ID G5AVC7_HETGA Unreviewed; 927 AA.
AC G5AVC7;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE RecName: Full=PAX-interacting protein 1 {ECO:0000256|ARBA:ARBA00023858};
DE AltName: Full=PAX transactivation activation domain-interacting protein {ECO:0000256|ARBA:ARBA00030146};
DE Flags: Fragment;
GN ORFNames=GW7_09060 {ECO:0000313|EMBL:EHB00988.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB00988.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB00988.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH167077; EHB00988.1; -; Genomic_DNA.
DR AlphaFoldDB; G5AVC7; -.
DR STRING; 10181.G5AVC7; -.
DR eggNOG; KOG2043; Eukaryota.
DR InParanoid; G5AVC7; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0043229; C:intracellular organelle; IEA:UniProt.
DR CDD; cd17714; BRCT_PAXIP1_rpt1; 1.
DR CDD; cd17710; BRCT_PAXIP1_rpt2; 1.
DR CDD; cd17711; BRCT_PAXIP1_rpt3; 1.
DR CDD; cd17730; BRCT_PAXIP1_rpt4; 1.
DR CDD; cd17712; BRCT_PAXIP1_rpt5; 1.
DR CDD; cd18440; BRCT_PAXIP1_rpt6; 1.
DR Gene3D; 3.40.50.10190; BRCT domain; 5.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR PANTHER; PTHR23196; PAX TRANSCRIPTION ACTIVATION DOMAIN INTERACTING PROTEIN; 1.
DR PANTHER; PTHR23196:SF37; PAX-INTERACTING PROTEIN 1; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF16589; BRCT_2; 1.
DR Pfam; PF12738; PTCB-BRCT; 2.
DR Pfam; PF16770; RTT107_BRCT_5; 1.
DR SMART; SM00292; BRCT; 5.
DR SUPFAM; SSF52113; BRCT domain; 5.
DR PROSITE; PS50172; BRCT; 5.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT DOMAIN 1..67
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 68..157
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 462..555
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 572..633
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT DOMAIN 727..808
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
FT REGION 155..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 344..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 696..717
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 163..184
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 188..205
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 373..387
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 399..420
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHB00988.1"
FT NON_TER 927
FT /evidence="ECO:0000313|EMBL:EHB00988.1"
SQ SEQUENCE 927 AA; 103048 MW; 5CDA9D6CB109AA85 CRC64;
KVIQLLKAGK AKEVSYNALA SHIISEDGDN PEVGEAREVF DLPVVKPSWV ILSVQCGALL
PVNGFSPESC QIFFGVTACL SQVSSEDRSA LWALVTFHGG NCQLNLNKKC THLIVPEPKG
EKYECAVKRA SIKVVTPDWV LDCVSEKTRK DEAPYHPRLI IYEEEEEEEE EEEEEGENEE
QDSQNEGSTE EKSSPASSQE GSPSRDQPFL PKPSAETSKG ELMFDDSSDS SPEKQERNLN
WTPAEVPHPT AAKRRLPQGK EAGLINLCAN VPPVPGNILP PDVRGNFMAS GQTLQSSERA
EMITTWSPAV RTLRNITNNA DIQQINRPSD VAHILQSLSA PTKALEPQVG HGQQGHGSAS
TGAMLLGPTR GAPDTHLPPP HRQPLPQHPL QHPVLHLQPP QMPQQPCPQQ QHPFPQQPHP
AAPHLGQAAP AMQHQPPHLQ PPPPQQPPQL PLCGHDPAVE IPEEAFLLGC VFAIAEYPEQ
MSDKQLLATW KRIIQAHGGV VDPTFTSRCT HLLCESQVSS MYAQAIRERK RCVTAHWLNT
ILKRKKMVPP HRALHFPVAF PPGGKPCSQH IISVTGFVDS DRNDLKLMAY LAGAKYTGYL
CRSNTVLICK EPSGLKYEKA KEWRIPCVNA QWLGDILLGN FEALRQIQYG RYTAFNLQDP
FAPTQHLVLN LLDAWRVPLK VSPELLMGVR LPPKPKQNEV SSIQPSSKRA RIEDLPPPTK
KLTPELTPFV LFTGFEPGQV QQYIKKLYVL GGEVAESAQK CTHLIASKVT RTVKFLTAIS
VVQHIVTPEW LEECFKCQKF VDEQNYILRD AEAEVLFSFS LEESLKRAHV APLFKAKYFY
ITPGICPSLS TMKAIVECAG GKVLSKQPSF RKLVEHKQNK SLSEIIVISC ENDLHLCREY
FARGIDVHNA EFVLTGVLTQ TMDYESY
//
