ID G4ZWA3_PHYSP Unreviewed; 1950 AA.
AC G4ZWA3;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Lipid exporter ABCA1 family {ECO:0000313|EMBL:EGZ11630.1};
GN ORFNames=PHYSODRAFT_562706 {ECO:0000313|EMBL:EGZ11630.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ11630.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ11630.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ11630.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; JH159157; EGZ11630.1; -; Genomic_DNA.
DR RefSeq; XP_009531963.1; XM_009533668.1.
DR EnsemblProtists; EGZ11630; EGZ11630; PHYSODRAFT_562706.
DR GeneID; 20663674; -.
DR KEGG; psoj:PHYSODRAFT_562706; -.
DR InParanoid; G4ZWA3; -.
DR OMA; FMWNVIA; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR CDD; cd03263; ABC_subfamily_A; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR013525; ABC2_TM.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR026082; ABCA.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR19229:SF36; ATP-BINDING CASSETTE SUB-FAMILY A MEMBER 5 ISOFORM X1; 1.
DR PANTHER; PTHR19229; ATP-BINDING CASSETTE TRANSPORTER SUBFAMILY A ABCA; 1.
DR Pfam; PF12698; ABC2_membrane_3; 2.
DR Pfam; PF00005; ABC_tran; 2.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 414..435
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 456..478
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 490..510
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 522..544
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1031..1049
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1061..1080
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1272..1301
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1337..1356
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1368..1392
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1404..1424
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 1483..1505
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 685..918
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 1546..1779
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1950 AA; 213322 MW; 1DEE186FA2CE66B1 CRC64;
MGDSEKVGGS TRPRPGGPGF LRTQQTLLAK SWLLKKRHWV AMLLEIFLPV LFILLITALK
RLSTDVQVPA GWSSTASDGK SFSLMQNGYL VQEPTMNGLM TYLAVRTASE IHNTTGVSGT
EQEVCAFSVG YGGFVSTDTS SQYAVLPSCR SYFTPYKLAI APDNDFTRKY FFETVKQWYP
RVMLNTSMGV TMPSLEDSVI FFDTEDAMES YIGEVGYGKG FATPIVYAAL VFDQYPEGDK
IGTFQSIEYS VRMNSTQGGG GSPGVVPRTL GDPAFESPFQ RTIEQAYYSS YASRGFMTLQ
TLVARFVNCM PDWDESTKST TGVCKQKLST AVSNTANDDR LFHAVDGDVL LGAALSVPFA
SSGTGWQTLL TASGREQLLV PLRQAPQPYF ATTVAPFPID SFLSAPFYDQ VSSVFPLVFI
LAYLYAISRV LVVLIQEKET RSREYLKILG MSESAIILSW YITYFVIFLI SAILQAIAST
AGLFPNSDPG LIFLFFLLFS LSVLAFGFFM STLFSRSRTG SFAGMVLFFF MYFVSSGFSS
TSSIGSKTGA CILPPVALSF GVQSLATAES TGVGMSFESS STVVDNFKFG SSIGMLFFDI
ILYTLLGLYL ERVIPREYGT VEKWYFPLQP SYWVRSFRAK RCLSKVNDVA NNVVNGSHAV
LDIENPNMEV ASEELRHQER TGEALVISDI KKEFVVPGGI KRAVRGVSLA MYKDQITCLL
GHNGAGKTTL ISMLTGMIAP SAGDASFRGL SLVHDMAEIR QSLGLCFQHD VLYSELTVEE
HLLFYGRVKG YRGAALKEEV ITKITEVGLT EKRHVFAGSL SGGMKRKLSV AICLLGDSSL
VFLDEPTSGM DPYSRRSTWE ILLNNRANRV MVLTTHFMDE ADILGDRIAI MAEGQLRCCG
SSLFLKNRYG AGYNFTLVKS SDPAKPCKET QLHSLVTERV PSAKVLSNVG AEIAFQLPLD
STASFPALFE ELDSKMGDLG VLSYGISVTT LEEVFIKVAE ANDEDNQHTL NKNAASPGAA
DAGLPPGGPT IASLTGMTMF FVHLSALLLK RFRIAKRDRR VIIFSALLPV TLLAAGFIIL
KTSSLTRSDE KLALATDDFE ASVPNVPYFC EADDSKWCSS TLDLFTGGKP SPFTSADIPS
PPYTTWPTTV FGVNYTEADL ASYSNPHSNE YCLRMGDQIY QRGFGKDDDG KVIQPPVKGQ
YGGYLVHGSE SEQMFGYHLF VNTTAAHGAV IFKALMDQAL YRFMAGSGSG ATDVTLKANT
YPLPMTAATQ ALFGSFLAFT ACIFIVIAFA FFPASIVGFL VKEKQAEHNS KHQQLVSGVS
LPAFWLANYL WDLLTYVIPF IAAIVLIQIF DIAAFTGNDC VSCTSQTFPA IVLLFILFGL
AICPFTYCLS YFFKEHASAQ TYTIMANFLL GVVLMVVSFI LDVVSTSSAD ANKVLKFFWR
LSPLFNLGSA LLNQCLSEIT AAFGRTSGTV SPFDMDVMGW ELLYLALDAI IFFTVAVGID
FLLSFPKIKA AIFKDPHLED APYEEDEDVA REAERVRSGG ADGDAVKLLG IRKVYNGNKV
AVRNLSFGLP KGECFGYLGI NGAGKTTTMK MMTGDILPTT GSGTLGGFDI LGEQLEVRRL
IGYCPQFDAL FELMSVREHL ELFARIKGVS SANLNDVVKI LMHQMNLDDF ENKLAGTLSG
GNKRKLSVAI ALIGSPPIVF LDEPSTGMDP VSRRFMWNVI AAISTQRKES TIILTTHSME
ECEALCTRVG IMVGGRLRCL GSVQHLKHRF GDGLMLELKL MGTPTHDIDA RVASVFGGSA
STTTFPRAEL RAKCEALGDA SWADKIVMSH ATGYALATAL ERDGTMRLGM LCAWWAAEER
FLGLDAFLRE SFAVDANTGV KMLERQNDMC RYKLTGQVPR LASVFRRVEA SKQQLGIREY
AVSQTTLEQI FNNFAGQQSE EKGVARGIGG
//
