ID G5AWV7_HETGA Unreviewed; 4485 AA.
AC G5AWV7;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 54.
DE SubName: Full=Low-density lipoprotein receptor-related protein 1B {ECO:0000313|EMBL:EHB01516.1};
DE Flags: Fragment;
GN ORFNames=GW7_14165 {ECO:0000313|EMBL:EHB01516.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB01516.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB01516.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- SIMILARITY: Belongs to the LDLR family.
CC {ECO:0000256|ARBA:ARBA00009939}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; JH167273; EHB01516.1; -; Genomic_DNA.
DR STRING; 10181.G5AWV7; -.
DR eggNOG; KOG1215; Eukaryota.
DR InParanoid; G5AWV7; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00112; LDLa; 29.
DR Gene3D; 2.10.25.10; Laminin; 13.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 30.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 8.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR000033; LDLR_classB_rpt.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR22722:SF5; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 1B; 1.
DR PANTHER; PTHR22722; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF00008; EGF; 1.
DR Pfam; PF07645; EGF_CA; 2.
DR Pfam; PF14670; FXa_inhibition; 5.
DR Pfam; PF00057; Ldl_recept_a; 28.
DR Pfam; PF00058; Ldl_recept_b; 14.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00181; EGF; 26.
DR SMART; SM00179; EGF_CA; 5.
DR SMART; SM00192; LDLa; 30.
DR SMART; SM00135; LY; 35.
DR SUPFAM; SSF57196; EGF/Laminin; 4.
DR SUPFAM; SSF57184; Growth factor receptor domain; 4.
DR SUPFAM; SSF57424; LDL receptor-like module; 30.
DR SUPFAM; SSF63825; YWTD domain; 8.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 4.
DR PROSITE; PS01186; EGF_2; 4.
DR PROSITE; PS50026; EGF_3; 5.
DR PROSITE; PS01187; EGF_CA; 3.
DR PROSITE; PS01209; LDLRA_1; 13.
DR PROSITE; PS50068; LDLRA_2; 30.
DR PROSITE; PS51120; LDLRB; 19.
PE 3: Inferred from homology;
KW Calcium {ECO:0000256|ARBA:ARBA00022837};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Lipoprotein {ECO:0000313|EMBL:EHB01516.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000313|EMBL:EHB01516.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 4330..4353
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REPEAT 181..223
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 224..267
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 454..496
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 497..542
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 543..592
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1187..1233
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1234..1276
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1277..1323
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1324..1368
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1505..1547
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1592..1631
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1809..1851
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1852..1894
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 1895..1938
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 2217..2261
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 2262..2304
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 2986..3028
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 3029..3072
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT REPEAT 3925..3968
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DOMAIN 4099..4132
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 4135..4171
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 4172..4207
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 4208..4243
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 4278..4313
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 735..747
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 742..760
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 776..788
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 783..801
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 817..829
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 824..842
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 893..905
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 900..918
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 960..975
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 1003..1018
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2405..2423
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2439..2451
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2446..2464
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2458..2473
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2478..2490
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2485..2503
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2497..2512
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2546..2561
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2569..2581
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2576..2594
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2588..2603
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2607..2619
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2614..2632
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2692..2704
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2699..2717
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2732..2744
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2778..2790
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2785..2803
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 2797..2812
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3204..3216
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3211..3229
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3244..3256
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3251..3269
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3263..3278
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3303..3318
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3343..3358
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3363..3375
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3370..3388
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3382..3397
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3402..3414
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3409..3427
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3421..3436
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3440..3452
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3447..3465
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3459..3474
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3481..3493
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3488..3506
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3500..3515
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3539..3554
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3561..3573
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3568..3586
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3623..3638
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3648..3660
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3655..3673
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 3667..3682
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 4103..4113
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4139..4149
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4161..4170
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4175..4185
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4197..4206
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4211..4221
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4233..4242
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4280..4290
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4284..4301
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 4303..4312
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHB01516.1"
SQ SEQUENCE 4485 AA; 503082 MW; 4CDFDD52D4AC6224 CRC64;
ELLPNCQQLN CQYKCALIRN RTRCYCEDGF EVKEDGRSCK DQDECAVYGT CSQTCVNTHG
SYACGCAEGY IMQPNNRSCK AKNEPTDKPP MLLIANSETI EIFHLNGSKT ATLNPVNRNE
IHTLDFIYEE EIICWVESRD TSNQLKCLQI TKTGKLMDEW TINILQSFHN VEQMAIDWLT
RNLYFVDHVS DRIFVCNFNG SVCVTLLDLD LHNPKAIAVD PIAGKLFFTD YGNVAKVERC
DMDGVNRTRI IDSKTEQPAA LALDLVNKLV YWVDLYLDYI GVVDYQGKSR HTIIQGRQVR
HLYGITVFED YLYATSSDNF NIIRINRFNA TDVYSLIKME KARGIRIFQK RTQPTVRSHA
CEVDPYGMPG GCSHICLLSG SYKTRTCRCR TGFNLGSDGR SCKRPKNELF LFYGKGRPGI
VRGMDLNTKI ADEYMIPIEN LVNPRAVDFH AETNYIYFAD TTSFLIGRQK IDGTERETIL
KDDLDNVEGI AVDWIGDNLY WTNDGHRKTI NVARLEKASQ SRKTLLEGEM SHPRGIVVDP
VNGWMYWTDW EEDEIDASVG RIEKAWMDGF NRQIFVTSKM LWPNGLTLDF QASMLYWCDA
YYDHIEKVFL NGTHRKWERG EPSKKKELNH PFGLSHHGNY VFWTDYMNGS IFQLDLVTSE
VTLLRHERPP LFGLQIYDPR KQQGDNMCRV NNGGCSTLCL ATPAGRVCAC ADNQLLDENG
TTCTFNPGEV LPRTCKAGEF RCRNRHCIQA RWECDGDDDC LDGSDEDPIN CFNHSCPDDQ
FKCQNNRCIP KRWLCDGAND CGSNEDESNQ TCTARTCQVD QFSCGNGRCI PRAWLCDTED
DCGDQTDEMA TCEFPTCEPL TQFVCKSGRC ISSKWHYDDC GDGSDELGCV HSCFDSQFRC
SSGRCIPGHW ACDGDNDCGD FSDETQANCT KEEIQSPAGC NGNEFQCYPD GNCIPDLWRC
DGEKDCEDGS DEKGCNGTIR LCDYKTKFSC QSTGRCINKA WVCDGDIDCE DQSDEEDCDS
FLCGPPKYPC ANDTSVCLQP EKLCNGKRDC PDGSDEGDLC DECSLNNGGC SNHCSVVPGR
GIVCSCPEGL QLNKDNKTCE IVDYCSSHLK CSQVCEQHKH MVKCSCYEGW KLDPDGESCT
SVDPFEAFII FSIRHEIRRI DLHKRDYSLL VPGLRNTIAL DFHFNQSLLY WTDVVEDRIY
RGKLSENGGV SAIEVVVEHG LATPEGLTVD WIAGNIYWID SNLDQIEVAK LDGSLRTTLI
AGGMEHPRAI ALDPRFGILF WTDWDANFPR IESASMSGAG RKTIYKDMKT GAWPNGLTVD
HFEKRIVWTD ARSDAIYSAL YDGTNMIEII RGHEYLSHPF AVSLYGSEVY WTDWRTNTLS
KANKWTGQNV SVIQKTSAQP FDLQIYHPSR QPQAPNPCIA NEGRGPCSHL CLINHNLSAA
CACPHLMKLS SDQKTCYEMK KFLLYARHSE IRGVDIDNPY FNFITAFTVP DIDDVTVIDF
DASEERLYWT DIKTQTIKRA FINGTGLETV ISRDIQSIRG LAVDWVSRNL YWISSEFDET
QINVARLDGS LKTSIIHGID KPQCLAAHPI RGKLYWTDGN TINMANMDGS NSKILFQNQK
EPVGLSIDYA ENKLYWISSG NGTINRCNLD GGNLEVIESM KEELTKATAL TIMDKKLWWA
DQNLAQLGTC NKRDGRNPTI LRNKTSAVVH MKVYDKEAQQ GSNSCHLNNG GCSQLCLPTS
ENTRTCMCTV GYYLQKNRMS CQGIESFLMY SVHEGIRGIP LEPSDKMDAL MPISGTSFAV
GIDFHAENDT IYWTDMGFNK ISRAKRDQTW KEDIITNGLG RVEGIAIDWI AGNMYWTDHG
FNLIEVARLN GSFRYVIISQ GLDQPRSIAV HPEKGFLFWT EWGQMPCIGK ARLDGSEKLV
LVSMGIVWPN GISIDYEENK LYWCDARTDK IERIDLETGG NREMVLSGSN VDMFSVAVFG
AYVYWSDRAH ANGSIRRGHK NDPTEMVTMR TGLGVNLKEI KIFNRVREKG TNVCAKDNGG
CKQLCLYRGN SRRTCACAHG YLAEDGVTCL RHEGYLLYSG RTVLKSIHLS DETNLNSPIR
PYGNPHYFKN VIALAFDYNQ RRKGTNRIFY SDAHFGNIQL IKDNWEDRQV IVENVGSVEG
LAYHRAWDTL YWTSSTTSSI TRHTVDQTRP GAFDREAVIT MSEDDHPHVL ALDECQNLMF
WTNWNEQHPS IMRSTLTGKN AQVVVSSDIL TPNGLTIDHR AEKLYFSDGS LGKIERCEYD
GSQRHVIVKS GPGTFLSLAV YDNYIFWSDW GRRAILRSNK YTGGDTKILR SDIPHQPMGI
IAVASDTNSC ELSPCAVLNG GCHDLCLLTP DGRVNCSCRG DRILLDDNRC VTKNSSCNIY
SDFECGNGEC IGYQLTCDGT PHCKDKSDEK LLYCENRSCR RGFQPCYNRR CVPHAKLCDG
EDDCGDNSDE LDCKVSTCAT VEFRCADGTC IPRSARCNQN VDCADASDEK NCNNTDCTHF
YKLGVKTAGF IKCNSTSLCV LPTWICDGSN DCGDYSDELK CPVQNKHKCE ENYFGCPSGR
CILNTWLCDG QKDCEDGLDE LHCDSSCSWS QFACSAHKCI SKHWICDGED DCGDGLDESD
SICGDVTCAA DMFSCQGSRA CVPRHWLCDG ERDCPDGSDE LSTAGCAPNN TCDENTFMCH
NKVCIPKQFV CDHDDDCGDA SDEPLKCGYR QCGAEEFRCA DGRCLLNTQW QCDRDFDCPD
HSDEAPLNPK CKNAEQSCNS SFFMCQNGRC IPSGRLCDNK DDCGDGSDER NCHINECLSK
KTSGCSQDCQ DLPISYKCKC WPGFQLKDDG KTCVDIDECS SGFPCSQQCI NTYGTYKCLC
TDGYKIQPDN PNGCKSLSDE EPFLILADHH EIRKISTDGS NYTLLKQGLN NVIAIDFDYR
EEFIYWIDSS RPNGSRINRM CLNGSDIKVV HNTAVPNALA VDWIGKNLYW SDMEKRIIEV
SKVNGLYPTI LVSKRLKFPR DLSLDPRAGY LYWIDCCEYP HIGRVGMDGS NQSVVIETRI
SRPMALTIDY VNDRLYWADE NHIEFSNMDG SHRNKVPNQD IPGVIALTLF EDYVYWTDGK
TKSLSRAHKT SGADRLSLVN SWHTIADIQV YHSYRQPDVS KHLCMINNGG CSHLCLLAPG
KSHTCACPTN FYLAADNRTC LSNCTASQFR CKTDKCIPFW WKCDTVDDCG DGSDEPDDCP
EFKCQPGRFQ CGTGLCALPA FICDGENDCG DNSDELNCDT HVCLSGQFKC TKKRKCIPVN
LRCNGKDDCG DEEDERDCPE NSCSPDYFQC KTTKHCISKL WVCDEDPDCA DASDEANCDK
KTCGPHEFQC KNSNCIPDHW RCDSQNDCSD NSDEENCKPQ TCTLKDFLCA NGDCVSSRFW
CDGDFDCADG SDERNCAISC SKDQFQCSNG QCISAKWKCD GHEDCKYGED ERNCEPASPS
CSSSEYICIS GGCISASLKC NGEYDCADGS DEMDCVTECK EDQFRCKNKA HCIPVRWLCD
GIHDCVDGSD EEICDRGGNI CRADEFLCNN SLCKLYFWVC DGQDDCGDNS DESPDMCVKF
LCPPTRPHRC RNNRICLQSE KPCNGVDDCG DNSDEDHCGK DTYKAKPCKK DEFACSNKKC
IPMDLQCDRL DDCGDGSDEQ GCRTTPTEYT CEDNVNPCGD DAYCNQIKTS VFCRCKPGFQ
RNMKNRQCED LNECLVFGTC SQQCINIHGS YKCVCDQNFQ AQNNTCIAKG SEDQVLYIAN
DTDILGFIYP FNYSGDHQQI SHIEHNSRIT GMDVYYQRDM IIWSTQFNPG GIFYKMIHGR
EKRQANSGLI CPEFKRPRDI AVDWVAGNIY WTDHSRMHWF SYYTTHWTSL RYSVNVGQLN
GSNCTRLLTN MAGEPYAIAV HPKRGMMYWT VIGDHSHIEE AAMDGTLRRI LVQKNLQRPT
GLAVDHFTER IYWADFELSI IGSVLYDGSD SVVSVSSKQG LLHPHRIDIF EDYIYGAGPK
HGVFRVQKFG HGSVEYLALH VDKTKGVLIS HRYKQLDLPN PCSDLACEFL CLLNPSGAAC
VCPEGKYLIN GSCSDDSLLD DSCKLICENG GRCILNEKGD ERCHCWPSYS GERCEVNHCS
NYCQNGGSCT PSSLGRPTCS CALGFTGPNC GKTVCEDFCQ NGGTCIVTTG NQPHCHCHAE
YTGDRCQYYV CHHYCVNSES CSIGNDGSVE CVCPTRYEGP KCEVDKCVRC HGGHCIINKD
NEDIFCNCTN GKIASSCQLC DGYCYNGGTC QLDPETNVPV CLCSTNWSGT QCERPAPKSS
KSDHISTRSI AIVVPLVLLV TLITTLVIGL VLCKRKRRTK TIRRQPIING GINVEIGNPS
YNMYEVDHDH NDGTLLDPGF MVDPTKARYI GGGPSAFKLS HTVPPIYLNS DLKGPLTAGP
TNYSNPVYAK LYMDGQTCRN SLGSVDERKE LLPKKIEIGI RETVA
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