ID G4ZEG9_PHYSP Unreviewed; 1275 AA.
AC G4ZEG9;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE RecName: Full=Cyclic nucleotide-binding domain-containing protein {ECO:0000259|PROSITE:PS50042};
GN ORFNames=PHYSODRAFT_332228 {ECO:0000313|EMBL:EGZ18434.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ18434.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ18434.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ18434.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH159154; EGZ18434.1; -; Genomic_DNA.
DR RefSeq; XP_009527492.1; XM_009529197.1.
DR AlphaFoldDB; G4ZEG9; -.
DR EnsemblProtists; EGZ18434; EGZ18434; PHYSODRAFT_332228.
DR GeneID; 20646411; -.
DR KEGG; psoj:PHYSODRAFT_332228; -.
DR InParanoid; G4ZEG9; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005216; F:monoatomic ion channel activity; IEA:InterPro.
DR CDD; cd00038; CAP_ED; 2.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 1.10.287.630; Helix hairpin bin; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 2.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR PANTHER; PTHR45638; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR PANTHER; PTHR45638:SF11; CYCLIC NUCLEOTIDE-GATED CATION CHANNEL SUBUNIT A; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 2.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 2.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 191..211
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 223..245
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 313..332
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 660..678
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 690..712
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 739..762
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 401..546
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT DOMAIN 970..1058
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
FT REGION 1124..1159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1275 AA; 144452 MW; 3C208C8956E27F43 CRC64;
MGGPPSKIHR GGYVGTATLT QQERGEGYME HVSANSGCIL LFVSRDQLRA MEAIFPPLKT
ELLTVDRRLM SSELASMHVQ TDREEYNQVR SMLHRVQLAL ASVFTIVYDP DSLFTLAWET
WLFMVMTTQW VVVMFQAFFP LEERHNKVDS LMVFLECSFL LDVFIRSRLG FYEYGNKVMD
IHRIKHQYFR SGAFALDIIA LLPLYAVNWG IESYQRWDLL NLHLFKLLCY TFMLSHILGC
IWFNFASGVA TPKFSDSSAP TATQTAFGEN LWLPSKKLEN GSLMLQYMAS LYWSFGLMSS
SGESEYPQTT AQCIFSVVTM TAGVFLFAYV LGNFTDIIEL TSSESREFDV KMGAARQMLD
HFKIPTILQE RQHLLGECSP PSLLTDIRLV YLKPMIEKVD FLAGMEIPIT RMLVSQFTQV
LVFRGELVFR FGDCGSDMFF VFTGILDVLL PMQLAKRSRP TFRAVADTVA SKENASFQAG
PTPEDIDDSL QQISIPGQLK KMNEISAGRY FGENGLFTIG ERDAYIQART SCILYRLSRE
SLELVFERYP KWKEKVIQIA NIHREQARLE QLSRDEQRRG MLICGGRALS RSDIVNERAE
GSKGARYHTR LQRSSTGSSS RILPVPTSVG LVDQQVQKPL LRLVDGFLHG VPVQSKFPHF
WLRFIICCTM FVAVMTPYQL TMDAMDRTAV VPVLVIIIGI LCEVAIVVDL WFSWHVRESQ
ASMELYDQKL RSVYRKERML WDILAAIPFY DVLAVLGCRA WFKLLRCIKI FNLGSYFNEL
NRLSMDAGFG AEWEGWLPSQ DLVVSDPQNP SSSQLALRLL RGLFFAMVTF VKKAYCPEPE
TATLYAFHIG MSFVGLITMS YVIGELASLF ISYIGLEVGF RKNYIAVDLY MARLRLSDRL
KTRTYAFMTS LWSSHAGVNY EELLAEMPKA IRTSYVLQVS TKLLSWFIMK VIAPVCWDES
QRMDEFTRAL AERLRFECYP RDESVVTEGS IVRAMYFVIK GHLSMHSRSL LDRPVGLRSG
SYFGERGLLG CTISAYTVRT VRACDLLSLS SEAFVQVLQG HLFTRLALNL CERAYKHLKK
QHIASCSRTD MEEHWGAALL GAVQAIQTQR QPAAQANLPV AKEVAGKEAG DPPPNSDRIP
LSSLRRKVTH QNSKAPEKQD HLLRSGHKDV PNVGEAKGVH IADKESDELP ANIDLMFKAL
KTPHSCFEAF APLLHIMLAT DPLEWHVSFN TLNSTALPNA IESVDNSGCR RRNSPPAAEH
TIASPLISRN EEIEQ
//
