ID G5AUS6_HETGA Unreviewed; 332 AA.
AC G5AUS6;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 48.
DE RecName: Full=Nuclear migration protein nudC {ECO:0000256|ARBA:ARBA00017641};
DE AltName: Full=Nuclear distribution protein C homolog {ECO:0000256|ARBA:ARBA00030427};
GN Name=NUDC {ECO:0000313|EMBL:JAO02970.1};
GN ORFNames=GW7_08426 {ECO:0000313|EMBL:EHB00787.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB00787.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB00787.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
RN [2] {ECO:0000313|EMBL:JAO02970.1}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Kidney {ECO:0000313|EMBL:JAO02970.1};
RA Bens M., Sahm A., Jahn N., Morhart M., Holtze S., Hildebrandt T.B.,
RA Platzer M., Szafranski K.;
RT "FRAMA: From RNA-seq data to annotated mRNA assemblies.";
RL Submitted (OCT-2015) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}. Midbody
CC {ECO:0000256|ARBA:ARBA00004214}.
CC -!- SIMILARITY: Belongs to the nudC family.
CC {ECO:0000256|ARBA:ARBA00010513}.
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DR EMBL; JH167040; EHB00787.1; -; Genomic_DNA.
DR EMBL; GEBF01000663; JAO02970.1; -; Transcribed_RNA.
DR RefSeq; XP_004850737.2; XM_004850680.2.
DR AlphaFoldDB; G5AUS6; -.
DR STRING; 10181.G5AUS6; -.
DR GeneID; 101720892; -.
DR KEGG; hgl:101720892; -.
DR CTD; 10726; -.
DR eggNOG; KOG2265; Eukaryota.
DR InParanoid; G5AUS6; -.
DR OMA; QDGPRIQ; -.
DR OrthoDB; 141208at2759; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR Bgee; ENSHGLG00000011404; Expressed in ovary and 10 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0030496; C:midbody; IEA:UniProtKB-SubCell.
DR GO; GO:0072686; C:mitotic spindle; IEA:Ensembl.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007080; P:mitotic metaphase chromosome alignment; IEA:Ensembl.
DR GO; GO:0007052; P:mitotic spindle organization; IEA:Ensembl.
DR CDD; cd06492; p23_mNUDC_like; 1.
DR Gene3D; 2.60.40.790; -; 1.
DR InterPro; IPR007052; CS_dom.
DR InterPro; IPR008978; HSP20-like_chaperone.
DR InterPro; IPR032572; NuDC.
DR InterPro; IPR037898; NudC_fam.
DR InterPro; IPR025934; NudC_N_dom.
DR PANTHER; PTHR12356:SF3; NUCLEAR MIGRATION PROTEIN NUDC; 1.
DR PANTHER; PTHR12356; NUCLEAR MOVEMENT PROTEIN NUDC; 1.
DR Pfam; PF04969; CS; 1.
DR Pfam; PF16273; NuDC; 1.
DR Pfam; PF14050; Nudc_N; 1.
DR SUPFAM; SSF49764; HSP20-like chaperones; 1.
DR PROSITE; PS51203; CS; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306};
KW Cell division {ECO:0000256|ARBA:ARBA00022618};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Mitosis {ECO:0000256|ARBA:ARBA00022776};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT DOMAIN 168..259
FT /note="CS"
FT /evidence="ECO:0000259|PROSITE:PS51203"
FT REGION 67..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 128..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 67..94
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 332 AA; 38308 MW; 140BCF5D92C00C96 CRC64;
MGGEQEEERF DGMLLAMAQQ HEGGVQELVN TFFSFLRRKT DFFVGGEEGM AEKLITQTFN
HHNQLAQKAR QEKRARQETE RREKAERAAR LAKEAKAENS GPQIQELTDE EAERLQLELD
KKKDAENHEA QLKNGSIGPP EKQESAEDEE EEDEKDKGKL KPNLGNGADL PNYRWTQTLS
ELDLAVPFHV NFRLKGKDVV VDIQRRHLRV GLKGQPAVID GELYNEVKVE ESSWLIEDSK
VVTVHLEKIN KMEWWSRLVS GDPEINTKKI NPENSKLSDL DSETRSMVEK MMYDQRQKSM
GLPTSDEQKK QEILKKFMDQ HPEMDFSKAK FN
//
