ID G5B0A2_HETGA Unreviewed; 72 AA.
AC G5B0A2;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 24.
DE SubName: Full=Eukaryotic translation initiation factor 4E-binding protein 1 {ECO:0000313|EMBL:EHB02713.1};
DE Flags: Fragment;
GN ORFNames=GW7_01216 {ECO:0000313|EMBL:EHB02713.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB02713.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB02713.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SIMILARITY: Belongs to the eIF4E-binding protein family.
CC {ECO:0000256|ARBA:ARBA00005480}.
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DR EMBL; JH167805; EHB02713.1; -; Genomic_DNA.
DR AlphaFoldDB; G5B0A2; -.
DR STRING; 10181.G5B0A2; -.
DR eggNOG; ENOG502S4SY; Eukaryota.
DR InParanoid; G5B0A2; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0008190; F:eukaryotic initiation factor 4E binding; IEA:InterPro.
DR GO; GO:0003743; F:translation initiation factor activity; IEA:UniProtKB-KW.
DR GO; GO:0045947; P:negative regulation of translational initiation; IEA:InterPro.
DR InterPro; IPR008606; EIF4EBP.
DR PANTHER; PTHR12669; EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN; 1.
DR PANTHER; PTHR12669:SF14; EUKARYOTIC TRANSLATION INITIATION FACTOR 4E-BINDING PROTEIN 1; 1.
DR Pfam; PF05456; eIF_4EBP; 1.
PE 3: Inferred from homology;
KW Initiation factor {ECO:0000313|EMBL:EHB02713.1};
KW Protein biosynthesis {ECO:0000313|EMBL:EHB02713.1};
KW Protein synthesis inhibitor {ECO:0000256|ARBA:ARBA00023193};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Translation regulation {ECO:0000256|ARBA:ARBA00022845}.
FT REGION 19..72
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 33..56
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:EHB02713.1"
SQ SEQUENCE 72 AA; 7920 MW; A0448D07C1F7B793 CRC64;
PAGTRIIYDR KFLMECRNSP VAKTPPRDLP TIPGVTSPSS DEPSMEASQS HLRSSLEDKP
AGSEESQFEM DI
//
