ID G4ZFR4_PHYSP Unreviewed; 517 AA.
AC G4ZFR4;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 49.
DE RecName: Full=Tyrosinase copper-binding domain-containing protein {ECO:0000259|PROSITE:PS00497, ECO:0000259|PROSITE:PS00498};
GN ORFNames=PHYSODRAFT_332303 {ECO:0000313|EMBL:EGZ18532.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ18532.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ18532.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ18532.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
CC -!- COFACTOR:
CC Name=Cu(2+); Xref=ChEBI:CHEBI:29036;
CC Evidence={ECO:0000256|ARBA:ARBA00001973};
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DR EMBL; JH159154; EGZ18532.1; -; Genomic_DNA.
DR RefSeq; XP_009527590.1; XM_009529295.1.
DR AlphaFoldDB; G4ZFR4; -.
DR STRING; 1094619.G4ZFR4; -.
DR EnsemblProtists; EGZ18532; EGZ18532; PHYSODRAFT_332303.
DR GeneID; 20646434; -.
DR KEGG; psoj:PHYSODRAFT_332303; -.
DR InParanoid; G4ZFR4; -.
DR OMA; YSHHTLI; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR Gene3D; 1.10.1280.10; Di-copper center containing domain from catechol oxidase; 1.
DR InterPro; IPR008922; Di-copper_centre_dom_sf.
DR InterPro; IPR002227; Tyrosinase_Cu-bd.
DR PANTHER; PTHR11474:SF124; TYROSINASE; 1.
DR PANTHER; PTHR11474; TYROSINASE FAMILY MEMBER; 1.
DR Pfam; PF00264; Tyrosinase; 1.
DR PRINTS; PR00092; TYROSINASE.
DR SUPFAM; SSF48056; Di-copper centre-containing domain; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS00497; TYROSINASE_1; 1.
DR PROSITE; PS00498; TYROSINASE_2; 1.
PE 4: Predicted;
KW Copper {ECO:0000256|ARBA:ARBA00023008};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..517
FT /note="Tyrosinase copper-binding domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003472040"
FT DOMAIN 79..96
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00497"
FT DOMAIN 250..261
FT /note="Tyrosinase copper-binding"
FT /evidence="ECO:0000259|PROSITE:PS00498"
SQ SEQUENCE 517 AA; 57378 MW; 6C9DE1E38F13AFAA CRC64;
MPSSRSMVAL WLAAALLCLA NGQQVGTSCP QPRIRKSWDS YTAAEKALYT EAVGVAMDRG
FHQKFVQIHT EQLTGLEAHQ SCVFIYWHRM LLLGYENMLR SLNTAYQCIT LPYWDHLSGS
ARQANNNCSS IEECSSIIAD FGGTTTGVSK SLSVYGSSIP NSIKTVCVTQ GPAYRFCGNN
TGCAHCILRT RSKYLSATTY PNEASFGSVY QQVFTYSDSG SFTSAVERGI HNTIHNALGG
VMTYLQAPVD PVFYSHHSLI DLLQTIYLKC QIGDEKAFLS AENKSSDPRV WTSCTRSNGG
NFRDSDNITM RALANDGKTY VNVWQDPNNI LYPFFKDMPY QYADYVDAKD LKGYSYTYDI
SGGLANMYQN CKDSNTFSAI SLLADSQQTT KKKNPLLPTI SEGTEEDDAV RLWHIALFEA
AQIVGFQDWA ARDQMEMIAC VHHGECIGPI DDYTNLFRTN FGVTGHTRCF SILQDIMEGT
RIIGIPMWRE ITSRFLPCPL QEEDGSDSEG GSEAAVA
//
