ID G4UST3_NEUT9 Unreviewed; 798 AA.
AC G4UST3;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE SubName: Full=DUF726-domain-containing protein {ECO:0000313|EMBL:EGZ70659.1};
GN ORFNames=NEUTE2DRAFT_159010 {ECO:0000313|EMBL:EGZ70659.1};
OS Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ70659.1, ECO:0000313|Proteomes:UP000008513};
RN [1] {ECO:0000313|EMBL:EGZ70659.1, ECO:0000313|Proteomes:UP000008513}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT "Massive changes in genome architecture accompany the transition to self-
RT fertility in the filamentous fungus Neurospora tetrasperma.";
RL Genetics 189:55-69(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the TMCO4 family.
CC {ECO:0000256|ARBA:ARBA00009824}.
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DR EMBL; GL891247; EGZ70659.1; -; Genomic_DNA.
DR AlphaFoldDB; G4UST3; -.
DR eggNOG; KOG2385; Eukaryota.
DR HOGENOM; CLU_007407_1_0_1; -.
DR OMA; KDIHWED; -.
DR Proteomes; UP000008513; Unassembled WGS sequence.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR007941; DUF726.
DR PANTHER; PTHR17920:SF3; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR17920; TRANSMEMBRANE AND COILED-COIL DOMAIN-CONTAINING PROTEIN 4 TMCO4; 1.
DR Pfam; PF05277; DUF726; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000008513};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT REGION 1..85
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 143..200
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 241..264
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 41..57
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 163..198
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 798 AA; 87471 MW; 53E738F6D5B4345C CRC64;
MAALKNAPAP AVTVRSSKAL GLKTCHPVPP GLPSPKDAAE AASPTSPTLS HTASDDSTIA
DMPPGGRPRH NPPKREADFS SLLSPQEKND LTSLITRTTD VMQKHFTHVY DSAGLVDDAP
SVRNKFWSGL PAHLRDFSIT KPLPVETQLQ NPKKRTKGKT SRSQKENGNM ARDTKNSTGA
ALQPANPSNL NIQRAPEQDN DKTIGPYLQE LKKEAMLHFK KWQTAVHKRM GDISVKRAGD
ANFNSTVPNN RRGRNRPNGV STSNIESDPV LMQLYPPIPS TLCYWPLERR LLVLHALLLL
LLSLEHYSAY TRVLLLHITS SLNLPLRVLV DDEVRVAKAI AWMAKDINPE ELIQKRIEEC
AGKPSRRWRH GLASMAGISS FGIPGHLAPP LVAAGIGSVN GGFGLGPTAS AGILGSTGES
AFVVGALLGI YNARTSVKLM EQCTKEIQDF AFIPMRGSIG EDGEIGKIQP DARRLRVVLA
ISGWLTDESD VTNPWRALGQ ANEVYAVRWE VDSLSKMGTA LETVVRSSAW SMAKKEIIAR
TSEPPFNIPK CNLSRRANKH GPVFTSMTES LWPLGLLKIN KIIDNPWSVG MVRADKAGAL
LADAIMNKAH GERGVTLIGY SLGARAIYVC LMVLAERRAF GLVENAVMMG TPAPSEARVW
CTMRSVVSGR LVNVFSENDY LLGFLYRTSS IQFGVAGLQR IEGLDGVENV DVSAKVSGHL
RYQYLAGSIL KHINWEDINQ EQVSRDEAAM VAAEERVRER EKKRDAVERG IVVIDKAKEA
AKNDPGIIRT RMRKKNKR
//
