ID   G4UX63_NEUT9            Unreviewed;       449 AA.
AC   G4UX63;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   RecName: Full=Transcription initiation factor TFIID subunit 8 {ECO:0000256|ARBA:ARBA00017307};
GN   ORFNames=NEUTE2DRAFT_114704 {ECO:0000313|EMBL:EGZ68820.1};
OS   Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX   NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ68820.1, ECO:0000313|Proteomes:UP000008513};
RN   [1] {ECO:0000313|EMBL:EGZ68820.1, ECO:0000313|Proteomes:UP000008513}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX   PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA   Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA   Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT   "Massive changes in genome architecture accompany the transition to self-
RT   fertility in the filamentous fungus Neurospora tetrasperma.";
RL   Genetics 189:55-69(2011).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the TAF8 family.
CC       {ECO:0000256|ARBA:ARBA00008767}.
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DR   EMBL; GL891258; EGZ68820.1; -; Genomic_DNA.
DR   AlphaFoldDB; G4UX63; -.
DR   STRING; 510952.G4UX63; -.
DR   eggNOG; ENOG502SG72; Eukaryota.
DR   HOGENOM; CLU_026584_1_0_1; -.
DR   OMA; HDWIYAL; -.
DR   Proteomes; UP000008513; Unassembled WGS sequence.
DR   GO; GO:0005669; C:transcription factor TFIID complex; IEA:InterPro.
DR   GO; GO:0046982; F:protein heterodimerization activity; IEA:InterPro.
DR   Gene3D; 1.10.20.10; Histone, subunit A; 1.
DR   InterPro; IPR006565; BTP.
DR   InterPro; IPR009072; Histone-fold.
DR   InterPro; IPR037818; TAF8.
DR   InterPro; IPR019473; TFIID_su8_C.
DR   PANTHER; PTHR46469; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8; 1.
DR   PANTHER; PTHR46469:SF1; TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 8; 1.
DR   Pfam; PF07524; Bromo_TP; 1.
DR   Pfam; PF10406; TAF8_C; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008513};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          124..195
FT                   /note="Bromodomain associated"
FT                   /evidence="ECO:0000259|Pfam:PF07524"
FT   DOMAIN          248..273
FT                   /note="Transcription factor TFIID subunit 8 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10406"
FT   REGION          68..99
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          312..332
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   449 AA;  49068 MW;  FB40AB4889FCEE1E CRC64;
     MQVEGAPAPG LIDSSRSSVR DFPNIFNHQI NFPLHHPPHG RVTIFCQHGI ATDINTIDKT
     YHIAPANNKP LAMATDSRKR PVDAEGAQPS QPKRPKTNTS IRTILAVDAI GNSSKATTAP
     TPDGLAKNGL RRSIALALET VGFDGATSEA IESFTIMTET YLHSLTEEVK VFANAARRSY
     PIPKDFENTL KRFNLTPTAL YSHRKPPIPK KQRQPVWEDL PLDAAIPTDL PVLDPELDGA
     ADKAAKNYIP SSFPSFPSVH TYKYTPESVE AATTAQHSIM TDTQATVTMT QTQTMVESQA
     AAATAAVAAQ QSQLPTKIPQ RPLAPDEIPR GDPKKIREAA AKEAKAGEQA LRRLMRASKI
     AKQKDVSATA QRDPSRRERY ALWEAAMREL VEDDTKAKGR EVAPASMHSQ QGRVEIADHS
     MIVNAEKGYY RKEVARPGVR KLAGELAGK
//