ID G4Z152_PHYSP Unreviewed; 1390 AA.
AC G4Z152;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 57.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=PHYSODRAFT_481054 {ECO:0000313|EMBL:EGZ24053.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ24053.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ24053.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ24053.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
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DR EMBL; JH159152; EGZ24053.1; -; Genomic_DNA.
DR RefSeq; XP_009519341.1; XM_009521046.1.
DR STRING; 1094619.G4Z152; -.
DR EnsemblProtists; EGZ24053; EGZ24053; PHYSODRAFT_481054.
DR GeneID; 20655326; -.
DR KEGG; psoj:PHYSODRAFT_481054; -.
DR InParanoid; G4Z152; -.
DR OMA; SWFANMS; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd17917; DEXHc_RHA-like; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF145; ATP-DEPENDENT RNA HELICASE DHX29; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640}.
FT DOMAIN 523..708
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 815..1004
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 113..136
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 189..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 741..785
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 116..134
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 200..218
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 746..785
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1390 AA; 153473 MW; 63BE46B9C208F7FE CRC64;
MAERGFEFRR NLEQLVHDGV LAPRRAAQRS RFRSGVPVSS AEPADVQLQQ RTKKKLARAL
SALREDYGAS LELSREALGY ANTLEDALRF LALQCTSDEL PPTLRAQPTE LLGAKDADGD
SGELLAEEPS RGDAKQTEAL SWTQQYVLSM AAREEEQARR EAEVTPEARE LEELEKRYHE
LVAALNRLKE RKSKKKAKSG DKQKTRELNE QMQDTRQDDE GGLFGLLEEA EATVVSADEI
KKSAAVDTAA IIAAQAAADL AASKGKKGKG GKKKKGRNML KVQAAAAQAA QAQATAAAPW
TGKSPRDHLE QHCRKNGLQK PQYKKLPRPA GGGHLYSVVL ANKTRGKQDV TVRDASDAAR
GFDSISDAKD AVATSALFEL ASDLPLYRVL PPVYRDMWQR WIAERQQTEA AAAAADRDEQ
DELLNEIFNT LPAEIAEKRA DAGNVLEDWS VDDWDADLSD DDEAKAEEAN AVEEESESAR
AAALELSRQL REQLQKQMRS SAYKSKLSQR ESLPIASFKK QVVEMLSDHD VILISGETGC
GKSTQVPQFL LEDLLLSESG GARGQIVCTQ PRRLAAISLA ERVSEELGES NMGTGDSLTG
FQIRLETRMT RRTRLLFCTT GILLRKLQDP HTLGEEVSHV IVDEVHERDL QSDVLLAMLR
QFLAEGNAAR RRKFGGTLPP LKVILMSATL NAASFQQYFG GAAVCPMIEV PGRTFPVEQF
YLEDVLEKTN FVVDEESPAY VPVDESGSDR NSTQVTISGR GGTSYSQQVS WTSSSGKSSS
KATVTETQRM LKETYSESTL QTLERMDPSV VNYELIQALL EHITTETDML SLSKKSDQRR
SASVLVFLPG LQEITTLLDI LAGSRLLRHD PQGREFELLP LHSSLSAQEQ QRIFRQRPGV
IRIIAATNIA ETSLTIDDVK VVIDSGRVKQ MSHDAQRRTN VLEEIWVARA NAKQRAGRAG
RTSGGSCFRL FPQSVFRSVM LEQPVPEIRR APLTSLCLQI KTFGVGGNEE KDGCGEFLRA
CLDPPDDVSI RDALEELFEI GALKREDESL TKLGAHLARL PVDVKVGKLL LLGALFGVFD
AASTCAAVLE TKSPFVAPFG RQSEMKQARQ TFAIGASDLL TDVNAFEAWR YVVQHGKENG
INEKNFCHQN FLSHRGLREL SKLKRQFRGL VTQLGFLPPT ASEVDERMTV QQLATISAVL
YAGLAPNLVH AEPPSGNGPK RAVLRERDHS IVVVHPGSIN YKVASFRASN FLTYAVKLHT
SQVYLPSSSL VLPLAVCLFS HALEPLPQLR RKDKDGNEAI GLRVNDWVVF QSSYRSAALL
QEMRDAVLEV IDSSLQTPPF ARGGNAESKT QQTERESLVD VLRTLFLAEY EERDPHKQLS
GQLCAGKKKH
//
