ID   G5AEW3_PHYSP            Unreviewed;       345 AA.
AC   G5AEW3;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   27-MAR-2024, entry version 42.
DE   RecName: Full=NAD(P)-binding domain-containing protein {ECO:0000259|Pfam:PF16363};
GN   ORFNames=PHYSODRAFT_356174 {ECO:0000313|EMBL:EGZ05753.1};
OS   Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS   (Phytophthora megasperma f. sp. glycines).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ05753.1, ECO:0000313|Proteomes:UP000002640};
RN   [1] {ECO:0000313|EMBL:EGZ05753.1, ECO:0000313|Proteomes:UP000002640}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P6497 {ECO:0000313|EMBL:EGZ05753.1,
RC   ECO:0000313|Proteomes:UP000002640};
RX   PubMed=16946064; DOI=10.1126/science.1128796;
RA   Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA   Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA   Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA   Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA   Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA   McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA   Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA   Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA   Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA   Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT   "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT   of pathogenesis.";
RL   Science 313:1261-1266(2006).
CC   -!- SIMILARITY: Belongs to the NAD(P)-dependent epimerase/dehydratase
CC       family. {ECO:0000256|ARBA:ARBA00007637}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; JH159165; EGZ05753.1; -; Genomic_DNA.
DR   RefSeq; XP_009538614.1; XM_009540319.1.
DR   AlphaFoldDB; G5AEW3; -.
DR   STRING; 1094619.G5AEW3; -.
DR   EnsemblProtists; EGZ05753; EGZ05753; PHYSODRAFT_356174.
DR   GeneID; 20649959; -.
DR   KEGG; psoj:PHYSODRAFT_356174; -.
DR   InParanoid; G5AEW3; -.
DR   OMA; PIKLFNH; -.
DR   Proteomes; UP000002640; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR016040; NAD(P)-bd_dom.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR43574; EPIMERASE-RELATED; 1.
DR   PANTHER; PTHR43574:SF90; NAD(P)-BD_DOM DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF16363; GDP_Man_Dehyd; 1.
DR   PRINTS; PR01713; NUCEPIMERASE.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000002640}.
FT   DOMAIN          27..332
FT                   /note="NAD(P)-binding"
FT                   /evidence="ECO:0000259|Pfam:PF16363"
SQ   SEQUENCE   345 AA;  38150 MW;  0D80ECD0652DFD35 CRC64;
     MAPNPYEVSD ALADVTSVNP GVRRRILVTG AAGFIGFHTA KALLARGDDV VIVDEMNDYY
     DVKLKQSNLD WLTKNYGERV TVVIGDLCDA QLVRRVLKET SPAAMVHLAA RAGVRPSIDN
     PLLYIHANVV ATMVLLDACR EFGIKKFVYA SSSSVYGGSL KESFSEEDIV DFPVSPYAAT
     KKSCELLAHT YHHLYGMDTI GLRFFTVYGP RGRPDMAPFK FMDRIARDVA IDQYGDGSSS
     RDYTFIDDIV QGVLLSLDRG FGCEVFNLGR GTPVLLTDFI QIIEGLVGKK AKINILPDQP
     GDVPRTSADI SKAERLLGYK PTTPLEQGLK KTWEWYSEFY NNASP
//