ID G5AUL2_HETGA Unreviewed; 447 AA.
AC G5AUL2;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=SH2 domain-containing protein 7 {ECO:0000313|EMBL:EHB00723.1};
GN ORFNames=GW7_10870 {ECO:0000313|EMBL:EHB00723.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB00723.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB00723.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH167034; EHB00723.1; -; Genomic_DNA.
DR AlphaFoldDB; G5AUL2; -.
DR STRING; 10181.G5AUL2; -.
DR eggNOG; ENOG502QUGN; Eukaryota.
DR InParanoid; G5AUL2; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR CDD; cd10417; SH2_SH2D7; 1.
DR Gene3D; 3.30.505.10; SH2 domain; 1.
DR InterPro; IPR000980; SH2.
DR InterPro; IPR036860; SH2_dom_sf.
DR InterPro; IPR035885; SH2D7_SH2.
DR PANTHER; PTHR14388:SF6; SH2 DOMAIN-CONTAINING PROTEIN 7; 1.
DR PANTHER; PTHR14388; T CELL-SPECIFIC ADAPTER PROTEIN TSAD; 1.
DR Pfam; PF00017; SH2; 1.
DR PRINTS; PR00401; SH2DOMAIN.
DR SMART; SM00252; SH2; 1.
DR SUPFAM; SSF55550; SH2 domain; 1.
DR PROSITE; PS50001; SH2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT DOMAIN 48..139
FT /note="SH2"
FT /evidence="ECO:0000259|PROSITE:PS50001"
FT REGION 208..228
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 261..301
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 447 AA; 48837 MW; FDE62E7C770A60EE CRC64;
MEGSLEQPGP GKGPGDSQAL AELQELALKW FMETQAPSIL QNGALPPWFH GFVTRKQTEQ
LLCDKALGSF LIRLSDRAAS YILSYRGSDR CRHFVINQLR NRRYLVSGDN LSHGTLAELV
RHYQEVQLEP FGETLAAACP RVEDHDLYDA ITLGLQQTNL GLENLPATSP AMVPDKAASP
RVPVKARGSF LHTEKSLDPG PWNLAKEDST EVHSRVPPLP ERSASLLDKS PAMPGNLIYM
DLRKTSQARL GVGTAVSSQA CAPGRETLQR LSDGDQDRPD NLGPTLPGLN PDQGPKMPAT
SRGPLLYPSS EAQGSWAATR RQGFQQLSHA ALSCSQGSFA DASDLAGATG LLQEACDTAD
QEERAYEQIP AHRSGPDRLP PLRASPTYST LSGPMNSGYE RTSGTLELPE LGNTYEQIPA
ARRKEPGRTQ KPDKLRRLFF ADKKHRF
//
