT_C.
DR   InterPro; IPR041728; GPAT/DHAPAT_LPLAT.
DR   InterPro; IPR002123; Plipid/glycerol_acylTrfase.
DR   PANTHER; PTHR12563:SF17; DIHYDROXYACETONE PHOSPHATE ACYLTRANSFERASE; 1.
DR   PANTHER; PTHR12563; GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE; 1.
DR   Pfam; PF01553; Acyltransferase; 1.
DR   Pfam; PF19277; GPAT_C; 1.
DR   SMART; SM00563; PlsC; 1.
DR   SUPFAM; SSF69593; Glycerol-3-phosphate (1)-acyltransferase; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW   ECO:0000313|EMBL:EGZ73719.1}; Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008513};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EGZ73719.1}.
FT   DOMAIN          216..343
FT                   /note="Phospholipid/glycerol acyltransferase"
FT                   /evidence="ECO:0000259|SMART:SM00563"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          799..849
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        818..849
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   849 AA;  95108 MW;  7366185A3A67F745 CRC64;
     MADEQDGRDD SPAQVEDSAP DLRILGDRIT LQPSGFVAPS KGSLGDEKEE ALMKNMARFR
     SEPLQFLREV SLYVSGTGWR AYDDVIGQPV FYPGYTEHIK SQVMSATLLQ AKIAQLAEMR
     LAVEEKQGLL NKNDRNFETK RNQRRSVLVQ SLQEVAEQLT DNMVCKMESK TFIRGAYYMV
     TQLLLRAYHQ GIHVSSEEVL RLRNVAREAE KKGQSIIFLP CHRSHVDYVA SQLLCYRLGL
     TMPVVVAGDN LNFPLVGNFL QHAGAMFIRR SFGDDQLYTT LVQAYIDVLL QGGYNFECFI
     EGGRSRTGKL LPPKFGILSF ILDSILSGRV QDTVICPVSY QYDKVVETEG YVTELLGVPK
     KKENLADFLS GGSSVLSLRL GRVDVRFHEP WSLRGFIDEQ VIRLSKVPSS INWKDMKNPI
     VRQKLLRTLG YKVLADINDV SVVMPTALIG TVLLTLRGRG VGRAELIRRV EWLTARVRAK
     GGRVAHFGNT PVSDVIERGL EVLGKDLVGV AEGLAETTYY AVDRFQLSFY RNMTIHLFIS
     EALVAAALYT RVKRGGGPAI QDIPYQDLHN QVLFLSSLFR GEFIYSGEGL AVNLEKTLMG
     LEADNVVFLE RDELTGAITK VGLSDAERAA GRENYDFYCF LIWPFIEASW LASVSIMGLT
     PPLGQKDDIW IQFSKAQESA QLLGKTLYHQ GDLSYFEAVN KETLKNSYQR FEEEGIIQVV
     KSKDPKVPPR MRLAPEWRPA RDEISGVLIA SGRLWDFTEK IASSRREGKN RRDGATVSTR
     VVRLTDDLGQ KLFEEAIAGT DGSKKGKGKG KGKGKGAAPA RLSREEEKIL TADLKESKRR
     RTLENRAHL
//