ID G5AZ23_HETGA Unreviewed; 423 AA.
AC G5AZ23;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE SubName: Full=Tripartite motif-containing protein 14 {ECO:0000313|EMBL:EHB02293.1};
DE Flags: Fragment;
GN ORFNames=GW7_05040 {ECO:0000313|EMBL:EHB02293.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB02293.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB02293.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH167586; EHB02293.1; -; Genomic_DNA.
DR AlphaFoldDB; G5AZ23; -.
DR STRING; 10181.G5AZ23; -.
DR eggNOG; ENOG502QTZS; Eukaryota.
DR InParanoid; G5AZ23; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0045087; P:innate immune response; IEA:InterPro.
DR CDD; cd19768; Bbox2_TRIM14; 1.
DR CDD; cd13738; SPRY_PRY_TRIM14; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR003879; Butyrophylin_SPRY.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR006574; PRY.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR044116; SPRY_PRY_TRIM14.
DR InterPro; IPR000315; Znf_B-box.
DR PANTHER; PTHR25465:SF11; B BOX-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR25465; B-BOX DOMAIN CONTAINING; 1.
DR Pfam; PF13765; PRY; 1.
DR Pfam; PF00622; SPRY; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR PRINTS; PR01407; BUTYPHLNCDUF.
DR SMART; SM00336; BBOX; 1.
DR SMART; SM00589; PRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00024};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00024};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00024}.
FT DOMAIN 7..44
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 230..423
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHB02293.1"
SQ SEQUENCE 423 AA; 48300 MW; 2DF6D3A90FF9B44E CRC64;
ETCSWRCSEH GGRPVELFCR RCGRCVCALC PVLGGHRGHP VALARDEAAR VQKLIQECLE
HLATKKQQHV GNITQIEVVT EKLKAKSSKA WLKEKFTELR LLLDEEEVLA KKFVDKNMQL
ALQGYREQAE SCEKQVDVMN ELSSRIWSIG QEPNPIQLLQ AYTAIELEMQ RHMSLPELSH
PVPQSFEPVK SFFKDFTEAM QSMLQTPLDI RLKENLKCQL SGSSSTKPGT LLKISPSPER
SLLLKYARTP TLDPDTMHAR LRLSADRLTL RCGLVGSLGP TPALRFDKLW QVLGRDCFAA
GRHYWEVDVQ EAGCGWWVGA AYPSLRRRGA TAAARLGCNR QSWCLKRYDL EYWAFHDCQR
SRLRPRGDPD RLGVFLDYEA GVLAFYDVRD GMRHLHTFHD SFQEPLYPAL RLWEGTISIP
RLP
//
