ID G5AMK4_HETGA Unreviewed; 333 AA.
AC G5AMK4;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=GTPase IMAP family member 5 {ECO:0000313|EMBL:EHA98264.1};
GN ORFNames=GW7_03461 {ECO:0000313|EMBL:EHA98264.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHA98264.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHA98264.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000256|ARBA:ARBA00008535}.
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DR EMBL; JH166004; EHA98264.1; -; Genomic_DNA.
DR AlphaFoldDB; G5AMK4; -.
DR STRING; 10181.G5AMK4; -.
DR InParanoid; G5AMK4; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd01852; AIG1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903:SF180; GTPASE IMAP FAMILY MEMBER 5; 1.
DR PANTHER; PTHR10903; GTPASE, IMAP FAMILY MEMBER-RELATED; 1.
DR Pfam; PF04548; AIG1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51720; G_AIG1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT DOMAIN 25..228
FT /note="AIG1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51720"
FT COILED 246..273
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 333 AA; 36722 MW; 5EEC889B03C5B629 CRC64;
MEGLQKSVYG AMAAGGLEDN RFAVHPPLRI ILVGKTGSGK SATGNSILCR PAFQSRLRAR
SVTSSCQGEM GTWNGRSILV VDTPPIFESR AWTQETYKDI GDCYWLSAPG PHVLLLVTQL
GRFTAQDTMA VRRVKEVFGA ETMRHMVILF THKEDLGDKS LDSYVASTDN RSLQALVQEC
GRRYCAFNNR AACQEQHGQL AELRAVLDGL QCELKGCFLS NDLFLWAHVL RQGGDAAGQE
DHRRYLAQVR QQVQKQRREL NEAENNCTSI MSVLSARASA RCQECEINNA SVLLHDTHGE
ESWAILQQGK SQGIPRAASV GALAKGIPWS AQM
//
