ID G4Z0I9_PHYSP Unreviewed; 484 AA.
AC G4Z0I9;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=THUMP domain-containing protein {ECO:0000259|PROSITE:PS51165};
GN ORFNames=PHYSODRAFT_326804 {ECO:0000313|EMBL:EGZ25838.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ25838.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ25838.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ25838.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; JH159152; EGZ25838.1; -; Genomic_DNA.
DR RefSeq; XP_009521126.1; XM_009522831.1.
DR AlphaFoldDB; G4Z0I9; -.
DR STRING; 1094619.G4Z0I9; -.
DR EnsemblProtists; EGZ25838; EGZ25838; PHYSODRAFT_326804.
DR GeneID; 20645502; -.
DR KEGG; psoj:PHYSODRAFT_326804; -.
DR InParanoid; G4Z0I9; -.
DR OMA; CIAYCLA; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR GO; GO:0008033; P:tRNA processing; IEA:UniProtKB-KW.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR14911; THUMP DOMAIN-CONTAINING; 1.
DR PANTHER; PTHR14911:SF13; TRNA (GUANINE(6)-N2)-METHYLTRANSFERASE THUMP3; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF143437; THUMP domain-like; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022603}.
FT DOMAIN 67..188
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 484 AA; 53396 MW; E1CC6C5CB6CF55D3 CRC64;
MSEEVSTYLL LVLRGLEFLV EEEIRSNLQV ESLEICSVQE NPRPPYMQVM QGQAAVGRII
LRTKSSAAEV QELRSVQATL ALLAKSDEID TESDAGVKQI GQLLVEADWD SAVKLWKQHA
VRPVEDDKIT FRGSCVRDGK HAYNSQVVAG EVGARVIEKF GWGVNLTEFD VEVVVVIFYK
FMVAGIALAD PRKIQFRNRL ANESRSALAD SQYVSTLRPS TAYLMLQLAQ HKYGDVVLDS
MCGIGTLPIC SADFTNDGVY ALGGELDELP SGKAGQNAVT RPRPVDIARW DSTRLPLRSH
SIDRIMIDMP FGVRCGNQRQ NNKMYPKVFK ELLRVLRPDG RAVLLVMSKK LFKGAVKDLP
FRVVAEHMVS IGGLAGGIYV IEPTASVPPQ PTPTTTIGQK RSASSLIIVE MRKYSRVDKL
HLYLAKVGQG WLNEDDVDDV STSKLSGGDY FGDDFVTEEG VLHVLVVAPR LDSSAEVPLD
DGIF
//
