ID G5ALL0_HETGA Unreviewed; 400 AA.
AC G5ALL0;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Trafficking kinesin-binding protein 2 {ECO:0000313|EMBL:EHA97920.1};
GN ORFNames=GW7_12811 {ECO:0000313|EMBL:EHA97920.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHA97920.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHA97920.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000256|ARBA:ARBA00004173}.
CC -!- SIMILARITY: Belongs to the milton family.
CC {ECO:0000256|ARBA:ARBA00007007}.
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DR EMBL; JH165794; EHA97920.1; -; Genomic_DNA.
DR AlphaFoldDB; G5ALL0; -.
DR STRING; 10181.G5ALL0; -.
DR Ensembl; ENSHGLT00100066829; ENSHGLP00100037041; ENSHGLG00100035647.
DR InParanoid; G5ALL0; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
DR InterPro; IPR006933; HAP1_N.
DR InterPro; IPR022154; TRAK1/2_C.
DR PANTHER; PTHR15751; TRAFFICKING KINESIN-BINDING PROTEIN; 1.
DR PANTHER; PTHR15751:SF13; TRAFFICKING KINESIN-BINDING PROTEIN 2; 1.
DR Pfam; PF04849; HAP1_N; 2.
DR Pfam; PF12448; Milton; 1.
DR SMART; SM01424; HAP1_N; 1.
DR SMART; SM01423; Milton; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00023128};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT DOMAIN 1..169
FT /note="HAP1 N-terminal"
FT /evidence="ECO:0000259|SMART:SM01424"
FT DOMAIN 231..380
FT /note="Trafficking kinesin-binding protein C-terminal"
FT /evidence="ECO:0000259|SMART:SM01423"
FT REGION 273..297
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 128..162
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 400 AA; 45017 MW; 941FE9AFF8D23FC2 CRC64;
MILGTDRVEQ MTKTYNDIDM VTHLAERDRD LELAARIGQA LLKRNHVLSD QNKALEEQLG
EGTTACDCIK ELHETNAQMS RMTEELSGKS DELIRYQEEI SSLLSQIIDL QPRLKEHVIE
KEELRLQLQA SKDGQRQLTM ELRELQDKNM ECLGMLHESQ EEIKELRSRS GPAAHLYFSP
SCGPFTGESL AAEIEGTMHK KLILDEESSL FKQNPQQKWV FDTVKVANDT RGLSVPLPAL
LPIPRSNRSS VIMTTKPFES GVQQTEDRAL LGQGSDSKEV PGGSQPRSHP GPSGDSDLDI
ALHHLSLHWQ NYFSEKQFFA EEWKWKIQVL ADQKEGVSGC DTPTECLASL CTDQLEISSA
SCLRGFMPEK LQIVKALEGS QTLHHWQQLA QPNFGTILDT
//
