ID G4ZF75_PHYSP Unreviewed; 1412 AA.
AC G4ZF75;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 51.
DE SubName: Full=Pleiotropic drug resistance protein ABC superfamily {ECO:0000313|EMBL:EGZ16578.1};
GN ORFNames=PHYSODRAFT_500678 {ECO:0000313|EMBL:EGZ16578.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ16578.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ16578.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ16578.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. ABCG family.
CC PDR (TC 3.A.1.205) subfamily. {ECO:0000256|ARBA:ARBA00006012}.
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DR EMBL; JH159154; EGZ16578.1; -; Genomic_DNA.
DR RefSeq; XP_009525636.1; XM_009527341.1.
DR EnsemblProtists; EGZ16578; EGZ16578; PHYSODRAFT_500678.
DR GeneID; 20657872; -.
DR KEGG; psoj:PHYSODRAFT_500678; -.
DR InParanoid; G4ZF75; -.
DR OMA; QAIFCTI; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03232; ABCG_PDR_domain2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR043926; ABCG_dom.
DR InterPro; IPR034003; ABCG_PDR_2.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010929; PDR_CDR_ABC.
DR PANTHER; PTHR19241; ATP-BINDING CASSETTE TRANSPORTER; 1.
DR PANTHER; PTHR19241:SF625; ATP-DEPENDENT PERMEASE PDR10-RELATED; 1.
DR Pfam; PF01061; ABC2_membrane; 2.
DR Pfam; PF19055; ABC2_membrane_7; 1.
DR Pfam; PF00005; ABC_tran; 2.
DR Pfam; PF06422; PDR_CDR; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 465..486
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 498..519
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 539..566
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 572..597
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 609..626
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 694..717
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1130..1150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1162..1180
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1201..1228
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1240..1262
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1269..1288
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1300..1319
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1385..1407
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 97..363
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 780..1025
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 730..761
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 730..749
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1412 AA; 156834 MW; FD6CFA8242F1408A CRC64;
MVAEPRTPEP PVGYNTGQEM MARGPYALHE DISAKVETAL GRAMAQMEVH FKHVSLAADL
VAVHDPRHRR RLDANDQEIA DPRNELPTLP NHVMKKVAAV SAKKHSVRKH ILHDVTGSFR
PGTVTLILGQ SGAGKSALMK LLSGRFPMKK EISVEGEMTY SGVPREKLLK RLPQLVNYVT
QNDTHMPTMT VRETFEFAHE CCGPHLDKRT SELLSRGLPA ENASALQAAS SVFKHYPEIV
LQTLGLEDCQ HMIVGNALHR GISGGEKKRM TTGEMEFGMK YVTLMDEITT GLDSAAAFDI
IAAQRSMAQR FHKTVVISLL QPSPEVFELF DSVLLLNEGR VLYHGPTSQV QHYFESLGFI
CPPRRDIADF LCDLATPQQI QYQQGRPPQE HPTHPMLASE FADLWVNSSL YQVLESEDDA
RAAALKDSVD AANFMKPVRE FHQSFWPSTW TLMKRQFILT KRNHAFLIGR AMLVIIMGLI
FASLFYQMDM ADTQVTMGVI FAAMLFLGLG QAAMLSTFYD SRNVFYKQRA ANFYRTSSFV
LASSISQIPL ALLESLMFGS LVYWVGGFVN EAGAYLLFEL FLMLVILVFL ALFFFLVAAT
PNLSIAKPVA MVNLMIFILF GGYVVAKNSL PDWLIWLYGI DPVAWTVRSA VVSQYRSSEL
DVCVYESVDY CAAYNMTMGQ YALSLFDVPS EKSWVGYGIL FMAGAYVFFM MMSYFALEYH
RYERPEHIAL PHEEKETAST DDEEGYGLMK SPRTDTPSSG DVVLRVNSSH PERNVDPVSV
AFKDLWYTVQ APAGPGQPVQ SLDLLKGITG YAPPGKITAL MGSTGAGKTT LIDVIAGRKT
EGTIKGKILL NGFEASDLSV RRCTGYCEQN DIHSTGSTFR EAITFSAFLR QGSDVPDSRK
FDTVDECLEL LGLEEIADQM IRGSSMEKMK RLTIGVEMAA QPSILFLDEP TSGLDARSAK
VIMDGVRKVA DSGRTVLCTI HQPSTDVFHL FDSLLLLKRG GETVYFGDLG HECSALINYF
EAIPSVQRIT DGYNPATWML EVIGAGVASQ RQVGQANEDQ QPIDFVKYFH ASANKKSLDG
KMTEAGLFQS SDHLKPVSYS KKRAASSATQ LRFLLDRFFT MYWHTPSYNL TRLCISIFLG
LVFGLVYISA EFKTYQGINS GLGMVFISTV FIGVSFISIL PMAFEERAAF YRERASQTYS
ALWYFVSFTI VELPYVFVGA ALFTVIYYPM VGLEGFVNGV VYWINVALMI LFQAYMGQLL
VFALPSIEVA AVIGILFNAI CLLVMGFNPP AMQIPQGYKW LYAIAPLRYS FSALAAIAFG
KCSNKQLVNI MVASASPGGI APLDMSDYPH GCQIVQNAPA TVGEIPVQTY VEAVFGIKNA
HVAQYFGIMV GMIVFFRVLT ALAMRYINHQ QR
//
