ID G4Z323_PHYSP Unreviewed; 890 AA.
AC G4Z323;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=DEAD/DEAH box RNA helicase {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHYSODRAFT_312887 {ECO:0000313|EMBL:EGZ20052.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ20052.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ20052.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ20052.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC FANCM sub-subfamily. {ECO:0000256|ARBA:ARBA00009889}.
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DR EMBL; JH159153; EGZ20052.1; -; Genomic_DNA.
DR RefSeq; XP_009522769.1; XM_009524474.1.
DR AlphaFoldDB; G4Z323; -.
DR STRING; 1094619.G4Z323; -.
DR EnsemblProtists; EGZ20052; EGZ20052; PHYSODRAFT_312887.
DR GeneID; 20643538; -.
DR KEGG; psoj:PHYSODRAFT_312887; -.
DR InParanoid; G4Z323; -.
DR OMA; CHGIIQF; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0043138; F:3'-5' DNA helicase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR CDD; cd18033; DEXDc_FANCM; 1.
DR CDD; cd12091; FANCM_ID; 1.
DR CDD; cd18801; SF2_C_FANCM_Hef; 1.
DR Gene3D; 1.20.1320.20; hef helicase domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 1.
DR InterPro; IPR039686; FANCM/Mph1-like_ID.
DR InterPro; IPR044749; FANCM_DEXDc.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR001876; Znf_RanBP2.
DR InterPro; IPR036443; Znf_RanBP2_sf.
DR PANTHER; PTHR14025; FANCONI ANEMIA GROUP M FANCM FAMILY MEMBER; 1.
DR PANTHER; PTHR14025:SF20; FANCONI ANEMIA GROUP M PROTEIN; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF04851; ResIII; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00547; ZnF_RBZ; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF90209; Ran binding protein zinc finger-like; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS01358; ZF_RANBP2_1; 1.
DR PROSITE; PS50199; ZF_RANBP2_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00322};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00322}.
FT DOMAIN 42..71
FT /note="RanBP2-type"
FT /evidence="ECO:0000259|PROSITE:PS50199"
FT DOMAIN 241..409
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 577..745
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 20..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 104..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 861..890
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 107..129
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 136..188
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 890 AA; 98034 MW; 84E5311DA0353245 CRC64;
MEEDEWDDAL LSEIAALETR HLQSHSHQSG PSAAAAAPAP ATAAPWSCRS CTLRNEASSA
ACQVCGTPRG QTYQALTSPP RSSSVTGAAA GRKTVQARLS FDGTSAPVVV PPSQQRQQQQ
QQQQQQEPHE QDVTRIEPSP FSSREQQPVR SSQQTTLTPA AAGSGLVLTS RRSGQSTTAA
TRAASQSPVQ LPRHAAGEDA QAKTRYLDVV ARSNFPQIDY EAAQHFVYPT NYSIRDYQLT
IAEKALYHNT LVSLPTGLGK TLVAAVVMYN FYRWFPTGKI VFMAPTKPLV AQQIKACHEI
MGIPLPDTAE LQGNVPPTMR RVLWNSRRVF FCTPQSLQND LRQGVCAAEK FVCIVVDEAH
RATGNYAYCC VVQMIEAKTP FFRILALSAT PGAKFDVIQD VVANLRISHI ESRSADDPDV
KKYTHARQEE VIVCRLGAQI VEVKTMFLKC FTPIIQRLLR GNIIPFADPE KLSSWHVLQA
RERFRKSPSY ASSRSAESDL ALLVSLLHAK SLLTGHGLSS FRDQILNWAE ERKKGKMSWS
KREMLQSSEF QSLELSLGVT EGATSSANTA SHPKLVKLRE VLLEHFQRHS AAGSSTRAIV
FTQYRVSVSE IVALLRPLSP LLNVQPFIGQ GSSGKSKENK GQTQKVQQEI VRRFRLGEFN
VLVATCIAEE GLDIGEVDLI VSFDALTSPV RMIQRMGRTG RKRVGRVIIL VTEGDEQKKL
ARSASAAKTV SRALTTYKNK FKYSKCPRMI PTGICPALKE LEMNIPTFHA SQVGGKTATP
QVDPDLWQLS DAERAVALMK YFPPNFASSS RNKLFPVVAN RKHLLRRQPR CLGRKGVSSR
VGYSARSLIL QSVVRKINGV EEVMDSDSDD DDKSDDAGNK AGGKQALTQV
//
