ID   G5ANB9_HETGA            Unreviewed;       801 AA.
AC   G5ANB9;
DT   14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2011, sequence version 1.
DT   24-JAN-2024, entry version 23.
DE   RecName: Full=Protein phosphatase 1 regulatory subunit 21 {ECO:0000256|ARBA:ARBA00020102};
DE   AltName: Full=Coiled-coil domain-containing protein 128 {ECO:0000256|ARBA:ARBA00031617};
DE   AltName: Full=KLRAQ motif-containing protein 1 {ECO:0000256|ARBA:ARBA00031361};
GN   ORFNames=GW7_01005 {ECO:0000313|EMBL:EHA98529.1};
OS   Heterocephalus glaber (Naked mole rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC   Heterocephalus.
OX   NCBI_TaxID=10181 {ECO:0000313|EMBL:EHA98529.1, ECO:0000313|Proteomes:UP000006813};
RN   [1] {ECO:0000313|EMBL:EHA98529.1, ECO:0000313|Proteomes:UP000006813}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=21993625; DOI=10.1038/nature10533;
RA   Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA   Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA   Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA   Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA   Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA   Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT   "Genome sequencing reveals insights into physiology and longevity of the
RT   naked mole rat.";
RL   Nature 479:223-227(2011).
CC   -!- SUBCELLULAR LOCATION: Early endosome {ECO:0000256|ARBA:ARBA00004412}.
CC       Endosome {ECO:0000256|ARBA:ARBA00004177}.
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DR   EMBL; JH166134; EHA98529.1; -; Genomic_DNA.
DR   AlphaFoldDB; G5ANB9; -.
DR   STRING; 10181.G5ANB9; -.
DR   eggNOG; KOG4421; Eukaryota.
DR   InParanoid; G5ANB9; -.
DR   Proteomes; UP000006813; Unassembled WGS sequence.
DR   GO; GO:0005769; C:early endosome; IEA:UniProtKB-SubCell.
DR   InterPro; IPR040024; PPP1R21.
DR   InterPro; IPR049372; PPP1R21_C.
DR   InterPro; IPR019343; PPP1R21_N.
DR   InterPro; IPR019348; PPP1R21_six_helix.
DR   PANTHER; PTHR21448:SF0; PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT 21; 1.
DR   PANTHER; PTHR21448; SMOOTH MUSCLE MYOSIN HEAVY CHAIN-RELATED; 1.
DR   Pfam; PF10205; KLRAQ; 1.
DR   Pfam; PF21636; PPP1R21_C; 1.
DR   Pfam; PF10212; PPP1R21_helical; 1.
DR   SMART; SM01254; KLRAQ; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW   Endosome {ECO:0000256|ARBA:ARBA00022753};
KW   Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT   DOMAIN          11..112
FT                   /note="Protein phosphatase 1 regulatory subunit 21 N-
FT                   terminal"
FT                   /evidence="ECO:0000259|SMART:SM01254"
FT   REGION          84..104
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          3..72
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          137..196
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          558..592
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          696..737
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   801 AA;  90727 MW;  4236E9B07DE26DCE CRC64;
     MASAELQGKY QKLAQEYSKL RAQNQVLKKG VVDEQANSAA LKEQLKMKDQ SLRKLQQEMD
     SLTFRNLQLA KRVELLQDEL ALSEPRGKKN KKSGESSSQL SQEQKSVFDE DLQKKIEENE
     RLHIQFFEAD EQHKHVEAEL RSRLATLETE AAQHQAVVDG LTQKYMETIE KLQNDKAKLE
     VKSQTLEKEA KECRLRTEEC QLQLKNLHED LSGRLEESLS VINEKVPFND TRCSQYNALN
     VPLHNRRHQL KMRDIARQAL AFVQDLVTAL LNFHTYTEQR IQIFPVDSAI DTISPLNQKF
     SQYLHENASY VRPLEEGMLH LFESITEDTV TVLETTVKLK TFSEHLTSYI CFLRKILPYQ
     LKSLEEECES SLCTSALRAR NLELSQDMRR MTAVFEKLQT YVALLSLPST QPDGLVRTNY
     SSVLTNVGAA LHGFHDVMKD ISKHYSQKAT IEHELPTATQ KLITTNDCIL SSVVALTNGA
     GKMASFFSNN VDCFIASLSY GPQAASRFTS PPAAACMLQY KKRAAAYMKA LRKPLPESVP
     YEEALADRRV LLSSTESREG LAQQVQQSLE KISKLEQEKE HWMLEAQLAK IKLEKENQRI
     VDKLKSTSSG QLAGLAQEST VVVTTAVQDE AMAKASLEPV QSTGLIGILT RTSDSEVPDA
     ESREDLIKNH YMARVVELTS QLQLADSKSV HFYAECRALS KRLVLAEKSK ETLTEEIKVA
     SQNITRLQDE LTTTKRSYED QLSMMSDHLC SMNETLSKQR EEIDTLKMSS KVCEVWHLQG
     NDMVKRVVSL PCTSGTEGYE I
//