ID G4YJ98_PHYSP Unreviewed; 1045 AA.
AC G4YJ98;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE SubName: Full=Patched family protein {ECO:0000313|EMBL:EGZ29432.1};
GN ORFNames=PHYSODRAFT_322952 {ECO:0000313|EMBL:EGZ29432.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ29432.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ29432.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ29432.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH159151; EGZ29432.1; -; Genomic_DNA.
DR RefSeq; XP_009516707.1; XM_009518412.1.
DR AlphaFoldDB; G4YJ98; -.
DR EnsemblProtists; EGZ29432; EGZ29432; PHYSODRAFT_322952.
DR GeneID; 20644877; -.
DR KEGG; psoj:PHYSODRAFT_322952; -.
DR InParanoid; G4YJ98; -.
DR OMA; WWFDVES; -.
DR PHI-base; PHI:11788; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR45727; NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1; 1.
DR PANTHER; PTHR45727:SF2; NPC INTRACELLULAR CHOLESTEROL TRANSPORTER 1; 1.
DR Pfam; PF02460; Patched; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Lipid transport {ECO:0000256|ARBA:ARBA00023055};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00023055}.
FT TRANSMEM 314..333
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 345..369
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 375..396
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 436..459
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 465..493
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 848..867
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 874..896
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 908..931
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 952..979
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 991..1014
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 313..493
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 1045 AA; 115363 MW; 8F983D249C17732C CRC64;
MARAFYRLGA LCSGSPVLMA LAALLCGGVL CLGLLNMRLQ TDPQGLWVPP RSVAAREQAR
FDELFGPFFR VQQLIFYADS DSDGLSATCD ASRDLVQRRF LLQMAKVQAQ IADAAVTVQG
DGAQGKVTLS LEDFCYRPIR GKGCLVTSPF QYWLGNASLL EGDPDIKLTT ACQTTDPQLQ
ERAPCMDQNG VPVMRDVVFG GLSRDDCHQN PDPCGEATPQ AQALVVTFLL NNRPENETYT
RYVEQWEQQA FLKIAAQAAE ALKPSSTANK SDEFIWDSVQ DQELADVGVD GMRLSYMAER
SVADSLVVQT NQNAFIVVVS YLVMFLYVSA SLGKFTDPVR SRFGLGLTGI LIVLLSLGAA
MGVSCAILQM EVTMITLEVV PFLVLAIGVD NMFILTNEFD RLAALRGLAT LDTRRNTRDR
AEDELLMLKQ VLGETMVNVG PSIVVAAVAE TLAFLVGALT RIPALTSFCV VAALAVAADF
ALQMTWFASA LVLDARRVRA RRYDLFPWMK QKLTLTPPTK GKRRIESKIH YQYDLLVDES
ERSDEPAARV SSTGTLQRFV EKTYIPFLLR RSTKVLVLVT ALSVVTLSAF GSSELPLGLE
QELAVPTDFY LHEYFKKQTA LGEAGPPAYV VLDSDVDYTD ARLQQDVNVL LDQLSGLRQY
IQLPVCSWLH TFNQWRQMRF FLQDKIKQGQ CDCPVQPMDP FPYELANVGV EDPSGDVDLF
LAPEYGYGAL ATAHVTPNAL FYPLVKNFTK ISIDSTCCQH FGLCGAQYEG DIIFNEPNAG
DDDSTGMSIV GSRIRFQLNA LRNQSMFVNS YYYLHDVVGR WSIDHAATAF PYALVFVYEE
QYTYIQGVAL QSVLLALAVV FGALFVLMDG SLRLTTVVTL CVLSMTFSQL GFLFVWNMIA
GPGAETSINA VSVVNLLACV GLGVEFCVHT AHQFAFSRRH HLGTTANDHT RYALSSVGAS
IFSGITLTKF CGIGVLAFAP SMLFRVYFFR MYLGIVVLGC FHGLVLLPVL LSLIGQPQKY
PNDLSSFLLS EERDDELEDE VRAFK
//
