ID G4UYH8_NEUT9 Unreviewed; 358 AA.
AC G4UYH8;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE SubName: Full=NAD(P)-binding protein {ECO:0000313|EMBL:EGZ69087.1};
GN ORFNames=NEUTE2DRAFT_115264 {ECO:0000313|EMBL:EGZ69087.1};
OS Neurospora tetrasperma (strain FGSC 2509 / P0656).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Sordariomycetidae; Sordariales; Sordariaceae; Neurospora.
OX NCBI_TaxID=510952 {ECO:0000313|EMBL:EGZ69087.1, ECO:0000313|Proteomes:UP000008513};
RN [1] {ECO:0000313|EMBL:EGZ69087.1, ECO:0000313|Proteomes:UP000008513}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=strain FGSC 2509 / P0656 {ECO:0000313|Proteomes:UP000008513};
RX PubMed=21750257; DOI=10.1534/genetics.111.130690;
RA Ellison C.E., Stajich J.E., Jacobson D.J., Natvig D.O., Lapidus A.,
RA Foster B., Aerts A., Riley R., Lindquist E.A., Grigoriev I.V., Taylor J.W.;
RT "Massive changes in genome architecture accompany the transition to self-
RT fertility in the filamentous fungus Neurospora tetrasperma.";
RL Genetics 189:55-69(2011).
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DR EMBL; GL891258; EGZ69087.1; -; Genomic_DNA.
DR AlphaFoldDB; G4UYH8; -.
DR eggNOG; KOG1196; Eukaryota.
DR HOGENOM; CLU_026673_29_2_1; -.
DR OMA; EEKCRYA; -.
DR Proteomes; UP000008513; Unassembled WGS sequence.
DR GO; GO:0016628; F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR CDD; cd05288; PGDH; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013149; ADH-like_C.
DR InterPro; IPR041694; ADH_N_2.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR045010; MDR_fam.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR PANTHER; PTHR43205:SF42; ALCOHOL DEHYDROGENASE, ZINC-CONTAINING (AFU_ORTHOLOGUE AFUA_7G04530); 1.
DR PANTHER; PTHR43205; PROSTAGLANDIN REDUCTASE; 1.
DR Pfam; PF16884; ADH_N_2; 1.
DR Pfam; PF00107; ADH_zinc_N; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000008513}.
FT DOMAIN 29..345
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 358 AA; 39205 MW; 50555BFDC07C20FE CRC64;
MFHHTHGYKS HSLQLELVHR PTGPIIPSHT FRVSAVPAPV PSDLNEGDLL LETLYISLDP
AMRGWLDDVR SYVPPVQIGE VMRAFCICRV LASRSPKAAA GDIVTAMNGI REIGILSDRH
IEKPAFLPPG GKTTDLLGVL GMTGLTAYFG MMKIGNVKRG DTVVVSAAAG ATGSVAVQIA
RIQGAKRVVG TAGSDEKCRW LVEEGGADVA LNYKDPEFRR KFREATPDFV DVYFDNVGGE
QLNMALARAN RGARFVMCGG ISQYNAEHKQ GPKNINNVIT MRIRMEGFIV FDYKDEYPTA
LGQLAQWLAE GKLKRKETIL KGGVRVADEG MVQLYKGGNI GKLLIEVKNP DEERQSRL
//
