ID G5B4T3_HETGA Unreviewed; 670 AA.
AC G5B4T3;
DT 14-DEC-2011, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2011, sequence version 1.
DT 24-JAN-2024, entry version 39.
DE RecName: Full=Leucine zipper tumor suppressor 3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=GW7_03200 {ECO:0000313|EMBL:EHB04294.1};
OS Heterocephalus glaber (Naked mole rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae;
OC Heterocephalus.
OX NCBI_TaxID=10181 {ECO:0000313|EMBL:EHB04294.1, ECO:0000313|Proteomes:UP000006813};
RN [1] {ECO:0000313|EMBL:EHB04294.1, ECO:0000313|Proteomes:UP000006813}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=21993625; DOI=10.1038/nature10533;
RA Kim E.B., Fang X., Fushan A.A., Huang Z., Lobanov A.V., Han L.,
RA Marino S.M., Sun X., Turanov A.A., Yang P., Yim S.H., Zhao X.,
RA Kasaikina M.V., Stoletzki N., Peng C., Polak P., Xiong Z., Kiezun A.,
RA Zhu Y., Chen Y., Kryukov G.V., Zhang Q., Peshkin L., Yang L., Bronson R.T.,
RA Buffenstein R., Wang B., Han C., Li Q., Chen L., Zhao W., Sunyaev S.R.,
RA Park T.J., Zhang G., Wang J., Gladyshev V.N.;
RT "Genome sequencing reveals insights into physiology and longevity of the
RT naked mole rat.";
RL Nature 479:223-227(2011).
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DR EMBL; JH168482; EHB04294.1; -; Genomic_DNA.
DR AlphaFoldDB; G5B4T3; -.
DR STRING; 10181.G5B4T3; -.
DR eggNOG; ENOG502QWFS; Eukaryota.
DR InParanoid; G5B4T3; -.
DR Proteomes; UP000006813; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR InterPro; IPR045329; LZTS.
DR PANTHER; PTHR19354; ZIPPER PUTATIVE TUMOR SUPPRESSOR 2 HOMOLOG-LIKE PROTEIN-RELATED; 1.
DR PANTHER; PTHR19354:SF6; ZIPPER PUTATIVE TUMOR SUPPRESSOR 3-RELATED; 1.
DR Pfam; PF06818; Fez1; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000006813}.
FT REGION 1..157
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 172..239
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 251..314
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 632..670
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 318..424
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 58..76
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 112..130
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..189
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 210..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 251..289
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 656..670
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 670 AA; 71813 MW; 499669A52F41B6DA CRC64;
MAKLETLPVR ADPGRDPLLA FAPRPSELGP PDPRLAMGSV GSGVAHAQEF AMKSVGTRTG
GGGSQGSFSG PRGSGSGTSR ERPGRYPSED KTLANSLYLN GELRGSDHTD VCGNVVGSSG
GSSSSGGSDK APPQYREPSH PPKLLATSGK LDQCSEPLVR PSAFKPVVPK NFHSMQNLCP
PQTNGTPEGR QGPGGLKGGL DKSRTMTPAG GSGGGLSDSG RNSLTSLPTY SSSYSQHLAP
LSASTSHINR IGTASYGSGS NGGGSGYQDL GTSDSGRASS KSGSSLSMGR PGHLGSGEGG
GGGLPFAACS PPSPSTLIQE LEERLWEKEQ EVAALRRSLE QSEAAVAQVL EERQKAWERE
LAELRQGCSG KLQQVARRAQ RAQQGLQLQV LRLQQDKKQL QEEAARLMRQ REELEDKVAA
CQKEQADFLP RMEETKWEVC QKAGEISLLK QQLKDSQADV SQKLSEIVGL RSQLREGRAS
LREKEEQLLS LRDSFGSKQA SLELAEGELP ATCHKPVLTP VDPADPQEAL ATCESDEAKM
RRQAGVAAAA SLVSMDGEVD AGGESGTRAL RREVGRLQAE LAAERRARER QGASFAEERR
VWLEEKEKVI EYQKQLQLSY VEMYQRNQQL ERRLRERGAA GGASTPTPQL GEEKKAWTPS
RLERIESTEI
//
