ID   G4UTU4_NEUT9            Unreviewed;      1299 AA.
AC   G4UTU4;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 52.
DE   SubName: Full=150 kDa dynein-associated polypeptide ro-3 {ECO:0000313|EMBL:EGZ70039.1};
GN   ORFNames=NEUTE2DRAFT_112499 {ECO:0000313|EMBL:EGZ70039.1};
OS   Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ70039.1, ECO:0000313|Proteomes:UP000008513};
RN   [1] {ECO:0000313|EMBL:EGZ70039.1, ECO:0000313|Proteomes:UP000008513}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX   PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA   Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA   Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT   "Massive changes in genome architecture accompany the transition to self-
RT   fertility in the filamentous fungus Neurospora tetrasperma.";
RL   Genetics 189:55-69(2011).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000256|ARBA:ARBA00004245}.
CC   -!- SIMILARITY: Belongs to the dynactin 150 kDa subunit family.
CC       {ECO:0000256|ARBA:ARBA00011010}.
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DR   EMBL; GL891247; EGZ70039.1; -; Genomic_DNA.
DR   STRING; 510952.G4UTU4; -.
DR   eggNOG; KOG0971; Eukaryota.
DR   HOGENOM; CLU_002523_1_1_1; -.
DR   OMA; LFEMEPV; -.
DR   Proteomes; UP000008513; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR   GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR   Gene3D; 2.30.30.190; CAP Gly-rich-like domain; 1.
DR   InterPro; IPR036859; CAP-Gly_dom_sf.
DR   InterPro; IPR000938; CAP-Gly_domain.
DR   InterPro; IPR022157; Dynactin.
DR   PANTHER; PTHR18916; DYNACTIN 1-RELATED MICROTUBULE-BINDING; 1.
DR   PANTHER; PTHR18916:SF6; DYNACTIN SUBUNIT 1; 1.
DR   Pfam; PF01302; CAP_GLY; 1.
DR   Pfam; PF12455; Dynactin; 1.
DR   SMART; SM01052; CAP_GLY; 1.
DR   SUPFAM; SSF74924; Cap-Gly domain; 1.
DR   PROSITE; PS00845; CAP_GLY_1; 1.
DR   PROSITE; PS50245; CAP_GLY_2; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Dynein {ECO:0000256|ARBA:ARBA00023017};
KW   Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008513}.
FT   DOMAIN          28..70
FT                   /note="CAP-Gly"
FT                   /evidence="ECO:0000259|PROSITE:PS50245"
FT   REGION          72..249
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          257..527
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          981..1074
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1099..1126
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        72..148
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        159..204
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        235..249
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1299 AA;  145007 MW;  D8F143864FA47BFC CRC64;
     MSELGVAVGQ KIELADGSGR TAFVRYVGET AFAPGTWVGI ELDEPSGKND GSVQGERYFN
     CEMGYGMFVR PTTFNSPTRS PTKQLATASS SGNPSRSGTP STTTKPAGPT TRTRPSLSTS
     RHSMGPPLTP TTRTTRKPSV SSVGTRPSIG ATRAVGGRAS MSARSSTNRL SDPRESTGSV
     SSVGKSGFKR GSASPRSSDE DLSASPVPAS PVHQKTAALE KLTAPGAGNG GGGASPGATS
     PNLKATTITP RSSITNTATM NKEIEDLKAK LKVLEKKRME DREKLNSLEK VKAERDKFER
     IIQTLQIKYQ PQQQEIQDLK RQLKEAENRL YNVEELQAEH DTAMELATLD REMAEETAEV
     LKVELDALKQ KNEELELEVE VLREENSEFT NGMSPEERAS TGWLQMERNN ERLREALIRL
     RDITQQQEEE LKDQIKSMEE DLREFETIKE QHTTAKEKLA QTEAIVEDLR EQLNNALGAE
     EIIESLTEQT MNQSEEIKEL RAVIDDLESL KEINDELEIN HVQNEKEMQE EIDLKDSIIA
     EQFRQANLQR ESLEDMEYTL SRFRELVTSL QSDLEDMRAS HAVTENESEQ LNSRSRAMLD
     LNMKLQISAS KAQVKTIDLE LRRMEAQEAE QHLEIVKLFL PDTYQSDRDS VLALLRFKRL
     AFKANLLNGF IKERVNGQPH PGHEDDIFDG CDAIDKLTWV SAMCDRFVNA ISHCSLEQFS
     RYEGALYELE PVERALNGWI DGLRRDDLKE KQCADELKRT IALMTHLGEV HISNDLESFA
     DDVHMKALLM QSHLESAAIS VNSLKAMVQR VIPPSGEDDE LAQYFSKRAE AVVSQTRSAK
     VIAGKTVRAL EDLKTRSLSL TPDTLEAFEQ SETATRDLAN MARQIGLDLH AFLHEEGRTE
     PYNYMEVQSC IQRSAQASSP TASSPESDLF NTYLSYLRNA TSTIFDLASL ASDLAQTQEF
     DRTPAPWILR SAELKAAKTV APDIDDELRR LRDDIAEARR SIAVREEMLS TAQVKIETLE
     SRMRDANAKA ARIVDLESDL QAAKKEAAQL QEDMEKQDRE LKALESDRDK WKKIASESRV
     VVADGSGVGV DNKASAERAV ATAREMDALK KEIEALQAAV RYLREDSRRA RLKEQGDYEW
     LAEPLVKKKP SVQEQRKQLV KKEGKAVLGE LVKLVSGAKV FDLGSLPEKA EDRLKWRPAK
     TTPGWWVAKQ MEDWEALKEW EGSVKGRVRE LGGASGSKKA EREEEAKRMV RRTAAAKLQI
     RLPGMESKVG HGGGGGGRRV QIVGSREWES LQGRLAVVV
//