ID G5AML4_HETGA Unreviewed; 463 AA.
AC G5AML4;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Zinc finger protein 862 {ECO:0000313|EMBL:EHA98274.1};
GN ORFNames=GW7_03471 {ECO:0000313|EMBL:EHA98274.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHA98274.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHA98274.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH166004; EHA98274.1; -; Genomic_DNA.
DR AlphaFoldDB; G5AML4; -.
DR STRING; 10181.G5AML4; -.
DR eggNOG; KOG1721; Eukaryota.
DR InParanoid; G5AML4; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd07765; KRAB_A-box; 2.
DR Gene3D; 6.10.140.140; -; 2.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR006580; Znf_TTF.
DR PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR PANTHER; PTHR23232:SF90; KRAB DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01352; KRAB; 2.
DR SMART; SM00349; KRAB; 2.
DR SMART; SM00597; ZnF_TTF; 1.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 2.
DR PROSITE; PS50805; KRAB; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..463
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003473529"
FT DOMAIN 96..162
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 414..463
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT REGION 53..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 463 AA; 50844 MW; FC300241BF0CB692 CRC64;
MPHGLGEVAA IKLLACTTLV PAQRLCALGE YYYPPTYARV KLPAALPARL GALSSGSPGP
PVGRGGSTLR PGRGGRGSTG RESGAMERRE SGKAPVTFDD ITVYLLQEEW LLLSQQQKDL
CGSDKLVAPL GATVAGPNLF GEFGRGSKPW VGDIHSQRSL LGHHSGKNQV GYMKKMDAEN
LAQDSGPYLP PLKKACLVPS SPEGDTIEGD WTGRSKKPRS IQKSWFVQFP WLIMNEEQTA
LFCSACRAYP SVRDKRSRLI EGYTGPFKVE TLKYHAKSKA HLFCVNALAA RDPIWAARFR
SIRDGSAGVL AGTEHLFPVN YPMFYPPEPL GDFDKMTKLL PSSRAELEDP ERSTAIPALY
LDCIADLRQK EISGDSHNSS NINILGDNTI EFCRQGPAEE GLLEVPVVLE KLPAMFEDVA
VYFTREEWGL LDKQQKELYR NVMQMNYELL ASLGKAPICA TIT
//
