ID G5A3P3_PHYSP Unreviewed; 376 AA.
AC G5A3P3;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 13-SEP-2023, entry version 47.
DE RecName: Full=Nudix hydrolase domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHYSODRAFT_523677 {ECO:0000313|EMBL:EGZ09416.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ09416.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ09416.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ09416.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
CC -!- SIMILARITY: Belongs to the Nudix hydrolase family.
CC {ECO:0000256|RuleBase:RU003476}.
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DR EMBL; JH159159; EGZ09416.1; -; Genomic_DNA.
DR RefSeq; XP_009534277.1; XM_009535982.1.
DR AlphaFoldDB; G5A3P3; -.
DR EnsemblProtists; EGZ09416; EGZ09416; PHYSODRAFT_523677.
DR GeneID; 20660691; -.
DR KEGG; psoj:PHYSODRAFT_523677; -.
DR InParanoid; G5A3P3; -.
DR OMA; FIFYAEP; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR CDD; cd02883; Nudix_Hydrolase; 1.
DR Gene3D; 3.90.79.10; Nucleoside Triphosphate Pyrophosphohydrolase; 1.
DR InterPro; IPR008598; Di19_Zn-bd.
DR InterPro; IPR020476; Nudix_hydrolase.
DR InterPro; IPR015797; NUDIX_hydrolase-like_dom_sf.
DR InterPro; IPR020084; NUDIX_hydrolase_CS.
DR InterPro; IPR000086; NUDIX_hydrolase_dom.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR21340:SF0; BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE [ASYMMETRICAL]; 1.
DR PANTHER; PTHR21340; DIADENOSINE 5,5-P1,P4-TETRAPHOSPHATE PYROPHOSPHOHYDROLASE MUTT; 1.
DR Pfam; PF00293; NUDIX; 1.
DR Pfam; PF05605; zf-Di19; 1.
DR PRINTS; PR00502; NUDIXFAMILY.
DR SUPFAM; SSF55811; Nudix; 1.
DR PROSITE; PS51462; NUDIX; 1.
DR PROSITE; PS00893; NUDIX_BOX; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003476};
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 154..182
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 225..357
FT /note="Nudix hydrolase"
FT /evidence="ECO:0000259|PROSITE:PS51462"
SQ SEQUENCE 376 AA; 42394 MW; 7FE4B865B85D2C3E CRC64;
MKRALVIRNV SSHDMPLDSL DNACVHACTA QGFITELAVN HEDDIRHQLM QTHARASAHH
DRRVAYQQTP PMYSPVPFDA VLFRASGLSE HHLYPLLRMI RTISKQIFLC VFSPQLAEHP
MGRYQCFQEG ASMVTDSLDA VRDSRGRSGG RDGFTCPFCG KNGMDEDQLW RHCPMYHINE
KNTDNIKCPI CRETPRGPFQ VHMHNAHGPP GRHEMASEFN MADSTLYSFA LVVCHNKKYN
SFLLVQEFAN SGFWLPGGRI DSGENPAQAA IRETKEEAGI DIRLTGLIKL EYHPKQDRNG
SQYVRMRFIF YAEPLDCDQP PKSIPDYESA GATWCRADQV ASLPLRGSEP VTYFNHIASG
GPIYPLELIH MTSSST
//
