ID G5AMZ0_HETGA Unreviewed; 291 AA.
AC G5AMZ0;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Gamma-sarcoglycan {ECO:0000256|ARBA:ARBA00020453};
GN ORFNames=GW7_15965 {ECO:0000313|EMBL:EHA98400.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHA98400.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHA98400.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- FUNCTION: Component of the sarcoglycan complex, a subcomplex of the
CC dystrophin-glycoprotein complex which forms a link between the F-actin
CC cytoskeleton and the extracellular matrix.
CC {ECO:0000256|ARBA:ARBA00002860}.
CC -!- SUBCELLULAR LOCATION: Cell membrane, sarcolemma
CC {ECO:0000256|ARBA:ARBA00004274}; Single-pass type II membrane protein
CC {ECO:0000256|ARBA:ARBA00004274}.
CC -!- SIMILARITY: Belongs to the sarcoglycan beta/delta/gamma/zeta family.
CC {ECO:0000256|ARBA:ARBA00007574}.
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DR EMBL; JH166109; EHA98400.1; -; Genomic_DNA.
DR AlphaFoldDB; G5AMZ0; -.
DR STRING; 10181.G5AMZ0; -.
DR eggNOG; KOG3950; Eukaryota.
DR InParanoid; G5AMZ0; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0016012; C:sarcoglycan complex; IEA:InterPro.
DR GO; GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
DR InterPro; IPR006875; Sarcoglycan.
DR InterPro; IPR039972; Sarcoglycan_gamma/delta/zeta.
DR PANTHER; PTHR12939:SF4; GAMMA-SARCOGLYCAN; 1.
DR PANTHER; PTHR12939; SARCOGLYCAN; 1.
DR Pfam; PF04790; Sarcoglycan_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..58
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 291 AA; 32487 MW; 34BB10092F385F86 CRC64;
MVREQYTAST EGTHIERPEN QYVYKIGIYG WRKRCLYLFV LLLLIILVVN FALTIWILKV
MWFSPVRMGH LRVTGDGLRL EGESEFLFPL YVKEIHSRVD SSLLLQSTQN VTMNARNSEG
EVTGRLKVGP KMVEVQNQHF QINSKDGKPL FTVDEKKVVV GTDKLRVTGP EGALFEHSVE
TPLVRADPFE DLRLESPTRS LSMDAPKGIH INALAGKIEA LSQMDIIFQS SDGMLVLDAE
TVCFPKLVQG TQGPSGSPQE LYEICVCPDG KLYLSAAGVG TTCQEHSQIC L
//
