ID G4Z6R4_PHYSP Unreviewed; 1395 AA.
AC G4Z6R4;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE RecName: Full=Anoctamin transmembrane domain-containing protein {ECO:0000259|Pfam:PF04547};
GN ORFNames=PHYSODRAFT_492835 {ECO:0000313|EMBL:EGZ20330.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ20330.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ20330.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ20330.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH159153; EGZ20330.1; -; Genomic_DNA.
DR RefSeq; XP_009523047.1; XM_009524752.1.
DR EnsemblProtists; EGZ20330; EGZ20330; PHYSODRAFT_492835.
DR GeneID; 20656879; -.
DR KEGG; psoj:PHYSODRAFT_492835; -.
DR InParanoid; G4Z6R4; -.
DR OMA; WENHRTV; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR InterPro; IPR007632; Anoctamin.
DR InterPro; IPR049452; Anoctamin_TM.
DR PANTHER; PTHR12308; ANOCTAMIN; 1.
DR PANTHER; PTHR12308:SF73; INCREASED SODIUM TOLERANCE PROTEIN 2; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF04547; Anoctamin; 1.
DR SMART; SM00248; ANK; 6.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 724..752
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 758..778
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 833..854
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 874..895
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 916..939
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1049..1072
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1103..1124
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1136..1157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 717..1168
FT /note="Anoctamin transmembrane"
FT /evidence="ECO:0000259|Pfam:PF04547"
FT REGION 1174..1198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1395 AA; 157316 MW; 412FCC4C1782667D CRC64;
MDLYEACENG NEERVVELLV VGHDAGLTPS PELQLQVRGI AGRTALLAAC MGGQTSVVRL
LLGEKCAVHF TSRMVMKDSG SDAVPMVEVQ LPPNWAIPPS ELLEGRQHVD DFGNTPLQCV
SCFGCGSSVK HVDDGLEITR QLLLHGDQPN LPKKSNKWTP LHWGAYNGNH EQIAMLLDPV
VHVGDGTQRF AKTQHGIPLL MDTDDLFPVD IAGRRGLALR DERVALQRQL SSGEDDVNDE
YAHWRLRLDH VEAVRLFIHD FVANGAHLTR YVGEMNARNP QHLQQNKRSK ANAVTIQDAV
RYGQHLLYWA GCFGLVDEVR SLLRLELKMS SVGGGASTAG KAAVKPSVAQ GGDNQAIKIS
LRILYTCSCE AGKRQSVLHA VAGHGQLEML KLLLDQMLFD QQCPSDAATF VGSSMTSSLL
KGGKPKKNIV VPTAKEAEVS KPNELERAES DKHDHLEIAE LVNAGWRNYR NETPLFHAVI
YLQERAVRMF AGILSPKSLA WELQNVNVEG SSLHHVASED TRRVLGIEHQ AARPEYVLLF
DGIKKKQFKE TVIETMHEES FIAPSLVVSR AGMKDLAAGM CWAQGQTDYL VVGATDDVLV
QQAQVLQLKV KHRGSSSRSK YDASSPELYE SFRSLQRQQV IRSIIQRKIN LQKHLKNGNI
KSIFPLHDAM GCRNIIRHWG YTDSYQRIFQ PFTGNSVEQF LFERKKHQYE MLWPLLTYFG
EKHAFYYAFV TFYTVWLLPM ALVGVTCQLL WLVDDVSFVP PLFAIVVSIW ATLMVERWKR
KRSEIQRKFG HFRRNRSEET PGFYGDFQVE TTLVRVKTAV DVNFPRALQL ARVYTGLPLL
MTMGIAAVAI FVAVKTNTAS SAIVHNAMPW LPTLLVPYVV PLMNAISMLL LDNWYTRLAR
ALTTWENHRT VWEFESMLAV KLFWFKFLNA FISLFWIAFV DQNAAALRKQ LLIIMGVRQL
WNSMKRDMLP MLHVRYKWKS AGFRFRSTTS IPRANHCWSL SSHEWYDVEL SHPIAASSRE
GERQPPPPIV LVQELMYPHD FLMGKQMEVV LQFGYITMFV SVLPVAPLFA LLSNVVAMRL
DVLSCTQAKQ RPPFESETEV STFMSILEFM SFAAVAVNCA VLFFTTRSDF ESLMQLWILL
VIEHVVLGAK ALLSLVIDDS ASWVRLDEDQ SDEEEKKRML GAATESNPPT ARSATASNEE
AQAVVHRGSA DLNSSKLNQV LAKQYLAALQ ERDEALQREQ TTRQLLAESM KRVQVDVDAS
NGGMPHRRHC FVCYALGDVV KTWEKRCLSC HIALCLSCDE ILHLDDLGVK EPAHFRIKVP
KHLKELRRHV ESFIAKQHSL PDAELHLTAD KAFKRCCINI RIALRYLRNH ERQSSYLGGL
NPAVSPALTP VSKEL
//
