ID G5AF61_PHYSP Unreviewed; 647 AA.
AC G5AF61;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 47.
DE RecName: Full=CRAL-TRIO domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHYSODRAFT_532658 {ECO:0000313|EMBL:EGZ05851.1};
OS Phytophthora sojae (strain P6497) (Soybean stem and root rot agent)
OS (Phytophthora megasperma f. sp. glycines).
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1094619 {ECO:0000313|EMBL:EGZ05851.1, ECO:0000313|Proteomes:UP000002640};
RN [1] {ECO:0000313|EMBL:EGZ05851.1, ECO:0000313|Proteomes:UP000002640}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P6497 {ECO:0000313|EMBL:EGZ05851.1,
RC ECO:0000313|Proteomes:UP000002640};
RX PubMed=16946064; DOI=10.1126/science.1128796;
RA Tyler B.M., Tripathy S., Zhang X., Dehal P., Jiang R.H., Aerts A.,
RA Arredondo F.D., Baxter L., Bensasson D., Beynon J.L., Chapman J.,
RA Damasceno C.M., Dorrance A.E., Dou D., Dickerman A.W., Dubchak I.L.,
RA Garbelotto M., Gijzen M., Gordon S.G., Govers F., Grunwald N.J., Huang W.,
RA Ivors K.L., Jones R.W., Kamoun S., Krampis K., Lamour K.H., Lee M.K.,
RA McDonald W.H., Medina M., Meijer H.J., Nordberg E.K., Maclean D.J.,
RA Ospina-Giraldo M.D., Morris P.F., Phuntumart V., Putnam N.H., Rash S.,
RA Rose J.K., Sakihama Y., Salamov A.A., Savidor A., Scheuring C.F.,
RA Smith B.M., Sobral B.W., Terry A., Torto-Alalibo T.A., Win J., Xu Z.,
RA Zhang H., Grigoriev I.V., Rokhsar D.S., Boore J.L.;
RT "Phytophthora genome sequences uncover evolutionary origins and mechanisms
RT of pathogenesis.";
RL Science 313:1261-1266(2006).
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DR EMBL; JH159165; EGZ05851.1; -; Genomic_DNA.
DR RefSeq; XP_009538712.1; XM_009540417.1.
DR AlphaFoldDB; G5AF61; -.
DR EnsemblProtists; EGZ05851; EGZ05851; PHYSODRAFT_532658.
DR GeneID; 20661772; -.
DR KEGG; psoj:PHYSODRAFT_532658; -.
DR InParanoid; G5AF61; -.
DR OMA; WNFTIVA; -.
DR Proteomes; UP000002640; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001849; PH_domain.
DR PANTHER; PTHR45657:SF61; CRAL-TRIO DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45657; CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED; 1.
DR Pfam; PF00650; CRAL_TRIO; 1.
DR Pfam; PF00169; PH; 1.
DR SMART; SM00233; PH; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
DR PROSITE; PS50003; PH_DOMAIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000002640};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 67..86
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 92..115
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 208..387
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT DOMAIN 501..602
FT /note="PH"
FT /evidence="ECO:0000259|PROSITE:PS50003"
FT REGION 425..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 607..647
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 425..445
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 647 AA; 71630 MW; 70BCAFFA2FAE0AFC CRC64;
MMLVLHFSDG GRLRIPCQRF LKHEGRAFYR VVLNGKRPMR VLVRATRAVG RKKGDLRGTL
RGTYRQIFKL SCGIVLVYLS AASVFTHVLG SIVVLPAVYV GLTVAVLVFS VEVFFPGQVV
TARQIKPKDE HQLGNWNFTI VALEASDSER LENTSNKAMQ EAAAIKVPPA FVVAENGDVA
KATERYQNTL AWRKEVLADS ILTMPQTHYD TIKANYTQFL HKHDKLGHPL YVEKVGSINI
PQLKKAGVSQ EALFKHYLFA MEFTIKYAAH QICPCDACAS SETQKMCIVL DARGIGMRDM
GGEAFEFIRR CTSVMQRHYP QRSFKIFIVN VPSWFGMAWK GVKPLLNEAT RAKTNILTES
ETAGALLEFI DAESLPVEYG GTCSCAGGCE TSSSYQRLQR ALVQSVLECK PFEADELMQS
IAVERSGKSR SSSEADASSS ATPASSPPPV MGPIKRETSA TAVLDQLFRI GSSSTDDGFT
LDGVDDEGFC RSIPAGFFSE EVLKAGYLLK RSLRHKQFNP IWHRQLFILH PQFLRFAKTL
DSEIYQIVSL THDTVVQKTT KQNNSFEIVT PLMAANGHSL LLYAPTPSVL NTWVDAIQGA
IEQMKLRAPT PAASPERSPI VSPRAKQEAS PEPDDLPTAL NAHETPR
//
