ID G5AR24_HETGA Unreviewed; 537 AA.
AC G5AR24;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 38.
DE SubName: Full=Protein arginine N-methyltransferase 3 {ECO:0000313|EMBL:EHA99484.1};
GN ORFNames=GW7_06383 {ECO:0000313|EMBL:EHA99484.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHA99484.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHA99484.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JH166511; EHA99484.1; -; Genomic_DNA.
DR AlphaFoldDB; G5AR24; -.
DR STRING; 10181.G5AR24; -.
DR InParanoid; G5AR24; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0016274; F:protein-arginine N-methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 2.70.160.11; Hnrnp arginine n-methyltransferase1; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR025799; Arg_MeTrfase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR11006; PROTEIN ARGININE N-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR11006:SF114; PROTEIN ARGININE N-METHYLTRANSFERASE 3; 1.
DR Pfam; PF06325; PrmA; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51678; SAM_MT_PRMT; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|PROSITE-ProRule:PRU01015,
KW ECO:0000313|EMBL:EHA99484.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01015};
KW Transferase {ECO:0000256|PROSITE-ProRule:PRU01015,
KW ECO:0000313|EMBL:EHA99484.1}.
FT REGION 1..53
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 72..111
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 84..106
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 537 AA; 58919 MW; 13015BF7F64ADBF9 CRC64;
MRTAAGQHPR PHTSEGTRTP ALARATSPPP ERALPSARPR AAGSAGDPKP TAQRLRRLST
AGLKAAGRYF LSRPGGRGAV EEEDDLPELS DSGDDAAWED DDEADPPHDG QQTPCLFCNR
FVRLALVLPG AALGVGDGCW RRKALLGVEG GALRCSPDVE DLYEPVSVPF SYPNGLSENT
SVVERLKHME ARALSAEAAL AGAREELQRM RQFAQDFVMN ADVRTCSSST AIADLQEDED
GVYFSSYGHY GIHEEMLKDK VRTESYRDFI YQNPHIFKDK VVLDVGCGTG ILSMFAAKAG
ARKVLGVDQS EILYQAMDII RLNKLEDTIV LIKGKIEEVH LPVEKVDVIV SEWMGYFLLF
ESMLDSVLYA KNKYLAKGGS VYPDICTISL VAVSDVSRHA DRIAFWDDVY GFNMSCMKKA
VIPEAVVEVL DPKTLISDSC GIKHIDCHTT SISDLEFSSD FSLKITKTSM CTVVFSTGPQ
STKTHWKQTV FLLEKPFSVK AGDSLKGKVT VHKNKKDPRS LIVTLTVNSS TQTYGLQ
//
