ID G5AS56_HETGA Unreviewed; 355 AA.
AC G5AS56;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE SubName: Full=Paired box protein Pax-5 {ECO:0000313|EMBL:EHA99866.1};
DE Flags: Fragment;
GN ORFNames=GW7_10562 {ECO:0000313|EMBL:EHA99866.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHA99866.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHA99866.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
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DR EMBL; JH166726; EHA99866.1; -; Genomic_DNA.
DR AlphaFoldDB; G5AS56; -.
DR STRING; 10181.G5AS56; -.
DR eggNOG; KOG3862; Eukaryota.
DR InParanoid; G5AS56; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd00131; PAX; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR043182; PAIRED_DNA-bd_dom.
DR InterPro; IPR001523; Paired_dom.
DR InterPro; IPR022130; Pax2_C.
DR InterPro; IPR043565; PAX_fam.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR45636:SF20; PAIRED BOX PROTEIN PAX-5; 1.
DR PANTHER; PTHR45636; PAIRED BOX PROTEIN PAX-6-RELATED-RELATED; 1.
DR Pfam; PF00292; PAX; 1.
DR Pfam; PF12403; Pax2_C; 1.
DR PRINTS; PR00027; PAIREDBOX.
DR SMART; SM00351; PAX; 1.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR PROSITE; PS00034; PAIRED_1; 1.
DR PROSITE; PS51057; PAIRED_2; 1.
PE 4: Predicted;
KW Paired box {ECO:0000256|ARBA:ARBA00022724};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 4..130
FT /note="Paired"
FT /evidence="ECO:0000259|PROSITE:PS51057"
FT REGION 170..206
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHA99866.1"
FT NON_TER 355
FT /evidence="ECO:0000313|EMBL:EHA99866.1"
SQ SEQUENCE 355 AA; 38181 MW; F1FB3995434F3D2A CRC64;
SVSGHGGVNQ LGGVFVNGRP LPDVVRQRIV ELAHQGVRPC DISRQLRVSH GCVSKILGRY
YETGSIKPGV IGGSKPKVAT PKVVEKIAEY KRQNPTMFAW EIRDRLLAER VCDNDTVPSV
SSINRIIRTK VQQPPNQPVP ASSHSIVSTG SVTQVSSVST DSAGSSYSIS GILGITSPSA
DTNKRKRDEG IQESPVPNGH SLPGRDFLRK QMRGDLFTQQ QLEVLDRVFE RQHYSDIFTT
TEPIKPEQTT EYSAMASLAG GLDDMKANLT SPTPADIGSS VPGPQSYPIV TGRDLASTTL
PGYPPHVPPA GQGSYSAPTL TGMVPGSEFS GSPYSHPQYS SYNDSWRFPN PGLLG
//
