ID G5AMR7_HETGA Unreviewed; 518 AA.
AC G5AMR7;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=Protein ERGIC-53 {ECO:0000313|EMBL:EHA98331.1};
GN ORFNames=GW7_20044 {ECO:0000313|EMBL:EHA98331.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHA98331.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHA98331.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH166046; EHA98331.1; -; Genomic_DNA.
DR AlphaFoldDB; G5AMR7; -.
DR STRING; 10181.G5AMR7; -.
DR eggNOG; KOG3838; Eukaryota.
DR InParanoid; G5AMR7; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd06902; lectin_ERGIC-53_ERGL; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR005052; Lectin_leg.
DR PANTHER; PTHR12223:SF32; PROTEIN ERGIC-53; 1.
DR PANTHER; PTHR12223; VESICULAR MANNOSE-BINDING LECTIN; 1.
DR Pfam; PF03388; Lectin_leg-like; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS51328; L_LECTIN_LIKE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..30
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 31..518
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5003473384"
FT TRANSMEM 487..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 52..275
FT /note="L-type lectin-like"
FT /evidence="ECO:0000259|PROSITE:PS51328"
FT COILED 287..314
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 518 AA; 58238 MW; F98B83B2DC245BD2 CRC64;
MAGSRGSGPQ ARLRQLSCIL LLLLSHFVGG DGTGGDPAAA GSPGTLATVL HRRFEYKYSF
KGPHLVQSDG NVPFWAHAGN AIPSSDQIRI APSLKSQRGS VWTKAKAAFE NWEVEVTFRV
TGRGRIGADG LAIWYTENQG LEGPVFGSAD MWNGVGIFFD SFDNDGKKNN PAVVIIGNNG
QIHYDHQNDG ASQALASCQR DFRNKPYPVR AKIIYYQKTL TVMINNGFTP DKNDYEFCAK
VENMIIPTQG HFGISAATGG LADDHDVLSF LTFQLTEPGK EPPTPDKEIS EKEKEKYQEE
FEHYQQELDK KKEEFQKDHP DFQGQPADEI FESVGDRELR QIFEGQNRIH LEIKQLNRQL
DMILDEQRRY VSSLTEEISK RGAVIPGQHG QVSFQNMHTV VKTQHEILRQ VNEMKNSMGE
TVRLVSGIQH PGSVGGVYET TQHFMDIKEH LHIVKRDIDN LVQRNMPSNE KPKCPELPPF
PSCLSTIHFV IFVVVQTVLF IGYIMYRTQQ EAAAKKFF
//
