GenomeNet

Database: UniProt
Entry: G4VJZ1_SCHMA
LinkDB: G4VJZ1_SCHMA
Original site: G4VJZ1_SCHMA 
ID   G4VJZ1_SCHMA            Unreviewed;      1531 AA.
AC   G4VJZ1;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   31-JUL-2019, entry version 51.
DE   SubName: Full=Putative ribonuclease III {ECO:0000313|EMBL:CCD79999.1};
DE            EC=3.1.26.3 {ECO:0000313|EMBL:CCD79999.1};
GN   ORFNames=Smp_142510.1 {ECO:0000313|EMBL:CCD79999.1};
OS   Schistosoma mansoni (Blood fluke).
OC   Eukaryota; Metazoa; Platyhelminthes; Trematoda; Digenea; Strigeidida;
OC   Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6183 {ECO:0000313|Proteomes:UP000008854};
RN   [1] {ECO:0000313|Proteomes:UP000008854}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Puerto Rican {ECO:0000313|Proteomes:UP000008854};
RX   PubMed=22253936; DOI=10.1371/journal.pntd.0001455;
RA   Protasio A.V., Tsai I.J., Babbage A., Nichol S., Hunt M., Aslett M.A.,
RA   De Silva N., Velarde G.S., Anderson T.J., Clark R.C., Davidson C.,
RA   Dillon G.P., Holroyd N.E., LoVerde P.T., Lloyd C., McQuillan J.,
RA   Oliveira G., Otto T.D., Parker-Manuel S.J., Quail M.A., Wilson R.A.,
RA   Zerlotini A., Dunne D.W., Berriman M.;
RT   "A systematically improved high quality genome and transcriptome of
RT   the human blood fluke Schistosoma mansoni.";
RL   PLoS Negl. Trop. Dis. 6:E1455-E1455(2012).
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   -----------------------------------------------------------------------
DR   EMBL; HE601628; CCD79999.1; -; Genomic_DNA.
DR   RefSeq; XP_018652601.1; XM_018797572.1.
DR   EnsemblMetazoa; Smp_142510.1; Smp_142510.1:pep; Smp_142510.
DR   GeneDB; Smp_142510.1:pep; -.
DR   GeneID; 8351918; -.
DR   KEGG; smm:Smp_142510.1; -.
DR   CTD; 8351918; -.
DR   eggNOG; KOG1817; Eukaryota.
DR   eggNOG; COG0571; LUCA.
DR   InParanoid; G4VJZ1; -.
DR   KO; K03685; -.
DR   OrthoDB; 935825at2759; -.
DR   PhylomeDB; G4VJZ1; -.
DR   Proteomes; UP000008854; Chromosome 5.
DR   GO; GO:0004525; F:ribonuclease III activity; IEA:UniProtKB-EC.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006396; P:RNA processing; IEA:InterPro.
DR   GO; GO:0016075; P:rRNA catabolic process; IEA:InterPro.
DR   CDD; cd00048; DSRM; 1.
DR   CDD; cd00593; RIBOc; 2.
DR   Gene3D; 1.10.1520.10; -; 3.
DR   HAMAP; MF_00104; RNase_III; 1.
DR   InterPro; IPR014720; dsRBD_dom.
DR   InterPro; IPR011907; RNase_III.
DR   InterPro; IPR000999; RNase_III_dom.
DR   InterPro; IPR036389; RNase_III_sf.
DR   Pfam; PF00035; dsrm; 1.
DR   Pfam; PF00636; Ribonuclease_3; 2.
DR   SMART; SM00358; DSRM; 1.
DR   SMART; SM00535; RIBOc; 2.
DR   SUPFAM; SSF69065; SSF69065; 2.
DR   PROSITE; PS50137; DS_RBD; 1.
DR   PROSITE; PS00517; RNASE_3_1; 2.
DR   PROSITE; PS50142; RNASE_3_2; 2.
PE   3: Inferred from homology;
KW   Complete proteome {ECO:0000313|Proteomes:UP000008854};
KW   Hydrolase {ECO:0000313|EMBL:CCD79999.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008854};
KW   RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00266}.
FT   DOMAIN      829   1010       RNase III. {ECO:0000259|PROSITE:PS50142}.
FT   DOMAIN     1062   1191       RNase III. {ECO:0000259|PROSITE:PS50142}.
FT   DOMAIN     1218   1292       DRBM. {ECO:0000259|PROSITE:PS50137}.
FT   REGION      223    256       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      306    360       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION      383    408       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   REGION     1483   1507       Disordered. {ECO:0000256|SAM:MobiDB-
FT                                lite}.
FT   COMPBIAS    345    360       Polar. {ECO:0000256|SAM:MobiDB-lite}.
SQ   SEQUENCE   1531 AA;  175260 MW;  46F5778481472552 CRC64;
     MTGSRFPLDK RIIYISPKDL SSLPTDGPIY VLSTTENPEP DPLASCSSTQ FGAPSQNPSS
     VTCSTFGSAS TSSTNSSNYY NNTLVPYSVP YHANIPYPPS VVSTNLIPPY GFCPPLQLPP
     FVGSQPVSWV TSAFQNHTLY PPSANVFAAS GQYIHPYQNF PTFQSNVPST LYFQTFNPYK
     PPPPLSLPQV TSKPSNTVLI NSSTAVTNNN TVTYVASTMN TNNTKNSCAF SRSNEENGSS
     EPINSKSGST SSSKQSHPLR YTKLIYASEP DYFAFDSSTG SYVATRQFID LEDRFENEVV
     ARRHRVTLND PVRQPPERPT LSDSEHRRNS RASHLHRSKK STHKSDTVNS MFDNNSDNDD
     DYLAVISDNT ETSKEVCLST ESKNKNLSID HTKHSKSSPS SSNSHRHLRK NEVNNYESIC
     TSNNSNNNTN NNSILNSDCH TVNGHSIGQR SIRQQREVAH KIEHPNRLHP DIWHNEANEF
     NDGPACSCKP KYRIGPLHNQ YEGEQPIPLC IPESNNRNRL YHYRVIISPT TNFVQPIPSK
     ITHNEHDYLF DGFSLFMHYR LDKPPPCQVL RFNLLYDIFP IEEEFPQYFT VRSLDLLTQY
     VFIELLELLD LNWKPYGAKE SCNVIHLMPR FIRIFDNNTV IGELLPVHVI MRHWLEEALT
     PVINMMELSS IQHMTTIEWS NHIANLRGTL ACFPGKKPST IRIDQLDRQS VTGQSNQTIL
     IYPLIVHMTY TPMKLSLTRE PKYKCVLKNF MKLQYLMMNK PRISTSDRVQ LVQLANELEE
     MEHSGVHRRE ITVEISCEGF YRTGMRPDIP QYALNLVSLI AHLRFHKSLE SLENRLGYTF
     NDKSLLHQSL THPSYRRTNF GTNQDHFQNS LVSCGPRILE YGDKLELYKA WRKKGLTKMI
     QVMSFLPKMH EERSNIYGNE RLEFLGDAVV EVISSIHLFF MFPELSEGHL DAYRQAIVQN
     QHLAELAVRL GIHKYLLYTH SVDFCYDSTF IYARSDAFEA LMAAITLDAG LDIVDRIFGA
     VLFGDDERIH RVWVQIPLHP LQSQCPEGDR SWATKVPMLK KLCTLEDTLG IKFKHLRVLA
     RAMTIRKTGF NFYTLGDNQR LEFLGDSLLK YVSTDYLFRH FPRHHEGHLS LLKNSLVNKY
     TQASVCSELG LEHYVIHRNK NDNCNNSQNQ NVKYRADLLE AFIGALFVDK DLAWVERFCQ
     ICFWPRLVEF ILKQEWNDAK SKLQQCCLTF RSLNEDPEIA HYKVLEHSGP TNQRVYRVGV
     YFRGQRLATG EGRSVQQAQM EAAKKALELH QDTFRQLDFQ RSVISKRYKQ PYINKILDQV
     QNWDEQLVDY FISDRPTSTT IMSTLTSNTT ITNDNNNTPI NTDKMSNSGN RTMKRSFLSN
     HNNDTNSEEL LLLYSSAKRR CFDKNISNQD SCTNKKTSYL SSVSSTSRFD TSPSICLSSQ
     TSTSTNDSGE DGVAIIDSKT ERLNTVKDIE KKNEELFAVF DNNDKNSHDN NVVENNREEN
     DEEEEGEIIE DDDCCDDITN EKYCKCKLFL K
//
DBGET integrated database retrieval system