ID G5B228_HETGA Unreviewed; 175 AA.
AC G5B228;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=Ferredoxin-2, mitochondrial {ECO:0000256|ARBA:ARBA00040942};
DE AltName: Full=Ferredoxin-1-like protein {ECO:0000256|ARBA:ARBA00041497};
GN ORFNames=GW7_08244 {ECO:0000313|EMBL:EHB03339.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB03339.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB03339.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
CC -!- COFACTOR:
CC Name=[2Fe-2S] cluster; Xref=ChEBI:CHEBI:190135;
CC Evidence={ECO:0000256|ARBA:ARBA00034078};
CC -!- SIMILARITY: Belongs to the adrenodoxin/putidaredoxin family.
CC {ECO:0000256|ARBA:ARBA00010914}.
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DR EMBL; JH168058; EHB03339.1; -; Genomic_DNA.
DR RefSeq; XP_004865544.1; XM_004865487.2.
DR AlphaFoldDB; G5B228; -.
DR STRING; 10181.G5B228; -.
DR Ensembl; ENSHGLT00100001246; ENSHGLP00100001210; ENSHGLG00100000960.
DR GeneID; 101714715; -.
DR KEGG; hgl:101714715; -.
DR CTD; 112812; -.
DR eggNOG; KOG3309; Eukaryota.
DR InParanoid; G5B228; -.
DR OMA; WQDPKSP; -.
DR OrthoDB; 36668at2759; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR Bgee; ENSHGLG00000018345; Expressed in adrenal gland and 10 other cell types or tissues.
DR GO; GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0140647; P:P450-containing electron transport chain; IEA:InterPro.
DR CDD; cd00207; fer2; 1.
DR Gene3D; 3.10.20.30; -; 1.
DR InterPro; IPR036010; 2Fe-2S_ferredoxin-like_sf.
DR InterPro; IPR001041; 2Fe-2S_ferredoxin-type.
DR InterPro; IPR001055; Adrenodoxin.
DR InterPro; IPR018298; Adrenodoxin_Fe-S_BS.
DR InterPro; IPR012675; Beta-grasp_dom_sf.
DR PANTHER; PTHR23426:SF34; FERREDOXIN-2, MITOCHONDRIAL; 1.
DR PANTHER; PTHR23426; FERREDOXIN/ADRENODOXIN; 1.
DR Pfam; PF00111; Fer2; 1.
DR PRINTS; PR00355; ADRENODOXIN.
DR SUPFAM; SSF54292; 2Fe-2S ferredoxin-like; 1.
DR PROSITE; PS51085; 2FE2S_FER_2; 1.
DR PROSITE; PS00814; ADX; 1.
PE 3: Inferred from homology;
KW Iron {ECO:0000256|ARBA:ARBA00023014};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00023014};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT DOMAIN 60..162
FT /note="2Fe-2S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51085"
SQ SEQUENCE 175 AA; 19194 MW; BEDCF5E6FDE42201 CRC64;
MAASTARGGV TVRLLLRAAR ASWWSRTGEA ALLTTRKFRT TGRRLAEGDI GGPERPGDVV
NVVFVDRSGQ RIPVSGRVGD NVLHLAQRHG VDLEGACEAS LACSTCHVYV SEAHLDLLPT
PEEREDDMLD MAPLLQENSR LGCQIVLTRE LEGVEFTLPK ITRNFYVDGH IPKPH
//
