ID   G4VAX0_SCHMA            Unreviewed;       477 AA.
AC   G4VAX0;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   24-JAN-2024, entry version 56.
DE   RecName: Full=Rab9 effector protein with kelch motifs {ECO:0000256|ARBA:ARBA00039295};
OS   Schistosoma mansoni (Blood fluke).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6183 {ECO:0000313|Proteomes:UP000008854, ECO:0000313|WBParaSite:Smp_025700.1};
RN   [1] {ECO:0000313|Proteomes:UP000008854}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Puerto Rican {ECO:0000313|Proteomes:UP000008854};
RX   PubMed=22253936; DOI=10.1371/journal.pntd.0001455;
RA   Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A.,
RA   De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C.,
RA   Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J.,
RA   Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A.,
RA   Zerlotini A., Dunne D.W., Berriman M.;
RT   "A systematically improved high quality genome and transcriptome of the
RT   human blood fluke Schistosoma mansoni.";
RL   PLoS Negl. Trop. Dis. 6:E1455-E1455(2012).
RN   [2] {ECO:0000313|WBParaSite:Smp_025700.1}
RP   IDENTIFICATION.
RC   STRAIN=Puerto Rican {ECO:0000313|WBParaSite:Smp_025700.1};
RG   WormBaseParasite;
RL   Submitted (DEC-2018) to UniProtKB.
CC   -!- FUNCTION: Rab9 effector required for endosome to trans-Golgi network
CC       (TGN) transport. {ECO:0000256|ARBA:ARBA00037224}.
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DR   RefSeq; XP_018648414.1; XM_018793953.1.
DR   AlphaFoldDB; G4VAX0; -.
DR   STRING; 6183.G4VAX0; -.
DR   EnsemblMetazoa; Smp_025700.1; Smp_025700.1; Smp_025700.
DR   GeneID; 8354114; -.
DR   KEGG; smm:Smp_025700; -.
DR   WBParaSite; Smp_025700.1; Smp_025700.1; Smp_025700.
DR   CTD; 8354114; -.
DR   eggNOG; KOG0379; Eukaryota.
DR   HOGENOM; CLU_045313_0_0_1; -.
DR   InParanoid; G4VAX0; -.
DR   OMA; FIHGGMD; -.
DR   OrthoDB; 5474681at2759; -.
DR   PhylomeDB; G4VAX0; -.
DR   Proteomes; UP000008854; Unassembled WGS sequence.
DR   Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   PANTHER; PTHR46647; RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS; 1.
DR   PANTHER; PTHR46647:SF1; RAB9 EFFECTOR PROTEIN WITH KELCH MOTIFS; 1.
DR   Pfam; PF13418; Kelch_4; 1.
DR   SUPFAM; SSF117281; Kelch motif; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008854};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
SQ   SEQUENCE   477 AA;  53796 MW;  54A50EBC9AE84D32 CRC64;
     MHKLLEKLSI RGSWCKVSYI LEGKSPLARV GHSTHAIRVE CGDTGNRPLI IMIGGADASG
     VFDEAYILDI TSFKWYTVDL EQTIDFPGLG RYEHSSAILN NQELIIFGGA TNTGPLSQLL
     RLQIHCLSTP ENPSINEEER ITASLTQDRI HTDIQQFIYH PRTQNSSVSL TEYNQLIVFS
     GGNVGSQPVS DDKVYMYDSE INSWNIIPVE GLPPCSRLGH LMLYEFPYQL TNSNYERIPK
     GKLYIHGGMV NEKLLDDIYV LQFTNQADNN LHFKGIWSKL YPTDNLSPLT ISHDNAENEC
     EYLESEGIES TKTPSPGPRA AHGGTILTNK IYGQDTSKIL IFGGLSLNGA LNDMFCFDTS
     TKQWTEIKYE TSVLPSPRLD FAYCTFSLIV KKDTKENSMK IIFKSPKDNQ YHDDIVNTDE
     YEDEDQYCQE YLFIHGGMDT HGVMFDDSYL ILLSEYQLSN PLNVQTIILQ SSSHGKC
//