ID G5B0Z2_HETGA Unreviewed; 625 AA.
AC G5B0Z2;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE SubName: Full=Interferon-induced protein with tetratricopeptide repeats 1-like protein {ECO:0000313|EMBL:EHB02953.1};
GN ORFNames=GW7_17423 {ECO:0000313|EMBL:EHB02953.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB02953.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB02953.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- SIMILARITY: Belongs to the IFIT family.
CC {ECO:0000256|ARBA:ARBA00038336}.
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DR EMBL; JH167911; EHB02953.1; -; Genomic_DNA.
DR AlphaFoldDB; G5B0Z2; -.
DR STRING; 10181.G5B0Z2; -.
DR eggNOG; KOG1124; Eukaryota.
DR InParanoid; G5B0Z2; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0051707; P:response to other organism; IEA:UniProt.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR10271; INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS; 1.
DR PANTHER; PTHR10271:SF16; INTERFERON-INDUCED PROTEIN WITH TETRATRICOPEPTIDE REPEATS 1; 1.
DR Pfam; PF13431; TPR_17; 1.
DR Pfam; PF13181; TPR_8; 1.
DR SMART; SM00028; TPR; 6.
DR SUPFAM; SSF48452; TPR-like; 3.
DR PROSITE; PS50005; TPR; 3.
DR PROSITE; PS50293; TPR_REGION; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000006813};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 406..439
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 491..524
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REPEAT 588..621
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
FT REGION 124..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 625 AA; 71916 MW; 0439FCC9A34C33C5 CRC64;
MEGCAAISQV AADWRQEKSH QKALGQQLDS ETQAAAFGRQ DHCGVRVPLG EKTQVVCEES
ARIPEKHNSW TVQRPDSKSL LVADEGRLLE AGNYILDSLP PVKTSLYLGQ DRCYREPPRQ
RWPRCGPGGR LARPDMSTAA GRERQAGSAQ RPAWGALKDH HRSENIDNHQ VKDCLFQLKC
HFTWKLVIDD TEIPDLEIRA SEHIENLDTN NIGMYNLQAY VSHLKGENDK ALQSLKEAED
LIQREHTDQL DRRSLVTWGN YAWVHYHMGR LADAKMYLDK VENTCKKFAS PFRYRMECPQ
MDCEEGWALL KCGGPNYKRA QACFEKALKV EAENPEFNAG YAIVTYRQDC DKSNVISLDP
LRKALKLNPE HGYIKVFLAL KLQDIGEEAE GEKYIKEALS NKSFQTYVFR YAAKFYRRKG
CTDKALQLFE KALQATPTSA YLHHQIGLCY KTQMFKVKGG TNRQDREIIG RFAQLAIDEF
QKTITDRPTF EMAYINLADL YAKIGQYEKA EENFQKALCM ENLPDHLQQE THFRYGRFQE
FHRKSDNKAI VHYLKGLKIE EKSFARDKLL NALEKLAKRR IQHNVCVVES FSLLGLVHKL
KGEVNEALLC YEKALRLTEH LNPMF
//
