ID G4YMX9_PHYSP Unreviewed; 695 AA.
AC G4YMX9;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=Multidrug/Oligosaccharidyl-lipid/Polysaccharide (MOP) Flippase Superfamily {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHYSODRAFT_309848 {ECO:0000313|EMBL:EGZ29512.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ29512.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ29512.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ29512.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
CC -!- SIMILARITY: Belongs to the multi antimicrobial extrusion (MATE) (TC
CC 2.A.66.1) family. {ECO:0000256|ARBA:ARBA00010199}.
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DR EMBL; JH159151; EGZ29512.1; -; Genomic_DNA.
DR RefSeq; XP_009516787.1; XM_009518492.1.
DR AlphaFoldDB; G4YMX9; -.
DR STRING; 1094619.G4YMX9; -.
DR EnsemblProtists; EGZ29512; EGZ29512; PHYSODRAFT_309848.
DR GeneID; 20643199; -.
DR KEGG; psoj:PHYSODRAFT_309848; -.
DR InParanoid; G4YMX9; -.
DR OMA; PTTIVGM; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR002528; MATE_fam.
DR NCBIfam; TIGR00797; matE; 1.
DR PANTHER; PTHR11206:SF496; -; 1.
DR PANTHER; PTHR11206; MULTIDRUG RESISTANCE PROTEIN; 1.
DR Pfam; PF01554; MatE; 2.
DR Pfam; PF13917; zf-CCHC_3; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 68..87
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..122
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 137..158
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 170..193
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 205..228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 285..308
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 329..351
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..390
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..425
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 469..490
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 553..695
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 565..591
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 592..619
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 623..676
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 695 AA; 75758 MW; B55FA210F8316981 CRC64;
METSPLLEKP CYRSKQPPAW HDFVDLSSMA AQVSMATLAR AVLLAIDSIF LGHLGVKELA
AASLAQLWTS PVLYAVWASA SALNTLCGQS WGAGNRELTG IWLQFGLMIT TLLSVPVTIW
YWCVGYVLEY STDDQEVVAL ATTFSRVLSG SILPSLLYCC LRQYLQAIGI LLPTTIVGMV
SIFVAAGSNY VLIYGIGPWD GLGFIGSPIA TVVASWFQPF ALFSYAILYR KHHHRAWYGW
NIHALTLSRL RSFLRVAGPI SSNSFVSNLA NALVALVAAR LGARVIAANA VISGLWSLLW
ALFWGYGCAT QVRVANYLGA GKPDLARRIT GLGFICTMVV VVLIATATSV MDQHIITLYT
TDTELLTMCR LVLPVFVVAC VFEAVEILGA GALTGMSQVQ TVFWTSAIAT WLINLPVAYV
GGITLGYGFP ALWVGVLSME LFKVGSYSLA LAQVRWRDMA ERVKEAAEAA PEMEQSTAQA
MGDAGGDAPL GKWAQRKEAR RNMYATSTEK VRVHRRGVGA SSASSAAAMC QKCLRPGHWT
YECKNEAVYV QRPSRSQQLK NPKLRQPFNK DKPPELQDQE RAAAEKSKKL KRKDKDKAKK
KKASSRSHSR SRSRRKRRRS VSSSSSDSSS SDSSSSDSDS SDLDSSGSSS DSSSSSSDSD
SSGSDSDGSS SSSSSDRSSR RRQRSKRRRR DYFGF
//
